High Throughput Screening (HTS)
Sygnature Discovery
MARCH 14, 2025
Sygnature Discovery offers high throughput screening along with additional hit identification tools including virtual screening, knowledge-based design, and fragment screening.
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Target-directed cancer: protein-ligand interactions
Drug Target Review
NOVEMBER 1, 2023
For example, in the screening stage of a project we are trying to find initial starting points for optimisation by our medicinal and computational chemistry colleagues. In terms of compound libraries, we have a high-throughput screening library of about 200,000 ligands.
Why fragments?
Molecular Design
AUGUST 2, 2020
Paramin panorama Crystallographic fragment screens have been run recently against the main protease (at Diamond ) and the Nsp3 macrodomain (at UCSF and Diamond ) of SARS-Cov-2 and I thought that it might be of interest to take a closer look at why we screen fragments.
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