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Sara Amberntsson, Alison J Foster, Bhavik Chouhan, Stephen Wilkinson, Stephanie Harlfinger, Graham Smith, Jason G Kettle, Michael Niedbala, Stefan Kavanagh, Dominic P Williams Toxicology Research , 2025, 14, 3, tfaf054, [link] Interest in inhibiting target proteins through covalent binding mechanisms has increased in the last decade due to the potential for beneficial pharmacological properties.
The digital tide of Generative AI is sweeping across the globe, reshaping industries, revolutionizing creativity, and promising a future brimming with unimaginable possibilities. From crafting compelling prose to composing intricate melodies, from designing breathtaking visuals to simulating complex realities, Generative AI has moved from the realm of science fiction into our everyday lives with astonishing speed.
Weeks after shelving a TIGIT drug prospect, the biotech is seeking to sell off its assets and intellectual property in a bid to "maximize" shareholder value.
Imagine you are retrieving an API key/Bearer token from an external system to make a new callout to another external system. But there is one issue: you cannot determine when the new callout will take place, so you need to store the token value somewhere in your org for later use. Probably you will be thinking of storing it in your custom object or custom metadata.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
In a major leap forward for genetic and biomedical research, scientists have developed a powerful new artificial intelligence tool that can predict the 3D shape of chromosomes inside individual cells -- helping researchers gain a new view of how our genes work.
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Parental warmth and affection in early childhood can have life-long physical and mental health benefits for children, and new research points to an important underlying process: children's sense of social safety.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
As rising global temperatures alter ecosystems worldwide, animal species usually have two choices: adapt to changing local conditions or flee to a cooler clime. Ecologists have long assumed that the world's bird species were best equipped to respond to the pressures of climate change simply because they have the option of flying to higher altitudes or towards global poles.
Summer unofficially began over the weekend. To mark the occasion, here are a few hot items, freshly seared on the Drug Channels grill: Reactions from the Drug Channels community to the Most Favored Nation (MFN) pricing policy A reality check on whether plan sponsors truly want rebate reform What plan sponsors should know about the evolving profit models of pharmacy benefit managers (PBMs) Plus: A special moment for DCI on Capitol Hill.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Scientists show that wolves that are eating sea otters in Alaska have much higher concentrations of mercury than those eating other prey such as deer and moose.
"Generic Medications: The Unseen Struggle for Quality Control As the pharmaceutical industry grapples with the complexities of generic drug production, a hidden crisis is unfolding. Despite their lower price points, generic medications often fall short of their branded counterparts in terms of quality and consistency. But what if I told you there's a way to bridge this gap?
Researchers find high-fat diets set off metabolic dysfunction in cells, leading to weight gain, but these effects can be reversed by treatment with an antioxidant.
WEDNESDAY, May 28, 2025 Motorcycle helmet laws save lives and prevent many severe injuries, according to a new head-to-head study comparing two states.North Carolina mandates helmets for all motorcyclists, while South Carolina only requires r.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
A new method could soon unlock the vast repository of biological information held in the proteins of ancient soft tissues. The findings could open up a new era for palaeobiological discovery.
WEDNESDAY, May 28, 2025 -- Health officials at the World Health Organization are warning of a rise in cases from a new COVID-19 variant.The new variant, NB.1.8.1, has been spotted in the Mediterranean, Southeast Asia, and Western Pacific regions.
WEDNESDAY, May 28, 2025 Singer and actress Miley Cyrus says a rare voice disorder called Reinkes edema is behind her famous raspy voice and also makes singing live very hard.The 32-year-old pop star recently discussed the condition during an in.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
WEDNESDAY, May 28, 2025 The top U.S. health agency will no longer recommend the COVID-19 vaccine for healthy children and pregnant women.Tuesday's announcement by U.S. Health and Human Services Secretary Robert F. Kennedy Jr. bypasses the typical.
Results from a clinical trial show that giving people with high blood pressure an injection every six months can lead to a meaningful, sustained reduction in their blood pressure.
WEDNESDAY, May 28, 2025 A grid of electrodes slapped on a persons back might soon be able to help treat pain, spasms and paralysis, a new study says.The electrodes deliver enough low-voltage electrical stimulation through the skin to change the s.
Neurons deep in the brain not only help to initiate movement -- they also actively suppress it, and with astonishing precision. The findings are especially relevant for better understanding neurological disorders such as Parkinson's disease.
WEDNESDAY, May 28, 2025 Popular GLP-1 weight loss drugs like Ozempic and Zepbound can help reduce a womans risk for as many as 14 cancers associated with obesity, a new study says.People taking a GLP-1 drug had a 7% lower risk of developing an ob.
This study measured the growth rate of coral reefs in Honaunau Bay, Hawaii, using on-site data gathering and aerial imagery. Researchers found that the reefs are being eroded by sea urchin populations which have exploded due to overfishing in the area. The reefs are also threatened by climate change and water pollution, and their growth rates are not fast enough to counteract the erosion caused by the urchins.
WEDNESDAY, May 28, 2025 Preschoolers who dont naturally lose weight are more likely to develop full-fledged childhood obesity by age 9, a new study says.Most kids tend to see their body-mass index (BMI) decline between ages 1 and 6, before sta.
A series of experiments support spectral data recently collected by the James Webb Space Telescope that found evidence that the icy surface of Jupiter's moon Europa is constantly changing. Europa's surface ice is crystallizing at different rates in different places, which could point to a complex mix of external processes and geologic activity affecting the surface.
WEDNESDAY, May 28, 2025 -- Thanks to artificial intelligence (AI), more women might soon benefit from targeted breast cancer treatment, a new study says.AI can help identify women who might be helped by cancer therapies that target HER2, a protein.
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