Medical Chemistry and Therapies - Drug Discovery Digest

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Medical Chemistry

Therapies

How GPCR-targeting therapies are advancing the fight against inflammatory disease

Drug Target Review

JUNE 16, 2025

Targeting GPCRs to fight inflammatory diseases GPCR-targeting drugs are well known therapies for a range of disease types, including cardio-metabolic, central nervous system and endocrinological disorders. GPCR-targeting therapies such as DT-9046 represent a compelling opportunity in that respect, with major clinical and commercial potential.

Disease

Disease Therapies Small Molecule Immune Response

Addressing increasingly resistant drugs by infectious agents

Drug Target Review

SEPTEMBER 4, 2023

7,9 Dihydrofolate reductase-thymidylate synthase (DHFR) have been successfully exploited for the therapy of bacterial infections and other parasitic diseases such as malaria. 2011): State of the Art in African Trypanosome Drug Discovery, Current topic of medical chemistry. and Margaret, A. 11(10):1255-1274 Saavedra, E.,

Drugs

Drugs RNA DNA Disease

How GPCR-targeting therapies are advancing the fight against inflammatory disease

Addressing increasingly resistant drugs by infectious agents

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