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How nucleolar stress accelerates aging in mice

Drug Target Review

In 2005, he joined CNIO to lead the Genomic Instability Group where he has been ever since. Initial works from the lab concentrated on exploring the role of replicative stress in cancer and ageing, for which the group combined cell biology, mouse models and drug development projects.

RNA 65
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Precision Medicine in the Genomic Era

DrugBank

Conclusion Since the first GWAS was published in 2005, there have been more than 50,000 significant variant-trait associations identified. Evidence-Based Precision Medicine is Needed to Move Toward General Internal Precision Medicine. Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Disease 99
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Discovering an Antimalarial Drug in Mao’s China

Codon

Delays In the early 1980s, eager to push artemisinin onto the international market, China turned to the World Health Organization (WHO). It was only in 2005, after the emergence of widespread resistance of P. Eerily predictive in hindsight, the “hao” in these lines stood for the plant qinghao , or Artemisia annua L.

Drugs 141
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Neurobiology & Organismal Biology

Broad Institute

Notably, fragmented maternal care yields internalizing symptoms (cognitive rigidity) in female offspring, while producing externalizing consequences (attention deficits, social impairments) in male siblings. in molecular and cell biology and biochemistry from the University of Oxford.