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Accelerating Drug Discovery Through Repurposing

DrugBank

Key techniques include high-throughput screening (HTS), cell-based assays, and animal models. Cell-Based Assays In vitro, drug efficacy, and toxicity testing in cell cultures provide valuable preclinical data.

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Article FDA Thank You Draft guidance on potency assays for CGT products garners extensive stakeholder input

Agency IQ

Cell-based assays , while more complex to develop and use, offer another option for characterizing product activity at a slightly higher level, allowing sponsors to measure the further downstream effects of products (e.g., morphological cell changes or alterations in protein production or expression).