Broad Institute

JULY 26, 2022

Learn more PRISM Rapid, high-throughput multiplexed compound screening in genomically characterized human cancer cell-line models. Many additional tools, analysis pipelines, and applications developed by our scientists and collaborators are available on GitHub.

Compound Screening 52

Compound Screening FDA Approval Engineering RNA 52

Drug Target Review

NOVEMBER 1, 2023

We need to build the assays that we need for compound screening. With a structural technique such as X-ray crystallography we provide pictures of our inhibitors bound to their protein targets to help inform our computational and medicinal chemists in the design of improved inhibitors which is an iterative and very creative process.

Fragment Screening 96

Fragment Screening Biochemical Assays Small Molecule Biophysical Assays 96

KIF1A

AUGUST 28, 2024

I know I might sound like a broken record, but we have SO MUCH exciting news and information to share this month! ” While the primary focus of CIRM grants has been cell therapy, it has also promoted the use of cell-based disease modeling and compound screening, as well as the development of gene-based therapies.

Therapies 52

Therapies Compound Screening Research Treatment 52

The ChEMBL-og

APRIL 16, 2024

A significant effort has been made to correctly map the drug form of the EMA data by manually inspecting different EMA sources of information, such as the Product Information (Annex I: Summary of Product Characteristics and Annex III: Labelling and Package Leaflet) and/or Assessment Report, where available. University of Dundee: T.

Clinical Trials 108

Clinical Trials FDA Cell Based Assays Compound Screening 108