Drug Discovery World
MAY 2, 2024
Allogene Therapeutics has received a $15 million grant from the California Institute for Regenerative Medicine (CIRM) to support the development of ALLO-316, an AlloCAR T investigational product for the treatment of advanced or metastatic renal cell carcinoma (RCC). ALLO-316 targets CD70, which is highly expressed in RCC and is also selectively expressed in several cancers.
Science Daily: Pharmacology News
MAY 2, 2024
Researchers succeeded in conducting an almost perfect quantum teleportation despite the presence of noise that usually disrupts the transfer of quantum state.
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Drug Discovery World
MAY 2, 2024
A study led by the University of Oxford has successfully investigated human immunity against Covid-19 in people who already have antibodies, with the aim of advancing future vaccines and treatments. The results suggest that previous infection, together with vaccination, offers strong protection against the original Covid-19 strain. Over 99% of the UK population and 59% of the world’s population is seropositive, which means they already have antibodies against Covid-19.
Broad Institute
MAY 2, 2024
#WhyIScience Q&A: How a computational biologist balances work with life as an elite rower By Allessandra DiCorato May 2, 2024 Breadcrumb Home #WhyIScience Q&A: How a computational biologist balances work with life as an elite rower Liz Martin reflects on how her career in cancer biology complements her intense training on the water. By Allessandra DiCorato May 2, 2024 Credit: Lisa Worthy Liz Martin, an elite rower and a computational biologist at the Broad, in a lightweight women's quad at the 2
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
MAY 2, 2024
Hailed as a revolution in the treatment of many diseases, cell and gene therapy (CGT) is the fastest growing area of therapeutics. 2023 was a record year for CGTs, with seven new CGTs approved by the US Food and Drug Administration (FDA) across a variety of different disease areas. Perhaps most significantly, Casgevy (or exa-cel) from Vertex Pharmaceuticals and CRISPR Therapeutics, was approved to treat sickle cell disease and became the first gene therapy that uses CRISPR gene editing. 2024 is
Chemical Biology and Drug Design
MAY 2, 2024
Simultaneous inhibition of EGFR and VEGFR2 may improve the efficacy of cancer treatment. Understanding the macromolecular structures, activation mechanism, and pharmacophore features of both kinase inhibitors and their selectivity is essential in designing dual inhibitors of EGFR and VEGFR2. Abstract Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor 2 (VEGFR2) are known as valid targets for cancer therapy.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
MAY 2, 2024
A wild orangutan was observed applying a plant with known medicinal properties to a wound, a first for a wild animal.
BioPharma Drive: Drug Pricing
MAY 2, 2024
Delphia is developing medicines designed to overstress certain cellular pathways to the point tumor cells die, an approach the biotech calls “activation lethality.
Science Daily: Pharmacology News
MAY 2, 2024
Working with human breast and lung cells, scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many times, a hallmark of cancer cells.
Crown Bioscience
MAY 2, 2024
This post delves into some frequently asked questions about Omni Screen and its unique capabilities in providing compliant, large-scale cell line screening solutions that are not only cutting-edge but also aligned with industry standards and regulations. Whether you're a researcher, a biotech professional, or someone keen on understanding the nuances of cell line screening, this discussion will provide valuable insights into how Crown Bioscience can support your scientific endeavors.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
MAY 2, 2024
New catalyst is made from an inexpensive, abundant metal and table sugar. Catalyst converts carbon dioxide (CO2) into carbon monoxide, a building block for producing a variety of useful chemicals including syngas. With recent advances in carbon capture technologies, post-combustion carbon capture is becoming a plausible option to help tackle the global climate change crisis.
Quanticate
MAY 2, 2024
Innovative strategies paving the way for enhanced data quality, integrity and streamlined data validation and cleaning. The way we clean and validate data within clinical trials is continuously evolving, more than ever now with the advancements in technology that we are seeing across this industry year on year. These technological developments are reshaping the way data is handled, leading to improvements in the accuracy and efficiency of data.
Science Daily: Pharmacology News
MAY 2, 2024
New algorithm encourages robots to move more randomly to collect more diverse data for learning. In tests, robots started with no knowledge and then learned and correctly performed tasks within a single attempt. New model could improve safety and practicality of self-driving cars, delivery drones and more.
Drugs.com
MAY 2, 2024
THURSDAY, May 2, 2024 -- The active chemical in magic mushrooms could prove to be a powerful antidepressant, a new review finds.Psilocybin outperformed a variety of “control” treatments in easing symptoms of depression, researchers reported May.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Perficient: Drug Development
MAY 2, 2024
I recently became a mother for the third time, welcoming a beautiful baby girl in July 2023. Stepping into the whirlwind of newborn life with two other children in tow felt like diving headfirst into uncharted waters! Balancing the needs of three young humans has become my daily adventure, filled with equal parts chaos and love. Mo therhood , whether it’s the first or fifth time, is a beautiful yet wildly demanding journey that nearly always involves juggling multiple responsibilities simultane
Drugs.com
MAY 2, 2024
THURSDAY, May 2, 2024 -- An experimental cancer vaccine can quickly reprogram a person’s immune system to attack glioblastoma, the most aggressive and lethal form of brain cancer, a small, preliminary study has found.The cancer vaccine is based.
BioPharma Drive: Drug Pricing
MAY 2, 2024
The $1 billion dollar acquisition will add to Novartis’ pipeline of the targeted radiation drugs, giving it a potential lung cancer treatment.
Drugs.com
MAY 2, 2024
THURSDAY, May 2, 2024 -- Johnson & Johnson announced Wednesday that it would pay out more than $6.5 billion over the next 25 years to settle existing lawsuits claiming that its talc-containing products caused ovarian cancer. The settlement.
Drug Channels
MAY 2, 2024
Today’s guest post comes from Chris Dowd, Senior VP of Market Development at ConnectiveRx. Chris explains how the Inflation Reduction Act of 2022 (IRA) will impact hub, patient assistance programs (PAP), and affordability programs. He discusses steps manufacturers can take to accommodate the anticipated budget reductions while maintaining access and affordability for patients.
Drugs.com
MAY 2, 2024
THURSDAY, May 2, 2024 -- A looming presidential election, continued economic struggles and the threat of gun violence have a rising number of Americans more anxious this year compared to last, a new poll finds.The survey, conducted in early April.
BioPharma Drive: Drug Pricing
MAY 2, 2024
First quarter sales of the in-demand obesity drug were down slightly compared to the fourth quarter last year, as the company tries to meet demand.
Drugs.com
MAY 2, 2024
THURSDAY, May 2, 2024 — The U.S. Environmental Protection Agency (EPA) said it will spend $3 billion to help states and territories identify and replace lead water pipes."The science is clear, there is no safe level of lead exposure, and the.
Fierce BioTech
MAY 2, 2024
Robert Barrow, Chief Executive Officer of MindMed | Generalized anxiety disorder afflicts millions however, the latest treatment was approved in 2007. Now MindMed is advancing a new treatment paradigm.
Drugs.com
MAY 2, 2024
THURSDAY, May 2, 2024 -- Brianna Starr, 29, didn’t think twice about sunbathing without sunscreen, hoping to get a golden tan that to many connotes health and beauty.But when her sister was diagnosed with melanoma at the age of 19, she got.
addgene Blog
MAY 2, 2024
FITS In vitro CRISPR screens in immune cells have identified many putative regulators of immunity. However, in vitro screens cannot faithfully model the complex spatial, cellular, metabolic, and cytokine microenvironment that exists in vivo. Over the past five years, in vivo CRISPR screens have been used to interrogate T cells, an important immune cell type, in more complex and physiological microenvironments.
Drugs.com
MAY 2, 2024
THURSDAY, May 2, 2024 -- Artificial intelligence might be able to help doctors by filling out rote paperwork, but it’s not going to be useful in the ER anytime soon, a new study shows.OpenAI’s ChatGPT program provided inconsistent conclusions.
Crucial Data Solutions
MAY 2, 2024
In clinical research, innovations in technology are moving us down an exciting path, transforming traditional methodologies and paving the way. The post Wearables in Clinical Trials: Real Benefits Beyond the Hype appeared first on Crucial Data Solutions.
Drugs.com
MAY 2, 2024
THURSDAY, May 2, 2024 -- Add one more damaging consequence of sleep apnea to the list: New research suggests it's related to late-life epilepsy. Late-onset epilepsy is defined as seizures that tend to begin only after the age of 60. The condition.
Perficient: Drug Development
MAY 2, 2024
Are you looking to revolutionize your e-commerce strategy? Look no further than Salesforce Commerce Cloud (SFCC) and its powerful integrations with other Salesforce clouds. SFCC’s ability to seamlessly connect with Marketing Cloud, Service Cloud, and Sales Cloud opens up a world of possibilities for businesses seeking to enhance their customer engagement, drive sales, and optimize operations.
Drugs.com
MAY 2, 2024
THURSDAY, May 2, 2024 -- Giving your kid a drink, snack or small bag of fast food on the way home from day care might distract them during a busy commute, but it’s not doing their daily diet any favors, a new study warns.The hour after kids are.
H1 Blog
MAY 2, 2024
A Path to Inclusive Healthcare Clinical trials serve as the bedrock for advancements in medicine, guiding the development of new treatments and therapies. However, a critical issue plaguing these trials is the lack of diversity among participants, particularly from underrepresented racial and ethnic populations and medically underserved communities.
Drugs.com
MAY 2, 2024
THURSDAY, May 2, 2024 -- After investigation, the U.S. Department of Agriculture said Wednesday that the nation's ground beef supply is so far testing negative for the presence of H5N1 avian flu.In a statement, the agency said that its Food Safety.
BioPharma Drive: Drug Pricing
MAY 2, 2024
Metagenomi said the companies’ decision to part ways followed a “strategic prioritization” undertaken by Moderna, which has made several investments in gene editing research in recent years.
Drugs.com
MAY 2, 2024
THURSDAY, May 2, 2024 -- The number of American women who died at or soon after childbirth declined significantly in 2022, the latest government data shows, but the rate is still higher than pre-pandemic levels.The report from the U.S. National.
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