Mon.May 13, 2024

article thumbnail

New DDW Highlights episode: 8 May 2024

Drug Discovery World

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. A leading news story this week has been the announcement of positive Phase II results of a head and neck cancer trial, but there have been a number of other interesting clinical result announcements.

Trials 147
article thumbnail

Ajax, aiming for a better JAK drug, raises $95M to begin first tests

BioPharma Drive: Drug Pricing

Goldman Sachs and Eli Lilly are among those backing the startup, which claims its prospect could be more potent than the myelofibrosis therapies that have come to market in recent years.

Therapies 127
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

How structural biology is informing vaccine design

Drug Discovery World

Reece Armstrong speaks to Melanie Adams-Cioaba , Senior Director and General Manager of pharma (cryo-EM), Thermo Fisher Scientific about advances in vaccine design. RA: How can rational design approaches help advance vaccine development? MA: Regarding vaccine development specifically, and the role my team plays in the development of cryogenic electron microscopy (cryo-EM) technology, we see the study and dissemination of virus structures, and the proteins that comprise them, as vital to vacc

Vaccine 147
article thumbnail

Today's world: Fastest rate of carbon dioxide rise over the last 50,000 years

Science Daily: Pharmacology News

Today's rate of atmospheric carbon dioxide increase is 10 times faster than at any other point in the past 50,000 years, researchers have found through a detailed chemical analysis of ancient Antarctic ice.

Research 121
article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

$20 million donation supports neurodegeneration research

Drug Discovery World

The University of Texas MD Anderson Cancer Center has been awarded $20 million to strengthen neurodegeneration research. The donation was awarded to the Belfer Neurodegeneration Consortium (BNDC), which aims to develop five new medicines for Alzheimer’s disease and related disorders over the next 10 years, with the goal for two treatments to demonstrate clinical efficacy.

Research 130
article thumbnail

Plant virus treatment shows promise in fighting metastatic cancers in mice

Science Daily: Pharmacology News

An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, shows a new study. The treatment, composed of nanoparticles fashioned from the cowpea mosaic virus -- a virus that infects black-eyed pea plants -- showed remarkable success in improving survival rates and suppressing the growth of metastatic tumors across various cancer models, including colon, ovarian, melanoma and breast cancer.

Virus 118

More Trending

article thumbnail

What makes a memory? It may be related to how hard your brain had to work

Science Daily: Pharmacology News

The human brain filters through a flood of experiences to create specific memories. Why do some of the experiences in this deluge of sensory information become 'memorable,' while most are discarded by the brain? A computational model and behavioral study developed by Yale scientists suggests a new clue to this age-old question, they report in the journal Nature Human Behavior.

112
112
article thumbnail

Getting Abortion Pill Via Mail Order Is Quick, Safe & Effective

Drugs.com

MONDAY, May 13, 2024 -- Women who get abortion pills through the mail receive care that's as good as those who are required to get them in person from a clinic or doctor’s office, a new study says. Using a mail-order pharmacy to deliver the.

Pharmacy 111
article thumbnail

When Worlds Collide: The Theory of Real-World Evidence Meets Reality

FDA Law Blog: Biosimilars

By Jeffrey N. Gibbs & Ana Loloei & Véronique Li, Senior Medical Device Regulation Expert — FDA has long touted the use of real-world evidence ( RWE ). Extolling RWE, FDA has said “RWE can be leveraged to bring new products to market, evaluate the safety and effectiveness of existing products for new uses, and assess the continued performance and safety of products once on the market.

FDA 111
article thumbnail

Wegovy Can Help Heart Failure Patients Reduce Meds: Study

Drugs.com

MONDAY, May 13, 2024 -- People with heart failure are often prescribed what are known as loop diuretic medications to help reduce the fluid buildup that's a hallmark of the disease.Now, research suggests that taking the blockbuster weight loss drug.

Research 111
article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

First case of highly pathogenic avian influenza transmitted from cow to human confirmed

Science Daily: Pharmacology News

in March a farm worker who reported no contact with sick or dead birds, but who was in contact with dairy cattle, began showing symptoms in the eye and samples were collected by the regional health department to test for potential influenza A. Experts have now confirmed the first case of highly pathogenic avian influenza transmission from a mammal (dairy cow) to a human.

111
111
article thumbnail

Lesbian, Bisexual Women More Likely to Die Early Than Straight Peers

Drugs.com

MONDAY, May 13, 2024 (HealthDay news) -- Could being a lesbian or bisexual shorten your life? New research that analyzed decades of data on women suggests it might. What's driving the trend? Researchers point to discrimination as the primary.

article thumbnail

Takeda nabs option to license Alzheimer’s immunotherapies from AC Immune

BioPharma Drive: Drug Pricing

The deal — worth $100 million up front and potentially billions more later on — gives Takeda an exclusive option to license an Alzheimer’s vaccine and other “active immunotherapies.

article thumbnail

First Pig Kidney Recipient Dies Almost Two Months After Transplant

Drugs.com

MONDAY, May 13, 2024 -- Rick Slayman, the first person to receive a kidney transplant from a genetically modified pig, has died nearly two months after having the historic surgery.In a statement released Saturday, Slayman's family said they were.

98
article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

Nature's 3D printer: Bristle worms form bristles piece by piece

Science Daily: Pharmacology News

Molecular biologists provide exciting insights into the bristles of the marine annelid worm Platynereis dumerilii. Specialized cells, so-called chaetoblasts, control the formation of the bristles. Their mode of operation is astonishingly similar to that of a technical 3D printer.

73
article thumbnail

Sanofi gambles $80M on Fulcrum’s muscular dystrophy drug

BioPharma Drive: Drug Pricing

The deal gives the pharma partial rights to a medicine GSK once developed for heart disease but could soon become the first therapy for facioscapulohumeral muscular dystrophy.

article thumbnail

Police Seizures of Pills With Fentanyl Have Skyrocketed

Drugs.com

MONDAY, May 13, 2024 -- Police seizures of illicit fentanyl pills have soared in recent years, a new study has found.The number of pills containing fentanyl seized by law enforcement was 2,300 times greater in 2023 than in 2017 – more than 115.

59
article thumbnail

NewVale, an unorthodox venture firm, sets out to support biotech’s ‘infrastructure’

BioPharma Drive: Drug Pricing

The firm, which closed a $167 million fund, aims to fill a “crucial gap” by helping to grow the companies startups turn to for outsourced services, founder Todd Holmes told BioPharma Dive.

65
article thumbnail

New patent for Janssen Biotech drug BALVERSA

Drug Patent Watch

Annual Drug Patent Expirations for BALVERSA Balversa is a drug marketed by Janssen Biotech and is included in one NDA. It is available from one supplier.

Drugs 59
article thumbnail

Bridging the Genetic Diagnosis Gap: Strategies for Expanding Access to Rare Disease Therapies

Fierce BioTech

Bridging the Genetic Diagnosis Gap: Strategies for Expanding Access to Rare Disease Therapies pesurya Mon, 05/13/2024 - 13:44 Tue, 06/18/2024 - 13:00 Resource Type Webinar Heather McLaughlin, PhD, FACMG, NYCoQ, CGMB Michelle Hearn, CGC Colleen Caleshu, CGC Jeff Haroldson, PharmD Duration 60 Minutes As targeted treatments for rare diseases rapidly emerge, genetic diagnosis plays a crucial role in enabling access to clinical trials and precision therapies with the ultimate benefit of enhancing pat

article thumbnail

New patent for Kai Pharms drug PARSABIV

Drug Patent Watch

Annual Drug Patent Expirations for PARSABIV Parsabiv is a drug marketed by Kai Pharms Inc and is included in one NDA. It is available from one supplier.

Drugs 59
article thumbnail

Part 1: Understanding Selenium Python and Page Object Model Using PyDev in Eclipse

Perficient: Drug Development

Introduction to Selenium Web application testing is the primary use of Selenium, an open-source program that may be used for various tasks, such as web scraping and automating tedious tasks. Apart from supporting multiple programming languages, including Python, Java, C#, and others, it provides a suite of tools for automating web browsers across various platforms.

article thumbnail

New patent for Janssen Biotech drug ERLEADA

Drug Patent Watch

Annual Drug Patent Expirations for ERLEADA Erleada is a drug marketed by Janssen Biotech and is included in one NDA. It is available from one supplier.

Drugs 59
article thumbnail

Decoding Clinical Trial Costs and Efficiency Roadblocks

Vial

Introduction The biopharma industry is poised to make revolutionary advances in and redefine drug development, and the current climate for innovation appears ideal. However, progress from molecule to approved drug is hampered by extremely high costs and lengthy clinical trials , and approximately 90% of drugs that reach clinical trials fail. We explore the causes underlying the high costs associated with drug development and what value contract research organizations (CROs) bring to sponsors in

article thumbnail

New patent for Amarin Pharms drug VASCEPA

Drug Patent Watch

Annual Drug Patent Expirations for VASCEPA Vascepa is a drug marketed by Amarin Pharms and is included in one NDA. It is available from two suppliers.

Drugs 59
article thumbnail

We’re Accelerating Digital Transformation Like Never Before

Perficient: Drug Development

Last week, I had the privilege of attending our Accelerate Conference in St. Louis where I learned that Perficient’s secret sauce is really our people. We are a global digital consulting firm competing against the largest consulting firms in the world – and yet, we stand out. We heard from a couple of our largest clients who spoke about the groundbreaking work we are doing together.

article thumbnail

New patent for Novartis drug SCEMBLIX

Drug Patent Watch

Annual Drug Patent Expirations for SCEMBLIX Scemblix is a drug marketed by Novartis and is included in one NDA. It is available from one supplier.

Drugs 59
article thumbnail

Olivia Munn Underwent Hysterectomy After Breast Cancer Diagnosis

Drugs.com

MONDAY, May 13, 2024 -- Actress and "X-men" star Olivia Munn has revealed that she underwent egg retrieval and then a hysterectomy after being diagnosed with breast cancer. In an article published on Mother's Day, Munn told Vogue she opted for.

52
article thumbnail

The Financial Advantages of Outsourcing Vendor Audits

thought leadership

In today's dynamic business landscape, organizations in the drug, biologics, and medical device industries face the dual challenge of delivering quality products while managing tighter budgets and ensuring compliance with evolving regulatory standards. As companies strive to enhance product quality and meet stringent regulatory requirements to ensure the safety and efficacy of their products, vendor audits play a pivotal role.

article thumbnail

Yoga Can Help Heart Failure Patients Stay Strong

Drugs.com

MONDAY, May 13, 2024 -- Yoga can help improve the long-term health of people with heart failure, a new study has found.“Patients who practiced yoga on top of taking their medications felt better, were able to do more, and had stronger hearts than.

52
article thumbnail

New patent expiration for Azurity drug NYMALIZE

Drug Patent Watch

Annual Drug Patent Expirations for NYMALIZE Nymalize is a drug marketed by Azurity and is included in one NDA. It is available from one supplier.

Drugs 59
article thumbnail

Test Might Predict Which Kids Will Outgrow Peanut Allergy

Drugs.com

MONDAY, May 13, 2024 -- About a third of young children who are allergic to peanuts will outgrow the allergy by the age of 10, and an antibody test might predict who those kids might be.

52
article thumbnail

New patent for Beigene drug BRUKINSA

Drug Patent Watch

Annual Drug Patent Expirations for BRUKINSA Brukinsa is a drug marketed by Beigene and is included in one NDA. It is available from one supplier.

Drugs 59
article thumbnail

Could Having 'Skinny' Fat Cells Encourage Weight Gain?

Drugs.com

MONDAY, May 13, 2024 -- “Skinny” fat cells might actually make it harder to lose weight and easier to pack on extra pounds, a new study says.Researchers say it’s possible to predict if someone’s going to gain weight based solely on the size.

52