Thu.May 29, 2025

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Leprosy existed in America long before arrival of Europeans

Science Daily: Pharmacology News

Long considered a disease brought to the Americas by European colonizers, leprosy may actually have a much older history on the American continent. Scientists reveal that a recently identified second species of bacteria responsible for leprosy, Mycobacterium lepromatosis, has been infecting humans in the Americas for at least 1,000 years, several centuries before the Europeans arrived.

Disease 259
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Merck, Daiichi pull approval application for ADC in lung cancer

BioPharma Drive: Drug Pricing

A therapy at the center of their $22 billion alliance failed to extend survival in a type of lung tumor, leading the companies to abandon a U.S. submission.

Therapies 281
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Anthropologists spotlight human toll of glacier loss

Science Daily: Pharmacology News

Anthropologists have examined the societal consequences of global glacier loss.

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The medtech IPO window is finally open. Or is it?

BioPharma Drive: Drug Pricing

After a three-year drought, the industry is questioning whether the window for medtech public offerings is open following a small burst of activity.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Birds nested in Arctic alongside dinosaurs

Science Daily: Pharmacology News

Spring in the Arctic brings forth a plethora of peeps and downy hatchlings as millions of birds gather to raise their young. The same was true 73 million years ago, according to a new article. The paper documents the earliest-known example of birds nesting in the polar regions.

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Good Review Management Principles & Practices, Part One: Fundamental Values

thought leadership

On Tuesday, September 25 th , the FDA published a draft guidance containing recommendations on good review management principles and practices (GRMPs) for new drug applications (NDAs), Biologics license applications (BLAs), or efficacy supplements/supplements with clinical data. The document, entitled Good Review Management Principles and Practices for New Drug Applications and Biologics License Applications , applies to human drug applications and biosimilar biological product applications.

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FDA Prescription Drug User Fee Rates: Fiscal Year 2019

thought leadership

On Wednesday, August 1 st , FDA released a notice with updated prescription drug user fee rates for fiscal year 2019.

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Does planting trees really help cool the planet?

Science Daily: Pharmacology News

Replanting forests can help cool the planet even more than some scientists once believed, especially in the tropics. But even if every tree lost since the mid-19th century is replanted, the total effect won't cancel out human-generated warming.

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Novel Cell Lysis Solution: Simplifying Scalable Viral Vector Harvest

Fierce BioTech

Novel Cell Lysis Solution: Simplifying Scalable Viral Vector Harvest Download our free whitepaper to discover how you can boost lysis efficiency, maximize viral yield, and streamline your downstream process. smarcus Thu, 05/29/2025 - 10:25 Download our free whitepaper to discover how you can boost lysis efficiency, maximize viral yield, and streamline your downstream process.

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Electronic tattoo gauges mental strain

Science Daily: Pharmacology News

Researchers gave participants face tattoos that can track when their brain is working too hard. The study introduces a non-permanent wireless forehead e-tattoo that decodes brainwaves to measure mental strain without bulky headgear. This technology may help track the mental workload of workers like air traffic controllers and truck drivers, whose lapses in focus can have serious consequences.

Research 262
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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A Novel Approach for Improved Bioavailability in Solid Dosage Forms

Alta Sciences

A Novel Approach for Improved Bioavailability in Solid Dosage Forms tchichekian Fri, 05/30/2025 - 02:59 Publication Spray-Drying-Nanosuspensions-ebook.

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Rock record illuminates oxygen history

Science Daily: Pharmacology News

A new study reveals that the aerobic nitrogen cycle in the ocean may have occurred about 100 million years before oxygen began to significantly accumulate in the atmosphere, based on nitrogen isotope analysis from ancient South African rock cores. These findings not only refine the timeline of Earth's oxygenation but also highlight a critical evolutionary shift, where life began adapting to oxygen-rich conditions -- paving the way for the emergence of complex, multicellular organisms like humans

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Intellia filing spurs safety concerns over CRISPR drug

BioPharma Drive: Drug Pricing

Shares lost a quarter of their value after the company disclosed, in a regulatory filing, a life-threatening adverse event in a study testing one of its gene editing treatments in a deadly heart condition.

Treatment 238
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Long shot science leads to revised age for land-animal ancestor

Science Daily: Pharmacology News

The fossils of ancient salamander-like creatures in Scotland are among the most well-preserved examples of early stem tetrapods -- some of the first animals to make the transition from water to land. Thanks to new research, scientists believe that these creatures are 14 million years older than previously thought. The new age -- dating back to 346 million years ago -- adds to the significance of the find because it places the specimens in a mysterious hole in the fossil record called Romer's Gap

Science 203
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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HHS terminates Moderna contract to develop bird flu vaccine

BioPharma Drive: Drug Pricing

The funding was meant to help the U.S. prepare for pandemics triggered by avian flu strains, but now leaves the future of Moderna’s program uncertain.

Vaccine 317
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A cheap and easy potential solution for lowering carbon emissions in maritime shipping

Science Daily: Pharmacology News

Reducing travel speeds and using an intelligent queuing system at busy ports can reduce greenhouse gas (GHG) emissions from oceangoing container vessels by 16-24%, according to researchers. Not only would those relatively simple interventions reduce emissions from a major, direct source of greenhouse gases, the technology to implement these measures already exists.

Research 147
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RFK Jr. May Block Government Scientists From Publishing in Top Medical Journals

Drugs.com

THURSDAY, May 29, 2025 — U.S. Health and Human Services Secretary Robert F. Kennedy Jr. said this week that he may no longer allow government scientists to publish research in top medical journals. Kennedy made the statement on a podcast.

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Sustained in the brain: How lasting emotions arise from brief stimuli, in humans and mice

Science Daily: Pharmacology News

Humans and mice share persistent brain-activity patterns in response to adverse sensory experience, scientists find, opening a window to our emotions and, perhaps, neuropsychiatric disorders.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Belly Fat Linked To Psoriasis

Drugs.com

THURSDAY, May 29, 2025 Belly flab appears to be a stronger warning sign for psoriasis than fat located elsewhere on the body, a new study says.Fat around the abdomen is more strongly linked to psoriasis risk that total body fat, particularly in w.

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Genetic basis of purring in cats

Science Daily: Pharmacology News

Whether you are lucky enough to have a cat companion or must merely live this experience vicariously through cat videos, Felis catus is a familiar and comforting presence in our daily lives. Unlike most other feline species, cats exhibit sociality, can live in groups, and communicate both with other cats and humans, which is why they have been humans' trusted accomplices for millennia.

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Marijuana Use Linked to Early Signs of Heart Damage

Drugs.com

THURSDAY, May 29, 2025 — Smoking or eating marijuana on a regular basis may damage a healthy person's blood vessels much like tobacco does, a small study finds. Researchers from the University of California, San Francisco (UCSF) looked at the.

Research 193
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How does coffee affect a sleeping brain?

Science Daily: Pharmacology News

Coffee can help you stay awake. But what does caffeine actually do to your brain once you're asleep? Using AI, a team of researchers has an answer: it affects the brain's 'criticality'.

Research 186
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Pizza, Soup and Chicken Among Top Sources of Sodium for All Americans

Drugs.com

THURSDAY, May 29, 2025 These days Americans can agree on few things, but unfortunately, pizza, soup and chicken arent among them, a new study says.Those three foods are some of the main sources of sodium for Americans of all racial and ethnic gro.

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The future of AI regulation: Why leashes are better than guardrails

Science Daily: Pharmacology News

Many policy discussions on AI safety regulation have focused on the need to establish regulatory 'guardrails' to protect the public from the risks of AI technology. Experts now argue that, instead of imposing guardrails, policymakers should demand 'leashes.

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Dementia Tied To Heart, Metabolic Diseases

Drugs.com

THURSDAY, May 29, 2025 Heart disease, strokes and diabetes contribute to many dementia cases in the United States, but the risk is not equal everywhere, a new study says.Overall, more than a third (37%) of U.S. dementia cases are linked to eight c.

Disease 158
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Evolution of a single gene allowed the plague to adapt, survive and kill much of humanity over many centuries

Science Daily: Pharmacology News

Scientists have documented the way a single gene in the bacterium that causes bubonic plague, Yersinia pestis, allowed it to survive hundreds of years by adjusting its virulence and the length of time it took to kill its victims, but these forms of plague ultimately died out.

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Singing Soothes The Savage Infant, Clinical Trial Says

Drugs.com

THURSDAY, May 29, 2025 Singing to your baby can soothe them considerably and improve their overall mood, a new clinical trial shows.Parents given smartphone-based music enrichment training sang more often to their babies, and those babies were g.

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Could 'pausing' cell death be the final frontier in medicine on Earth and beyond?

Science Daily: Pharmacology News

The process of necrosis, a form of cell death, may represent one of the most promising ways to change the course of human aging, disease and even space travel, according to a new study.

Disease 232
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New technique expands cells to sequence DNA and capture fine structural details

Broad Institute

New technique expands cells to sequence DNA and capture fine structural details By Allessandra DiCorato May 29, 2025 Breadcrumb Home New technique expands cells to sequence DNA and capture fine structural details Using this method, scientists discovered key protein and gene activity changes in aging and in a rare disease called progeria. By Allessandra DiCorato May 29, 2025 Credit: Buenrostro lab Example of expansion in situ genome sequencing, showing a physically expanded cell nucleus from an i

DNA 133
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New quantum visualization technique to identify materials for next generation quantum computing

Science Daily: Pharmacology News

Scientists have developed a powerful new tool for finding the next generation of materials needed for large-scale, fault-tolerant quantum computing. The significant breakthrough means that, for the first time, researchers have found a way to determine once and for all whether a material can effectively be used in certain quantum computing microchips.

Research 216
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Burning Out? An E-Tattoo Can Track Mental Strain

Drugs.com

THURSDAY, May 29, 2025 — Ever thought so long and hard on a problem that your forehead grew hot, your brain became frazzled and your eyes grew bleary? A new temporary tattoo can help measure that sort of mental strain, researchers.

Research 132
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Listening to electrons talk

Science Daily: Pharmacology News

Researchers present new experimental and theoretical results for the bound electron g-factor in lithium-like tin which has a much higher nuclear charge than any previous measurement. The experimental accuracy reached a level of 0.5 parts per billion. Using an enhanced interelectronic QED method, the theoretical prediction for the g-factor reached a precision of 6 parts per billion.

Research 150