Mon.May 26, 2025

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Megalodon: The broad diet of the megatooth shark

Science Daily: Pharmacology News

Contrary to widespread assumptions, the largest shark that ever lived -- Otodus megalodon -- fed on marine creatures at various levels of the food pyramid and not just the top. Scientists analyzed the zinc content of a large sample of fossilized megalodon teeth, which had been unearthed above all in Sigmaringen and Passau, and compared them with fossil teeth found elsewhere and the teeth of animals that inhabit our planet today.

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How AI and LLMs are transforming drug discovery: part 2

Drug Target Review

The integration of artificial intelligence (AI) into scientific workflows represents both tremendous opportunity and significant challenges. I recently discussed the subject with two founders at the cutting edge of this transformation: Andr Frana of Ergodic and Eli Pollock of Ontologic. We considered the barriers scientists face when adopting AI tools , contrasting approaches to building AI systems for specialised domains, and their visions for how these technologies will reshape scientific work

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Ervogastat

New Drug Approvals

Ervogastat CAS 2186700-33-2 Non-alcoholic Steatohepatitis (NASH) with Liver Fibrosis (FAST TRACK – U.S.) 2-[5-[(3-Ethoxy-2-pyridinyl)oxy]-3-pyridinyl]- N -[(3 S )-tetrahydro-3-furanyl]-5-pyrimidinecarboxamide ( S )-2-(5-((3-Ethoxypyridin-2-yl]oxy]pyridin-3-yl)- N -(tetrahydrofuran-3-yl)pyrimidine-5-carboxamide PF 06865571 BSOIY5AKQW 407.4 g/mol, C 21 H 21 N 5 O 4 2-[5-(3-ethoxypyridin-2-yl)oxypyridin-3-yl]- N -[(3 S )-oxolan-3-yl]pyrimidine-5-carboxamide Originator Pfizer Class Amides; Eth

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Unveiling the Hidden Drivers of Switzerland’s Pharma Industry

Drug Patent Watch

"The Secret Sauce Behind Switzerland's Thriving Pharma Scene: It's Not Just About Chocolate and Mountains As the global pharma landscape continues to evolve, one country stands out for its remarkable success: Switzerland. With a market share of over 25% of the global pharmaceutical industry, the Swiss pharma sector is a powerhouse to be reckoned with.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Tackling complex manufacturing challenges in modern drug development

Drug Target Review

Daniel Galbraith, Chief Scientific Officer at Solvias , brings extensive expertise in the pharmaceutical and biotechnology sectors. In his role, he provides both strategic and technical guidance to Solvias, a global Contract Research Organisation (CRO) that offers critical analytical services to the pharmaceutical industry. With a particular focus on biologics, cell, and gene therapies, Galbraiths work is centred on equipping drug developers with the tools, insights, and support needed to advanc

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Flotufolastat F 18

New Drug Approvals

Flotufolastat F 18 Flotufolastat F-18 Gallium POSLUMA CAS 2305081-64-3 18FrhPSMA-7.3 18F-rhPSMA-7.3 1537.3 g/mol C 63 H 96 FGaN 12 O 25 Si gallium;2-[7-[(1 S )-1-carboxy-4-[[(2 R )-1-[[(1 R )-1-carboxy-5-[[4-[[(4 R )-4-carboxy-4-[[(4 S )-4-carboxy-4-[[(1 S )-1,3-dicarboxypropyl]carbamoylamino]butanoyl]amino]butyl]amino]-4-oxobutanoyl]amino]pentyl]amino]-3-[[4-[di tert -butyl(fluoranyl)silyl]benzoyl]amino]-1-oxopropan-2-yl]amino]-4-oxobutyl]-4,10-bis(carboxylatomethyl)-1,4,7,10-tetrazacyclododec-