Science Daily: Pharmacology News
MAY 29, 2025
Long considered a disease brought to the Americas by European colonizers, leprosy may actually have a much older history on the American continent. Scientists reveal that a recently identified second species of bacteria responsible for leprosy, Mycobacterium lepromatosis, has been infecting humans in the Americas for at least 1,000 years, several centuries before the Europeans arrived.
Drugs.com
JUNE 2, 2025
MONDAY, June 2, 2025 Removing fluoride from the U.S. water supply could result in more than 25 million more decayed teeth in children and teenagers within five years, a new study warns.Thats the equivalent of a decayed tooth for 1 of every 3 kid.
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BioPharma Drive: Drug Pricing
JUNE 2, 2025
The oncology giant will pay $1.5 billion to co-develop a BioNTech drug that targets the proteins PD1 and VEGF, following Merck, and Pfizer into what’s become a competitive development race.
Covalent Modifiers
MAY 27, 2025
Birgit Wilding, Lydia Woelflingseder, Anke Baum, Krzysztof Chylinski, Gintautas Vainorius, Neil Gibson, Irene C. Waizenegger, Daniel Gerlach, Martin Augsten, Fiona Spreitzer, Yukina Shirai, Masachika Ikegami, Sylvia Tilandyov, Dirk Scharn, Mark A. Pearson, Johannes Popow, Anna C. Obenauf, Noboru Yamamoto, Shunsuke Kondo, Frans L. Opdam, Annemarie Bruining, Shinji Kohsaka, Norbert Kraut, John V.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Drug Patent Watch
MAY 27, 2025
"Unlock Hidden Profits in Pharmaceutical R&D: A recent analysis of top-selling medications reveals that companies that closely monitor their competitors' patent portfolios are 3x more likely to achieve a higher return on investment in drug development. By staying one step ahead of the competition, can you revolutionize your approach to pharmaceutical innovation?
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
MAY 27, 2025
TUESDAY, May 27, 2025 -- The U.S. Food and Drug Administration has approved Zoryve (roflumilast) topical foam 0.3 percent for the treatment of plaque psoriasis of the scalp and body in adult and pediatric patients 12 years of age and older.Through.
BioPharma Drive: Drug Pricing
MAY 31, 2025
AstraZeneca and Daiichi Sankyo’s drug extended survival by 30% compared to a widely used regimen, further establishing its importance as a second-line treatment option.
Covalent Modifiers
MAY 28, 2025
Sara Amberntsson, Alison J Foster, Bhavik Chouhan, Stephen Wilkinson, Stephanie Harlfinger, Graham Smith, Jason G Kettle, Michael Niedbala, Stefan Kavanagh, Dominic P Williams Toxicology Research , 2025, 14, 3, tfaf054, [link] Interest in inhibiting target proteins through covalent binding mechanisms has increased in the last decade due to the potential for beneficial pharmacological properties.
Fierce BioTech
JUNE 2, 2025
In conversation with Fierce Biotechs Chris Hayden, Austin Read, head of PPD CorEvitas Precision Medicine, Thermo Fisher Scientific, unpacks the evolving landscape of precision therapeutic and di | Austin Read of Thermo Fisher Scientific discusses how combining biospecimens with real-world data is advancing diagnostics, treatment and the future of patient care.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Science Daily: Pharmacology News
MAY 29, 2025
Anthropologists have examined the societal consequences of global glacier loss.
Drugs.com
JUNE 2, 2025
MONDAY, June 2, 2025 A dads eating habits can have a profound effect on their kids diets, even when those children are nothing but a twinkle in his eye, a new study says.Men who established a healthy diet as teens were more likely to model healt.
BioPharma Drive: Drug Pricing
JUNE 2, 2025
Phase 3 results revealed Monday led shares to surge and should yield an approval application in IgA nephropathy, a competitive corner of drug research, later this year.
Covalent Modifiers
JUNE 2, 2025
Kyle Ghaby, Benot Roux bioRxiv 2025.05.28.656658; doi: [link] There is increasing interest in the discovery of small-molecule inhibitors that form covalent bonds with their targets for therapeutic applications. Nevertheless, identifying clear rational design principles remains challenging because the action of these molecules cannot be understood as common noncovalent inhibitors.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Perficient: Drug Development
MAY 27, 2025
In the ever-evolving world of content management systems (CMS), there are many options to choose fromWordPress, Joomla, Drupal, and others. But for developers who love clean code, flexibility, and control, October CMS stands out as a modern, elegant solution built on the popular Laravel PHP framework. What is October CMS? October CMS is an open-source, free CMS that makes web building easier without compromising power or flexibility.
Science Daily: Pharmacology News
MAY 29, 2025
A new study finds that if global warming exceeds the Paris Climate Agreement targets, the non-polar glacier mass will diminish significantly. However, if warming is limited to 1.5 degrees Celsius, at least 54 per cent could be preserved -- more than twice as much ice as in a 2.7 C scenario.
Drugs.com
MAY 31, 2025
SATURDAY, May 31, 2025 Stress from work doesnt always stay at the office and it may be affecting more than just your mood. A new study finds that your dog may be picking up on it, too, especially if you have a hard time letting go of work worri.
BioPharma Drive: Drug Pricing
MAY 27, 2025
The agency recommends manufacturers update their vaccines to target the JN.1 strain. At the same time, HHS head Robert F. Kennedy Jr. is removing guidance that healthy children and pregnant women receive COVID shots.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drug Target Review
JUNE 2, 2025
Bioconjugates are rapidly emerging as a key frontier in targeted therapies, particularly through Antibody-Drug Conjugates (ADCs) , which combine antibodies with cytotoxic drugs to deliver more precise and effective treatments. This fusion enables precise delivery of potent drugs directly to cancer cells or other targeted tissues, significantly improving the therapeutic impact while minimising harm to healthy cells.
Perficient: Drug Development
JUNE 2, 2025
In this era of Web development, Next.JS and Vercel is the powerful couple. Next.JS offers performance, scalability and flexibility in building web applications whereas Vercel provides the easy and smooth deployment experience tailored for it. Today, in this blog, we will cover the step-by-step process of deploying a Next.JS app on Vercel. We will also cover some best practices and key configurations to ensure the optimal performance in production.
Science Daily: Pharmacology News
MAY 29, 2025
Replanting forests can help cool the planet even more than some scientists once believed, especially in the tropics. But even if every tree lost since the mid-19th century is replanted, the total effect won't cancel out human-generated warming.
Drug Patent Watch
JUNE 2, 2025
"The Patent Paradox: How Big Pharma's Web of Exclusivity is Suffocating Innovation As the world grapples with the rising costs of healthcare, a hidden culprit is quietly strangling the development of life-saving treatments: the 'patent thicket.' In a system designed to incentivize innovation, these complex webs of exclusive rights are instead fueling a culture of exploitation, where pharmaceutical giants use their patents to stifle competition and reap exorbitant profits.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
BioPharma Drive: Drug Pricing
MAY 27, 2025
City will receive $46 million from Biogen under the alliance. Elsewhere, Angelini Pharma licensed a rare disease therapy and the FDA refused to review a Savara lung drug.
thought leadership
MAY 29, 2025
On Tuesday, September 25 th , the FDA published a draft guidance containing recommendations on good review management principles and practices (GRMPs) for new drug applications (NDAs), Biologics license applications (BLAs), or efficacy supplements/supplements with clinical data. The document, entitled Good Review Management Principles and Practices for New Drug Applications and Biologics License Applications , applies to human drug applications and biosimilar biological product applications.
Perficient: Drug Development
JUNE 2, 2025
Mobile App development is rapidly growing and so is the expectation of robust support. “Mobile first” is the set paradigm for many application development teams. Unlike web deployment, an app release has to go through the review process via App Store Connect and Google Play. Minor or major releases follow the app review same process, which can take 1-4 days.
Science Daily: Pharmacology News
MAY 29, 2025
A new study reveals that the aerobic nitrogen cycle in the ocean may have occurred about 100 million years before oxygen began to significantly accumulate in the atmosphere, based on nitrogen isotope analysis from ancient South African rock cores. These findings not only refine the timeline of Earth's oxygenation but also highlight a critical evolutionary shift, where life began adapting to oxygen-rich conditions -- paving the way for the emergence of complex, multicellular organisms like humans
Chemical Biology and Drug Design
JUNE 2, 2025
This study investigates the neuroprotective effects of Kisspeptin-54 in ischemic stroke. In mice with induced stroke, Kisspeptin-54 reduced brain damage, improved neurological function, and restored occludin levels, strengthening the bloodbrain barrier. The findings reveal that Kisspeptin-54 enhances endothelial resilience through GATA-4-driven occludin expression, suggesting a promising therapeutic approach for stroke treatment.
BioPharma Drive: Drug Pricing
JUNE 2, 2025
The pharma giant is betting that Blueprint, whose research revolves around a certain kind of tyrosine kinase, will be a boost to its immunology business.
thought leadership
MAY 29, 2025
On Wednesday, August 1 st , FDA released a notice with updated prescription drug user fee rates for fiscal year 2019.
Perficient: Drug Development
MAY 27, 2025
In todays world, the Internet of Things (IoT) is revolutionizing industries across the globe by connecting devices, systems, and people in ways that were once unimaginable. From smart homes to advanced manufacturing, IoT is creating new opportunities for innovation, efficiency, and data-driven decision-making. At the forefront of this transformation is Microsoft Azure, a cloud computing platform that has become a powerhouse for IoT operations.
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