Science Daily: Pharmacology News
MAY 14, 2025
The northern white rhinoceros is one of the rarest animals on Earth, with just two females left and no natural way for the species to reproduce. Now, scientists have mapped the entire genome of a northern white rhino. This represents a crucial step toward bringing the critically endangered species back from the edge using advanced reproductive technologies.
Drugs.com
MAY 14, 2025
WEDNESDAY, May 14, 2025 -- Migraines don’t just cause headaches. These attacks often are accompanied by symptoms like light and sound sensitivity, nausea, neck pain and dizziness. What’s more, those non-headache symptoms tend to crop.
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BioPharma Drive: Drug Pricing
MAY 14, 2025
The new acquisition from Boston Pharmaceuticals adds to a wave of dealmaking undertaken by GSK to build its liver disease franchise.
Covalent Modifiers
MAY 18, 2025
Nafizul Haque Kazi, Nikolas Klink, Kai Gallant, Gian-Marvin Kipka & Malte Gersch Nat Struct Mol Biol , 2025 [link] The mitochondrial deubiquitinase ubiquitin-specific protease (USP) 30 negatively regulates PINK1parkin-driven mitophagy. Whether enhanced mitochondrial quality control through inhibition of USP30 can protect dopaminergic neurons is currently being explored in a clinical trial for Parkinsons disease.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
LifeSciVC
MAY 14, 2025
By Cody Tranbarger, EIR at Atlas Venture, as part of the From The Trenches feature of LifeSciVC Its an interesting time to be thinking about space. Just a few months ago, SpaceX captivated and inspired the world by catching a reusable rocket booster with mechanical chopsticks for the first time. Meanwhile, humanitys march toward a multi-planetary future continues, with Mars on the itinerary for the 2030s (unless youre on Elon time ).
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
MAY 14, 2025
WEDNESDAY, May 14, 2025 Exercise and sports appear to help kids avoid mental health problems as they grow into young adults, a new study says.Young children who participated in sports teams and physical education classes were less likely to d.
BioPharma Drive: Drug Pricing
MAY 14, 2025
The research collaboration, under which Septerna will receive more than $200 million in upfront and near-term fees, is the latest deal Novo has struck to expand its obesity pipeline.
Chemical Biology and Drug Design
MAY 12, 2025
CRISPR-CAS9 is an innovative gene editing technology to precisely remove or incorporate into the gene of interest; CRISPR-CAS9 shows promising results in HIV treatment. ABSTRACT Clustered regularly interspaced short palindromic repeats (CRISPR/Cas system) is now the predominant approach for genome editing. Compared to conventional genetic editing methods, CRISPR/Cas technology offers several advantages that were previously unavailable.
Drug Patent Watch
MAY 14, 2025
"Reviving Old Medicines: How AI-Powered Repurposing is Revolutionizing the Pharmaceutical Industry The pharmaceutical industry is on the cusp of a revolution, driven by the power of computational drug repurposing. By leveraging cutting-edge AI and machine learning algorithms, researchers are breathing new life into old medicines, unlocking unprecedented potential for treating a wide range of diseases.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Science Daily: Pharmacology News
MAY 15, 2025
A research team has developed and safely delivered a personalized gene editing therapy to treat an infant with a life-threatening, incurable genetic disease. The infant, who was diagnosed with the rare condition carbamoyl phosphate synthetase 1 (CPS1) deficiency shortly after birth, has responded positively to the treatment. The process, from diagnosis to treatment, took only six months and marks the first time the technology has been successfully deployed to treat a human patient.
Drugs.com
MAY 14, 2025
WEDNESDAY, May 14, 2025 More U.S. teenagers are getting weight-loss surgery, despite the discovery of new drugs like Ozempic/Wegovy that help people drop pounds surgery-free, a new study says.Weight loss surgeries for teens increased 15% between 2.
BioPharma Drive: Drug Pricing
MAY 14, 2025
Shareholders in Bluebird now have a choice of two offers from would-be acquirers Carlyle and SK Capital. Elsewhere, Cytokinetics shared more aficamten data and BridgeBio started a new kind of Attruby trial.
Drug Target Review
MAY 14, 2025
The integration of artificial intelligence (AI) into scientific workflows represents both tremendous opportunity and significant challenges. I recently discussed the subject with two founders at the cutting-edge of this transformation: Andr Frana of Ergodic and Eli Pollock of Ontologic. We explored the barriers scientists face when adopting AI tools , contrasting approaches to building AI systems for specialised domains, and their visions for how these technologies will reshape scientific work.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
New Drug Approvals
MAY 17, 2025
all-P-ambo -2′- O -(2-Methoxyethyl)-5-methyl- P -thiocytidylyl-(3’5′)-2′- O -(2-methoxyethyl)adenylyl-(3’5′)-2′- O -(2-methoxyethyl)- P -thioguanylyl-(3’5′)-2′- O -(2-methoxyethyl)guanylyl-(3’5′)-2′- O -(2-methoxyethyl)- P -thioadenylyl-(3’5′)- P -thiothymidylyl-(3’5′)-2′-deoxy- P -thioadenylyl-(3’5′)-2′-deoxy-5-methyl- P -thiocytidylyl-(3’5′)-2′-deoxy-
Science Daily: Pharmacology News
MAY 15, 2025
Until now, most research has used either generalized cell samples or organoids made from just one type of tropical fruit bat, and only from a single organ. But a breakthrough has arrived: a research team has now created the world's most comprehensive bat organoid platform. These 'mini-organs' are grown from five common bat species found across Asia and Europe and represent four different organs -- airway, lungs, kidneys, and small intestine.
Drugs.com
MAY 14, 2025
WEDNESDAY, May 14, 2025 U.S. Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. is under fire after posting photos of himself and his grandchildren swimming in a long-polluted creek. The water at Rock Creek Park in Washington, D.C., i.
Perficient: Drug Development
MAY 14, 2025
HCL Commerce v9.1 release saw a major change in features, functionality, and technology. This blog series will focus on each of these components separately. Some examples of these changes include HCL Commerce Search, which is powered by Elasticsearch, a modern storefront that uses Next.js, containerized cloud native architecture, modern business user tooling, and provides support for new integrations and companion software.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Crown Bioscience
MAY 14, 2025
Spatial biology is transforming our understanding of tissue microenvironments, providing unprecedented insights into gene expression and protein interactions in situ. By preserving spatial context, researchers can gain a deeper comprehension of cellular heterogeneity and the intricate communication between cells within tissues. This field is particularly valuable in studying complex biological systems, such as tumors, the immune system, and neurological networks, where spatial relationships sign
New Drug Approvals
MAY 15, 2025
Leniolisib CAS 1354690-24-6 WeightAverage: 450.466 Monoisotopic: 450.199108558 Chemical FormulaC 21 H 25 F 3 N 6 O 2 CDZ-173-NX CDZ173 CDZ173-NX 1-[(3S)-3-({6-[6-methoxy-5-(trifluoromethyl)pyridin-3-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-yl}amino)pyrrolidin-1-yl]propan-1-one FDA APPROVED Joenja , 3/24/2023, To treat activated phosphoinositide 3-kinase delta syndrome Drug Trials Snapshot Leniolisib (INN [3] [4] ), sold under the brand name Joenja , is a medication used for the treatment of acti
Science Daily: Pharmacology News
MAY 14, 2025
Evidence of a unique T cell may explain why urban children are more prone to allergies than rural children. Differences in the development of the gut microbiome may be an underlying cause.
Drugs.com
MAY 14, 2025
WEDNESDAY, May 14, 2025 -- Migraines dont just cause headaches.These attacks often are accompanied by symptoms like light and sound sensitivity, nausea, neck pain and dizziness.Whats more, those non-headache symptoms tend to crop up before a ful.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Perficient: Drug Development
MAY 15, 2025
Today, we celebrate Global Accessibility Awareness Day (GAAD) , an annual event dedicated to raising awareness about digital accessibility and inclusion for people with disabilities. Held every third Thursday in May, GAAD encourages individuals, businesses, and organizations to reflect on the importance of creating accessible digital experiences. While GAAD highlights the needs of people with disabilities, accessibility benefits everyone not just those with disabilities.
Drug Patent Watch
MAY 14, 2025
"The Prescription for Change: How PBM's are Ripping the Rhythm of the Pharmaceutical Industry Imagine a music industry where a single middleman controlled access to every song, dictating who could play them, when, and at what price. That's essentially the world of Pharmacy Benefit Managers (PBMs) in the pharmaceutical industry. In this exclusive article, we delve into the complex web of PBM's and their impact on the pharmacy landscape.
Predictive Oncology
MAY 14, 2025
In this white paper, Predictive Oncology (POAI) highlights a recent successful project in partnership with the University of Michigan Natural Products Discovery Core (NPDC) through the ACE program. The ACE program supports academic researchers in their early drug discovery and development initiatives by providing access to the POAI proprietary active machine learning platform and frozen patient DTC samples.
Science Daily: Pharmacology News
MAY 15, 2025
Many an orange cat-affiliated human will vouch for their cat's, let's say, specialness. But now scientists have confirmed that there is, in fact, something unique about ginger-hued domestic felines. In a new study, researchers have discovered the long-posited but elusive genetic mutation that makes orange cats orange -- and it appears to occur in no other mammal.
Drugs.com
MAY 15, 2025
THURSDAY, May 15, 2025 — The 2023 approval of the first drug shown to slow the progression of Alzheimer’s disease came with no small amount of concern from skeptics. Lecanemab (Leqembi) modestly slows Alzheimer’s by helping the.
Perficient: Drug Development
MAY 14, 2025
Considering migrating your contact center operations to the cloud? Transitioning from a legacy on-premise solution to a Cloud Contact Center as a Service (CCaaS) platform offers significant advantages, including greater flexibility, scalability, improved customer experience, and potential cost savings. However, the success of this transition depends heavily on selecting the right vendor and ensuring alignment with your unique business requirements.
Broad Institute
MAY 14, 2025
Benjamin Cravatt By Rose Circeo May 14, 2025 Benjamin Cravatt, Ph.D. Ben Cravatt is professor and Norton B. Gilula Chair of Chemical Biology in the Department of Chemistry at The Scripps Research Institute. His research group is interested in developing chemical proteomic technologies that enable protein and drug discovery on a global scale and applying these methods to characterize biochemical pathways that play important roles in human physiology and disease.
ProRelix Research
MAY 14, 2025
In the ever-advancing field of pharmaceutical development, regulations surrounding drug clinical trials in the United States serve a critical purpose. These frameworks are not merely bureaucratic hurdles; they exist to […] The post Regulations for Drug Clinical Trials in the USA: Challenges, Opportunities, and Whats Next appeared first on ProRelix Research.
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