Broad Institute

MAY 21, 2025

In 2007, Sadelain and Rivire treated their first patient with leukemia, and in 2009, published details on how they manufactured personalized CAR T cells to treat patients with aggressive leukemia. After their clinical results, their technology was licensed to Juno Therapeutics (later acquired by Bristol Myers Squibb.)

Therapies 119

Therapies FDA Approval Engineering Immune Response 119

The Pharma Data

OCTOBER 22, 2020

months (Vermorken et al, JCO 2007). Innate Pharma’s commercial-stage product, Lumoxiti, in-licensed from AstraZeneca in the US, EU and Switzerland, was approved by the FDA in September 2018. The activity of cetuximab as a single agent in recurrent and/or metastatic SCCHN is limited, with a 12.6%

Clinical Trials 40

Clinical Trials Trials Cell Biology Production 40

Codon

AUGUST 10, 2023

Credit: Bruce Wetzel and Harry Schaefer, NCI, NIH | License Progress in biology is arguably moving faster today than at any point in the course of human history. Engineered biology has profound potential to change how we live, but the field has become broad, bloated, nebulous. Nature Reviews Molecular Cell Biology (2009).

DNA 98

DNA Cell Biology Molecular Biology Engineering 98

Codon

AUGUST 10, 2023

Credit: Bruce Wetzel and Harry Schaefer, NCI, NIH | License Last edit: 13 September 2023 Progress in biology is arguably moving faster today than at any point in the course of human history. Engineered biology has profound potential to change how we live, but the field has become broad, bloated, nebulous. & Weiss R.

DNA 52

DNA Cell Biology Engineering Molecular Biology 52

BMG Labtech

FEBRUARY 24, 2025

Protein nitration assays are widely used in many research areas including but not limited to biochemistry , biotechnology , cell biology , microbiology , and molecular biology. 2007 Jul 15;75(2):291-302. 3 in this blog adapted from this reference under license CC-BY 4.0. Arch Pharm Res. 2009 Aug;32(8):1109-18.

Small Molecule 52

Small Molecule Disease Licensing Licensing 52