Bioinformatics Engineering Small Molecule 
The ChEMBL-og
JULY 10, 2025
ChEBI has for the past >20 years provided the biological community with access to definitive small molecule information and data, including accurate representations of often complex chemical structures.
Drug Target Review
JUNE 11, 2025
Unimodality does not allow for mixing data: cell data, images, molecular data, clinical data records, small molecule descriptors, ADME Tox data, transcriptomic data, text-based drug and disease representations, clinical trial protocols, publications and patent data, etc.
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Dark Matter Blog
AUGUST 31, 2020
The majority of small molecule drugs induce their therapeutic effects by seeking out and binding to their intended target while avoiding most other molecules in the dense milieu of the cell interior. Our overall mission at Arrakis is to expand the set of “druggable” targets for small-molecule medicines to include RNA.
Practical Cheminformatics
JANUARY 8, 2024
No member company will agree to use a representation that can potentially be reverse-engineered to reveal the chemical structures of its molecules. In each example, the authors use a modified version of their open source package MolPAL to design molecules with a specified selectivity profile.
Elrig
APRIL 29, 2024
With a background in Bioinformatics and Computational Biology, she has a keen interest in using technology to solve problems in healthcare and medicine. There, I supported AI-enabled DD efforts in their small molecule portfolio. Bioinformatics is all about bringing together different areas of knowledge.
Drug Target Review
SEPTEMBER 26, 2024
Cresset delivers software solutions and contract research expertise enabling companies around the world to accelerate their small molecule discovery processes efficiently and effectively. He also held a genomics consultancy role and worked as an R&D engineer in the speech-to-text domain at Hewlett Packard.
Codon
APRIL 16, 2023
Codon Digest is my weekly roundup of research, news, and industry highlights about engineered biology. These microbes were engineered to express tumor antigens that could “elicit T cells that were licensed by the commensal immune program but specific for a tumor,” including both CD4+ and CD8+ T cells, according to the study.
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