Broad Institute

MAY 21, 2025

The idea of genetically instructing T cells to specifically eliminate cancer cells was born in the 1980s, but it would take 20 years to bring it to patients, said Sadelain, who left MSKCC last year to become the Herbert and Florence Irving Professor of Medicine and director of the Columbia Initiative in Cell Engineering and Therapy.

Therapies 119

Therapies FDA Approval Engineering Immune Response 119

The Pharma Data

DECEMBER 1, 2020

Innate Pharma’s commercial-stage product, Lumoxiti, in-licensed from AstraZeneca in the US, EU and Switzerland, was approved by the FDA in September 2018. Lumoxiti is a first-in class specialty oncology product for hairy cell leukemia. About Innate Pharma: Innate Pharma S.A.

Cell Biology 52

Cell Biology Clinical Trials Production Licensing 52

The Pharma Data

JANUARY 4, 2021

This leads to activation and specific tumor-killing and cytokine secretion by NK cells, an immune cell population representing a significant proportion of all cytotoxic lymphocytes in the body.

Drugs 40

Drugs Cell Biology Pharmacokinetics Clinical Trials 40

The Pharma Data

OCTOBER 22, 2020

Innate Pharma’s commercial-stage product, Lumoxiti, in-licensed from AstraZeneca in the US, EU and Switzerland, was approved by the FDA in September 2018. Lumoxiti is a first-in class specialty oncology product for hairy cell leukemia. About Innate Pharma: Innate Pharma S.A.

Clinical Trials 40

Clinical Trials Trials Cell Biology Production 40

Codon

APRIL 2, 2023

This is Codon Digest, a weekly roundup of research papers, news articles, and industry highlights about engineered biology. ” — Samuel Butler , 1878 (* = My picks) AI + Bio Characterizing the interaction conformation between T-cell receptors and epitopes with deep learning. Thanks for skimming. Gungabeesoon J.

DNA 52

DNA RNA Engineering Licensing 52

Codon

APRIL 16, 2023

Codon Digest is my weekly roundup of research, news, and industry highlights about engineered biology. epidermidis , can actually trigger tumor-specific T cells. In other words: Brush some engineered bacteria on the skin, and they activate the immune system to go fight a tumor. Nature Cell Biology.

Engineering 52

Engineering DNA RNA Science 52

Codon

AUGUST 10, 2023

Credit: Bruce Wetzel and Harry Schaefer, NCI, NIH | License Progress in biology is arguably moving faster today than at any point in the course of human history. Engineered biology has profound potential to change how we live, but the field has become broad, bloated, nebulous. Nature Reviews Molecular Cell Biology (2009).

DNA 98

DNA Cell Biology Molecular Biology Engineering 98