Drug Target Review

JULY 3, 2025

Leveraging the extensive breadth of available data to identify entities and relationships across data sources, clinical research experts, therapeutic specialists, machine learning (ML) engineers and others can collectively evaluate areas of interest that may create new opportunities for the asset and a broader clinical strategy.

Drug Development

FDA Law Blog: Drug Discovery

NOVEMBER 10, 2024

FY2024 Awardees & Observations For the FY2024 Orphan Products Clinical Trials Grants Program, FDA received 51 grant applications and awarded only seven new clinical trials a grant, providing more than $17.2 million to clinical researchers over the next four years to advance the development of medical products for rare diseases.

Clinical Development

PPD

MARCH 11, 2025

Breaking through research barriers Challenge #1: Small groups of patients Rare diseases impact a small number of individuals, making it difficult to recruit enough participants for clinical trials. DCEs typically produce population-level estimates and require large samples to be robust.

Drug Development

Drug Target Review

APRIL 7, 2025

About the author Dr Cyril Clarke, Vice President, Therapeutic Area, GMI Drug Development and Consulting, ICON Biotech Clarke is a clinical pharmacologist with over 30 years experience in clinical research; seventeen of which are within industrial clinical pharmacology.

Clinical Development

PPD

NOVEMBER 11, 2024

Companies can benefit from solutions such as our Accelerator Drug Development, leveraging the combined strength of Thermo Fisher Scientific’s 360˚ Contract Development and Manufacturing Organization (CDMO) and Contract Research Organization (CRO) services , which provides CDMO, CRO and clinical trial supply chain capabilities that further streamline (..)

Drug Development

Drug Target Review

DECEMBER 16, 2024

In this interview, she discusses her path to becoming a physician and clinical researcher, the obstacles she faced, and her dedication to improving outcomes for cancer patients. Dr Hingorani also shares insights into the strengths women bring to STEM, the importance of mentorship, and her vision for the future of oncology research.

Medical Schools

PPD

JANUARY 15, 2025

About us The PPD clinical research business of Thermo Fisher Scientific , the world leader in serving science, enables our customers to accelerate innovation and increase drug development productivity.

Clinical Trials

PPD

FEBRUARY 10, 2025

In the past, these developers mostly used in-house resources for their clinical monitoring and site management capabilities, whereas today they often prefer functional service provider (FSP) or full-service outsourcing (FSO) models, or a hybrid of the two, to ensure on-time and on-budget delivery of clinical operations.

Clinical Trials

Drug Target Review

JULY 21, 2025

In Part 2 of our conversation with Layla Hosseini-Gerami, Chief Data Science Officer at Ignota Labs , we explore the many forms of toxicity and how AI-powered tools like omics and cell painting are transforming early prediction in pre-clinical research.

Drugs

Crown Bioscience

NOVEMBER 14, 2024

These innovations promise to enhance the precision and efficacy of early-stage research, setting a solid foundation for subsequent clinical applications and enabling the development of more personalized medicine.

Clinical Research

Conversations in Drug Development Trends

OCTOBER 14, 2024

Fortunately, advances in clinical research are providing hope for better treatments and outcomes. With the support of global networks like ours at Worldwide Clinical Trials (Worldwide), autoimmune and bone health research is accelerating, providing new solutions to patients around the world.

Research

Quanticate

JUNE 13, 2025

Clinical research generates vast amounts of diverse data from laboratory tests, patients, medical equipment, and outside sources. By organising and analysing this information, researchers can extract actionable insights that improve patient outcomes, data accuracy, drug efficacy and speed up trials.

Clinical Trials

Alta Sciences

DECEMBER 31, 2024

One of the most important factors to consider during the course of your early-phase clinical research is drug-drug interactions (DDIs), which occurs when one drug alters the effect of another, either by reducing its effectiveness or elevating systemic concentrations to potentially dangerous levelsultimately causing side effects.

Therapies

PPD

DECEMBER 16, 2024

The drug development industry faces rising costs and increasingly complex protocols as top challenges, with 49% of developers citing costs as their primary concern and 39% pointing to protocol complexity as a key hurdle, according to a recent survey of 150 drug developers worldwide by the PPD clinical research business of Thermo Fisher Scientific.

Drug Development

PPD

JULY 29, 2025

It also opens the door for sponsors to expand clinical research into emerging markets and remote areas with untapped patient populations and research sites with lower clinical trial activity. This expansion often leads to more consistent enrollment and increased staff engagement.

Clinical Trials

The Pharma Data

JUNE 15, 2025

Based on these data, it’s reasonable to expect that lonvo-z could enable patients to be free from both physical attacks and the daily burden of prophylactic treatments, offering them greater peace of mind and a significant improvement in their overall well-being.”

Treatment

Drug Target Review

MAY 23, 2025

I take responsibility for identifying pre-clinical research that can support our clinical programs, as well as designing and overseeing its execution, he explains. It takes a family to develop a drug Trembles role at Poolbeg is multifaceted, reflecting the collaborative ethos of the companys scientific team.

Immune Response

Broad Institute

NOVEMBER 25, 2024

Global Genes: RARE Concierge n-Lorem Foundation Genetic and Rare Disease Information Center Genetic Alliance My Gene2 Undiagnosed Diseases Network Rare Genomics Institute Rare Disease Clinical Research Network How can I sign up myself/my loved one to participate in clinical trials?

Clinical Trials

Advarra

DECEMBER 17, 2024

2024 has been a year of growth and evolution in clinical research. These topics include perspectives on how artificial intelligence (AI) will be leveraged in clinical research, key regulatory trends shaping the industry, the movements of site consolidation, the continued challenges (and potential solutions) of study startup, and more.

Clinical Research

PPD

JULY 18, 2025

The PPD clinical research business of Thermo Fisher Scientific is well-practiced at navigating complex regulatory relationships and has the global resources needed to achieve success, even across borders. The right CRO partner is often the key to approaching these strategies with the care and expertise they require.

Regulations

PPD

JUNE 17, 2025

This approach provides sponsors with the agility, efficiency and speed needed to expand clinical research into emerging markets or remote areas with highly qualified professionals in a cost-efficient manner.

Clinical Development

Advarra

MARCH 6, 2025

Institutional review boards (IRBs) play a crucial role in the ever-evolving field of clinical research. Innovations in fields such as immunotherapy, cancer and chronic diseases owe their existence to clinical trials, which judiciously test and evaluate safety and efficacy.

Clinical Research

Drug Target Review

MARCH 4, 2025

Phenomix Sciences, built on over a decade of clinical research at the Mayo Clinic, is disrupting this outdated approach. The research demonstrated that obesity is not one disease, but many; each of which should be treated with different interventions, says Bagnall.

Therapies

Advarra

JULY 3, 2025

10 areas that may impact your organization The third revision (R3) of the ICH E6 Guideline for Good Clinical Practice represents a significant modernization of global clinical research standards.

Compliance

Advarra

NOVEMBER 14, 2024

This collaborative spirit can lead to developing novel methodologies and strategies for monitoring and evaluating clinical trials, ultimately advancing the field of clinical research. This strategy is indispensable for advancing the clinical research field and ultimately improving patient outcomes across the globe.

Clinical Trials

PPD

JANUARY 2, 2025

FSP solutions are being more frequently utilized by biotech companies Biotech companies employ contract research organizations (CROs) to handle trial-related functions and services, often delivered through a full-service outsourcing (FSO) model, an FSP model or a mixed model combining both. FSP outsourcing is growing faster than FSO.

Clinical Development

KIF1A

JUNE 20, 2025

Take a look at quote from their partnership announcement below: The project represents a transformative step in expanding our understanding of KAND by incorporating continuous, real-world data collection into an already robust clinical research program.

Clinical Trials

The Pharma Data

JUNE 20, 2025

Dr. Jason Westin, Professor of Lymphoma and Director of Clinical Research at MD Anderson Cancer Center , remarked on the potential paradigm shift this combination could usher in: “There remains a clear need for effective and well-tolerated treatments for people with this difficult-to-treat disease.

Treatment

Quanticate

FEBRUARY 27, 2025

Wearable technologies have become a driving force in modern healthcare, transforming how data is collected, monitored, and analysed in clinical research.

Clinical Trials

Alta Sciences

JUNE 26, 2025

These technologies are helping pave the way toward more objective, reliable tools for clinical research. As these models continue to evolve in both accuracy and accessibility, they offer promise for clinicians seeking faster and more objective assessments in clinical and research settings.

Drug Development

The Pharma Data

JUNE 12, 2025

UCB and Biogen are continuing their extensive clinical research program to fully define dapirolizumab pegol’s role in SLE treatment. A second Phase 3 trial is currently underway to further validate these results and hopefully enable eventual submission to regulators for approval.

Disease

PPD

FEBRUARY 12, 2025

Its important for your clinical research organization (CRO) to continually assess and invest in capabilities that help drive the success of your clinical program. There are three core areas we are strategically addressing this year. They include: 1.

Clinical Supply

PPD

JUNE 20, 2025

Clinical science liaison (CSL): At the PPD clinical research business of Thermo Fisher Scientific, the CSL represents sponsors, interacting with sites from feasibility through recruitment. Thermo Fisher Scientific’s PPD clinical research business has extensive experience spanning many respiratory diseases, including IPF.

Clinical Development

Conversations in Drug Development Trends

NOVEMBER 5, 2024

In preparation for World Orphan Drug Congress Europe, we interviewed Nathan Chadwick, Senior Director, Therapeutic Strategy Lead, Rare Disease, and Derek Ansel, MS, LCGC, Vice President, Therapeutic Strategy Lead, Rare Disease, to hear their insights into the current progress in rare disease research and their hopes for 2025.

Disease

thought leadership

JULY 31, 2025

A  Contract Research Organization (CRO)  is a company that provides support to the pharmaceutical, biotechnology, and medical device industries in the form of research services outsourced on a contract basis. CROs offer a wide range of services, including:

Pharmaceuticals

Drug Target Review

MAY 5, 2025

He holds a BS in pharmaceutical sciences from the University of Mumbai and an MS in clinical research & administration from George Washington University, equipping him with the expertise to drive significant advancements in clinical research for a healthier tomorrow.

Clinical Development

PPD

APRIL 14, 2025

Expertise that accelerates your clinical development success The PPD clinical research business of Thermo Fisher Scientific has significant experience in customized Phase I-IV metabolic clinical trials. Were applying that expertise and commitment to every aspect of developing and running successful GLP-1 studies.

Clinical Trials