Drug Research and Drugs - Drug Discovery Digest

Millipedes make ants dizzy — and might soon treat human pain

Science Daily: Pharmacology News

JULY 25, 2025

Millipedes, often dismissed as creepy crawlies, may hold the secret to future painkillers and neurological drugs. Researchers at Virginia Tech discovered unique alkaloid compounds in the defensive secretions of a native millipede species.

Drug Research

Drug Research Therapies Drugs Research

Vera drug scores in closely watched study in rare kidney disease

BioPharma Drive: Drug Pricing

JUNE 2, 2025

Phase 3 results revealed Monday led shares to surge and should yield an approval application in IgA nephropathy, a competitive corner of drug research, later this year.

Disease

Disease Drugs Drug Research Research

Time for change: non-human primates in drug research

Drug Target Review

JULY 7, 2025

Non-human primates (NHPs), such as macaques and cynomolgus monkeys, have long served as a cornerstone in preclinical drug development due to their close genetic, anatomical and physiological resemblance to humans. Conventional models often fail to predict cardiac side effects, especially with biologics.

Drug Research

Drug Research Research Animal Testing Drugs

Machine Learning‐Based Discovery of a Novel Noncovalent MurA Inhibitor as an Antibacterial Agent

Chemical Biology and Drug Design

MARCH 12, 2025

Therefore, it is an important target for antibacterial drug research. In conclusion, through virtual screening and invitro biological evaluation, we identified a novel structural type of MurA inhibitor which may become a candidate drug for inhibiting bacterial cell wall synthesis.

Drug Research

Drug Research Research Drugs

Product Highlight: DrugBank on Snowflake Marketplace

DrugBank

OCTOBER 30, 2024

This lets you focus on what matters most: driving meaningful results in drug research and development. Your Need for Accessible, High-Quality Data—Solved Pharmaceutical research and healthcare innovation demand timely access to comprehensive, up-to-date data.

Production

Production Clinical Trials Packaging Compliance

"Pink Cocaine", Otherwise Known As Tusi

Common Sense for Drug Policy Blog

NOVEMBER 26, 2024

"Pink Cocaine", Otherwise Known As Tusi "The tusi phenomenon complicates the drug landscape because it has the potential to confuse both people who use and researchers alike. With respect to people who use, given the drug concoction’s name, people may assume the drug is 2C/2C-B.

Production

Production Drugs Science Drug Research

Texas Invests $50M in Psychedelic Drug Research into Ibogaine to Treat Addiction

Drugs.com

JUNE 16, 2025

MONDAY, June 16, 2025 — Texas has moved to fund research into ibogaine, a psychedelic drug that may help treat addiction, depression, and brain injuries. Greg Abbott signed a bill last week approving $50 million in state funds for.

Drug Research

Drug Research Research Drugs

Organon drug for endometriosis falls short in mid-stage study

BioPharma Drive: Drug Pricing

JULY 2, 2025

Deep Dive Library Events Press Releases Topics Sign up Search Sign up Search Pharma Biotech FDA Clinical Trials Deals Drug Pricing Gene Therapy An article from Dive Brief Organon drug for endometriosis falls short in mid-stage study Company executives had seen the drug as a potential multi-billion dollar opportunity in women’s health.

Clinical Trials

Clinical Trials Drugs Therapies Licensing

Sanofi to pour more than $20B into US drug research and manufacturing

BioPharma Drive: Drug Pricing

MAY 15, 2025

drug production, but cautioned plans could change amid shifting Trump administration policies. The French drugmaker joined several peers in promising new investments in U.S.

Drug Research

Drug Research Research Drugs Production

AltruBio lands up to $225M after shift to immune drug research

BioPharma Drive: Drug Pricing

MAY 21, 2024

Since pivoting from oncology, the startup has raised close to $300 million and advanced an ulcerative colitis drug into mid-stage testing.

Drug Research

Drug Research Research Drugs

FTC, in unusual move, leads Sanofi to terminate a drug research deal

BioPharma Drive: Drug Pricing

DECEMBER 12, 2023

Just before clearing Pfizer’s buyout of Seagen, the regulator threatened to block Sanofi’s licensing deal with Maze Therapeutics, a challenge the biotech called ‘‘unprecedented.”

Drug Research

Drug Research Licensing Licensing Research

Foundery, a new biotech venture firm, sets out to speed early immune drug research

BioPharma Drive: Drug Pricing

AUGUST 22, 2023

Billing itself as both a scientific and investment partner, Foundery aims to provide research grants and drug development support to researchers developing new immunotherapies.

Research

Research Drug Research Drug Development Drugs

Pfizer, looking for a jumpstart, leans into cancer drug research

BioPharma Drive: Drug Pricing

MARCH 1, 2024

Reeling from a difficult year financially, the pharma unveiled a new oncology division it says will produce eight billion-dollar medicines by 2030.

Drug Research

Drug Research Research Drugs

BioAge prices $198M IPO, validating pivot to obesity drug research

BioPharma Drive: Drug Pricing

SEPTEMBER 25, 2024

The offering, which was upsized twice, will support development of a drug the company believes can boost the effects of popular weight loss medicines like Eli Lilly’s Zepbound.

Drug Research

Drug Research Research Drugs

Pharmas form joint venture to jumpstart Japanese drug research

BioPharma Drive: Drug Pricing

APRIL 22, 2024

A new initiative backed by Takeda, Astellas and Sumitomo Mitsui Banking aims to combat a decade-long decline in drug R&D productivity in Japan.

Drug Research

Drug Research Research Drugs Production

FogPharma pulls in $145M to support cancer drug research

BioPharma Drive: Drug Pricing

MARCH 1, 2024

The cash will be used to advance development of FOG-001, the company’s lead drug that’s now being tested in an early-stage trial for solid tumors.

Drug Research

Drug Research Research Drugs Trials

Sanofi taps Belharra for immune drug research; AstraZeneca’s new cancer drug falls short

BioPharma Drive: Drug Pricing

JUNE 18, 2024

Belharra will use its chemoproteomics technology to identify immune drugs for Sanofi. Elsewhere, Regenxbio mapped a regulatory path and Taysha shared updated results for its Rett treatment.

Drug Research

Drug Research Drugs Research Treatment

Drug-Linked Disciplinary Actions by Schools Spiked After Oregon Legalized Marijuana

Drugs.com

OCTOBER 24, 2023

23, 2023 -- New research suggests a link between middle school students being disciplined for marijuana use and legalization of recreational weed, particularly when schools are close to dispensaries that sell the drug. Researchers. MONDAY, Oct.

Drugs

Drugs Drug Research Research

Startup Mariana raises $175M for radiopharmaceutical drug research

BioPharma Drive: Drug Pricing

SEPTEMBER 7, 2023

The Series B round makes Mariana one of the best funded private companies in a growing group of biotechs working on new radiopharmaceutical therapies.

Drug Research

Drug Research Research Therapies Drugs

Radiopharma startup Artbio raises $90M in sign of field’s momentum

BioPharma Drive: Drug Pricing

DECEMBER 7, 2023

The funding is indicative of investor interest in an area of drug research that involves at least a dozen startups and multiple publicly traded companies.

Drug Research

Drug Research Research Drugs

Backed by billionaires, a new biomedical institute tests an unorthodox approach

BioPharma Drive: Drug Pricing

JANUARY 12, 2024

Arena BioWorks, which will be led by Harvard University scientist Stuart Schreiber, seeks to blend academic and venture capital drug research models.

Drug Research

Drug Research Research Drugs

Pfizer to deepen cost cuts as latest sales forecasts miss expectations

BioPharma Drive: Drug Pricing

DECEMBER 13, 2023

The company is now expecting to save $4 billion by the end of 2024, with a majority of the spending cuts coming from drug research and development.

Drug Research

Drug Research Research Drugs

Medicare drug price cuts could have limited early impact, but grow with time

BioPharma Drive: Drug Pricing

AUGUST 16, 2024

Some industry watchers described the level of price discounts announced by Medicare as a "relief," though they warned of bigger future implications for drug research.

Drugs

Drugs Drug Research Research

Otsuka’s startup bet pays off with kidney disease drug results

BioPharma Drive: Drug Pricing

OCTOBER 22, 2024

A medicine the pharma acquired in a $430 million buyout of Visterra in 2018 succeeded in a Phase 3 trial in IgA nephropathy, a crowded corner of drug research.

Disease

Disease Drugs Drug Research Trials

Sarepta sells FDA fast pass earned from Duchenne gene therapy approval

BioPharma Drive: Drug Pricing

JULY 5, 2023

The deal enables Sarepta to quickly cash in on the clearance of Elevidys, with $102 million in new funds to help bankroll its drug research.

Therapies

Therapies FDA Drug Research Research

Astellas delves deeper into protein degrading drugs with Cullgen deal

BioPharma Drive: Drug Pricing

JUNE 14, 2023

The alliance is Astellas’ second recent partnership involving protein degraders, an emerging area of drug research the company has made a focus in recent years.

Drugs

Drugs Drug Research Research

Roche launches new Boston center; NIH centralizes peer review

BioPharma Drive: Drug Pricing

MARCH 7, 2025

The Swiss pharma will base cardiometabolic drug research at the new Allston site. Elsewhere, AskBio advanced a gene therapy and Pfizer hired a scientist well versed in GLP-1 science.

Science

Science Drug Research Therapies Research

Radiopharmaceuticals for cancer: Making radiation precise

BioPharma Drive: Drug Pricing

AUGUST 15, 2023

More than a dozen startups have joined a few publicly traded biotechs and larger pharmaceutical firms in what’s become one of the most competitive areas in drug research.

Drug Research

Drug Research Pharmaceuticals Research Drugs

Septerna raises $150M to fuel GPCR drug research

BioPharma Drive: Drug Pricing

JULY 11, 2023

RA Capital led a Series B financing round that drew participation from more than a dozen blue-chip venture backers, including new investors Goldman Sachs and Vertex Ventures.

Drug Research

Drug Research Research Drugs

5 questions facing pharma in 2025

BioPharma Drive: Drug Pricing

JANUARY 9, 2025

Political and economic uncertainty hangs over the industry, while major bets on metabolic and immune disease drug research are set to play out.

Drug Research

Drug Research Disease Research Drugs

Nexo allies with MD Anderson in pursuit of covalent cancer drugs

BioPharma Drive: Drug Pricing

JULY 26, 2023

The startup, which initially aims to make cancer medicines, claims to have a new twist on covalent drug research.

Drugs

Drugs Drug Research Research

Allogene taps Arbor in pursuit of ‘off-the-shelf’ CAR-T therapies for autoimmune disease

BioPharma Drive: Drug Pricing

MARCH 12, 2024

Allogene’s partnership with Arbor is designed to help the company stand out in what’s quickly become one of the industry’s hottest areas of drug research.

Therapies

Therapies Disease Drug Research Research

Can a Moderna co-founder change the CRO game?

BioPharma Drive: Drug Pricing

FEBRUARY 28, 2024

Well-known scientist and biotech entrepreneur Robert Langer is helping Lindus Health address longstanding challenges in contract drug research.

Drug Research

Drug Research Research Drugs

Will Walgreens’ store closures disrupt its clinical trial aims?

BioPharma Drive: Drug Pricing

NOVEMBER 22, 2024

Despite plans to shutter 1,200 stores, the company’s chief clinical trials officer said the pharmacy giant remains committed to aiding drug research.

Clinical Trials

Clinical Trials Trials Pharmacy Drug Research

Thermo Fisher to buy real-world evidence company CorEvitas for $913M

BioPharma Drive: Drug Pricing

JULY 6, 2023

The contract services provider, which secured the deal through a reportedly competitive process, expects CorEvitas to expand its drug research business.

Drug Research

Drug Research Research Drugs

Drug Channel Implications of the Inflation Reduction Act (NEW Live Video Webinar)

Drug Channels

MARCH 5, 2024

Fein, president of Drug Channels Institute (DCI) and the author of Drug Channels , invites you to join him for DCI’s latest live video webinar: Drug Channel Implications of the Inflation Reduction Act This event will be broadcast live on Friday, April 5, 2024, from 12:00 p.m. to 1:30 p.m. All rights reserved.

Pharmacy

Pharmacy Biosimilars Drugs Marketing

Possible adulticidal drugs for Onchocerca volvulus

Drug Target Review

SEPTEMBER 21, 2023

The research showed that exposing O. The findings supported the possibility put forward by Cotton et al (2016) concerning the chance of repurposing these drugs for adulticidal treatment. Need for adulticidal drugs More than 99 percent of countries worldwide has been affected by this disease. volvulus.

Drugs

Drugs Treatment Disease Research

Unlocking Undruggable Targets: Shifting Paradigms in Modern Drug Discovery

DrugBank

MAY 15, 2024

The road to developing effective drugs is fraught with both promise and challenge, particularly when it comes to what scientists call "undruggable" targets. The Evolution of Drug Discovery: From Dark Rooms to Precision Targets In the past, drug discovery often felt like a lucky guess.

Small Molecule

Small Molecule Molecular Biology Drugs Disease

A hybrid evaluation of the intestinal absorption performance of compounds from molecular structure

Chemical Biology and Drug Design

JULY 5, 2024

Abstract Intestinal absorption of compounds is significant in drug research and development. Then, the molecular dynamics simulation and molecular docking were utilized to study the mechanism of differences in intestinal absorption of drugs and investigate the role of molecular structure.

Drug Research

Drug Research Research Drugs

Preclinical vs. Clinical Biomarkers: Understanding Their Distinct Roles in Drug Development

Crown Bioscience

MARCH 14, 2025

The Importance of Biomarkers in Drug Development Biomarkers have become essential tools in modern drug discovery and development, enabling researchers to predict drug efficacy, monitor disease progression, and tailor treatments to specific patient populations.

Drug Development

Drug Development Clinical Trials Drugs Drug Research

eBook: Unlocking Undruggable Targets

DrugBank

AUGUST 20, 2024

The world of drug discovery is in a state of transformation, with advancements in biotechnology opening doors to new possibilities for targeting previously "undruggable" disease mechanisms. The Power of Drug Repurposing Explore the immense potential of drug repurposing as a strategy for targeting undruggable targets.

Therapies

Therapies Pharmaceuticals Disease Research

The Molecular Mechanism of Resveratrol in the Treatment of Chronic Rhinosinusitis Through a Combination of Network Pharmacology and In Vitro Validation

Chemical Biology and Drug Design

FEBRUARY 25, 2025

Together, the present study systematically clarified the possible mechanisms of RES in the treatment of CRS and provided new ideas for the drug research of this disease. A variety of results from cell experiments verified that RES can effectively inhibit the inflammation, oxidative stress and apoptosis of LPS-induced HNEpCs.

Treatment

Treatment Disease Drug Research Research

In vivo preclinical models for immune-mediated inflammatory disease drug development

Crown Bioscience

AUGUST 2, 2021

Continue reading to learn more about IMIDs and some of the challenges facing the field, and to review some in vivo preclinical models that can be used to guide IMID drug research and development.

Disease

Disease Drug Development Immune Response Drugs

Product Highlight: DrugBank Data Dictionary

DrugBank

SEPTEMBER 12, 2024

At DrugBank we’re committed to improving your daily research and drug development operations. Data Exploration If you’re venturing into a new area of drug research, the Data Dictionary helps you identify relevant data fields and understand their context.

Production

Production Government Research Packaging

Millipedes make ants dizzy — and might soon treat human pain

Vera drug scores in closely watched study in rare kidney disease

Trending Sources

Time for change: non-human primates in drug research

Machine Learning‐Based Discovery of a Novel Noncovalent MurA Inhibitor as an Antibacterial Agent

Product Highlight: DrugBank on Snowflake Marketplace

"Pink Cocaine", Otherwise Known As Tusi

Texas Invests $50M in Psychedelic Drug Research into Ibogaine to Treat Addiction

Organon drug for endometriosis falls short in mid-stage study

Sanofi to pour more than $20B into US drug research and manufacturing

AltruBio lands up to $225M after shift to immune drug research

FTC, in unusual move, leads Sanofi to terminate a drug research deal

Foundery, a new biotech venture firm, sets out to speed early immune drug research

Pfizer, looking for a jumpstart, leans into cancer drug research

BioAge prices $198M IPO, validating pivot to obesity drug research

Pharmas form joint venture to jumpstart Japanese drug research

FogPharma pulls in $145M to support cancer drug research

Sanofi taps Belharra for immune drug research; AstraZeneca’s new cancer drug falls short

Drug-Linked Disciplinary Actions by Schools Spiked After Oregon Legalized Marijuana

Startup Mariana raises $175M for radiopharmaceutical drug research

Radiopharma startup Artbio raises $90M in sign of field’s momentum

Backed by billionaires, a new biomedical institute tests an unorthodox approach

Pfizer to deepen cost cuts as latest sales forecasts miss expectations

Medicare drug price cuts could have limited early impact, but grow with time

Otsuka’s startup bet pays off with kidney disease drug results

Sarepta sells FDA fast pass earned from Duchenne gene therapy approval

Astellas delves deeper into protein degrading drugs with Cullgen deal

Roche launches new Boston center; NIH centralizes peer review

Radiopharmaceuticals for cancer: Making radiation precise

Septerna raises $150M to fuel GPCR drug research

5 questions facing pharma in 2025

Nexo allies with MD Anderson in pursuit of covalent cancer drugs

Allogene taps Arbor in pursuit of ‘off-the-shelf’ CAR-T therapies for autoimmune disease

Can a Moderna co-founder change the CRO game?

Will Walgreens’ store closures disrupt its clinical trial aims?

Thermo Fisher to buy real-world evidence company CorEvitas for $913M

Drug Channel Implications of the Inflation Reduction Act (NEW Live Video Webinar)

Possible adulticidal drugs for Onchocerca volvulus

Unlocking Undruggable Targets: Shifting Paradigms in Modern Drug Discovery

A hybrid evaluation of the intestinal absorption performance of compounds from molecular structure

Preclinical vs. Clinical Biomarkers: Understanding Their Distinct Roles in Drug Development

eBook: Unlocking Undruggable Targets

The Molecular Mechanism of Resveratrol in the Treatment of Chronic Rhinosinusitis Through a Combination of Network Pharmacology and In Vitro Validation

In vivo preclinical models for immune-mediated inflammatory disease drug development

Product Highlight: DrugBank Data Dictionary

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