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MONDAY, June 16, 2025 — Texas has moved to fund research into ibogaine, a psychedelic drug that may help treat addiction, depression, and brain injuries. Greg Abbott signed a bill last week approving $50 million in state funds for.
Just before clearing Pfizer’s buyout of Seagen, the regulator threatened to block Sanofi’s licensing deal with Maze Therapeutics, a challenge the biotech called ‘‘unprecedented.”
Billing itself as both a scientific and investment partner, Foundery aims to provide research grants and drug development support to researchers developing new immunotherapies.
Persistent challenges with NHP use Despite their biological relevance, using live NHPs in research poses several major challenges: Ethical concerns NHPs, due to their advanced cognition and social behaviour, are at the centre of ongoing ethical debates. Supply chain disruptions Availability is a critical bottleneck in NHP-based research.
Phase 3 results revealed Monday led shares to surge and should yield an approval application in IgA nephropathy, a competitive corner of drugresearch, later this year.
The offering, which was upsized twice, will support development of a drug the company believes can boost the effects of popular weight loss medicines like Eli Lilly’s Zepbound.
Belharra will use its chemoproteomics technology to identify immune drugs for Sanofi. Elsewhere, Regenxbio mapped a regulatory path and Taysha shared updated results for its Rett treatment.
The funding is indicative of investor interest in an area of drugresearch that involves at least a dozen startups and multiple publicly traded companies.
23, 2023 -- New research suggests a link between middle school students being disciplined for marijuana use and legalization of recreational weed, particularly when schools are close to dispensaries that sell the drug. Researchers. MONDAY, Oct.
RA Capital led a Series B financing round that drew participation from more than a dozen blue-chip venture backers, including new investors Goldman Sachs and Vertex Ventures.
The Swiss pharma will base cardiometabolic drugresearch at the new Allston site. Elsewhere, AskBio advanced a gene therapy and Pfizer hired a scientist well versed in GLP-1 science.
More than a dozen startups have joined a few publicly traded biotechs and larger pharmaceutical firms in what’s become one of the most competitive areas in drugresearch.
Therefore, it is an important target for antibacterial drugresearch. UDP-N-acetylglucosamine 1-carboxyethylene transferase (MurA) is an important enzyme involved in bacterial cell wall synthesis. Although many MurA inhibitors have been discovered, only fosfomycin is still used as a MurA inhibitor in clinical practice.
Some industry watchers described the level of price discounts announced by Medicare as a "relief," though they warned of bigger future implications for drugresearch.
At DrugBank, we’re dedicated to empowering pharmaceutical researchers with data that drives impactful results. Now, through our partnership with Snowflake, we’re making it even easier than ever for you to access high-quality, actionable data in a secure, and scalable environment designed to keep pace with your research needs.
A medicine the pharma acquired in a $430 million buyout of Visterra in 2018 succeeded in a Phase 3 trial in IgA nephropathy, a crowded corner of drugresearch.
Allogene’s partnership with Arbor is designed to help the company stand out in what’s quickly become one of the industry’s hottest areas of drugresearch.
The alliance is Astellas’ second recent partnership involving protein degraders, an emerging area of drugresearch the company has made a focus in recent years.
The contract services provider, which secured the deal through a reportedly competitive process, expects CorEvitas to expand its drugresearch business.
However, the effect of resveratrol on chronic rhinosinusitis (CRS) still lacks systematic research. Together, the present study systematically clarified the possible mechanisms of RES in the treatment of CRS and provided new ideas for the drugresearch of this disease.
Distinguishing the Roles of Preclinical vs. Clinical CROs in Clinical Research Randomized clinical trials are the gold-standard of evidence-based medicine, representing the culmination of the long, arduous drug development pipeline. What is a Pre-Clinical CRO? The global preclinical CRO market was estimated to be valued at US$5.7
Abstract Intestinal absorption of compounds is significant in drugresearch and development. The QSPR model accurately predicted the intestinal absorption of molecules, and the computer simulation found the mechanism of molecular structure affecting intestinal absorption.
The world of drug discovery is in a state of transformation, with advancements in biotechnology opening doors to new possibilities for targeting previously "undruggable" disease mechanisms. The Power of Drug Repurposing Explore the immense potential of drug repurposing as a strategy for targeting undruggable targets.
At DrugBank we’re committed to improving your daily research and drug development operations. It’s designed to fit naturally into your existing processes, enhancing your ability to collaborate with standardized definitions and focus on your research tasks.
Introduction I clearly remember an incident as a researcher, which kept happening, from my undergraduate research up till now. Summary of research The undergraduate study concentrated on the potential adulticidal effects of oral analgesics (acetaminophen, aspirin, and ibuprofen) on Onchocerca volvulus. doi: 10.1002/14651858.CD011146.pub2.
The Importance of Biomarkers in Drug Development Biomarkers have become essential tools in modern drug discovery and development, enabling researchers to predict drug efficacy, monitor disease progression, and tailor treatments to specific patient populations.
The Evolution of Drug Discovery: From Dark Rooms to Precision Targets In the past, drug discovery often felt like a lucky guess. Researchers would sift through natural extracts , hoping to stumble upon a compound that exhibited beneficial effects. In fact, it's one of the most exciting areas in drugresearch today.
Historically, many drugs have been prescribed to children even though this patient population have largely been excluded from clinical trials. There is an obvious logic. If medicines are to be used in children, they need to be studied in pediatric populations to ensure they are safe and effective.
There are many obstacles that you have to overcome on the road to success in early-stage drug discovery and drug repurposing research. As a result, the industry is turning to managed data sources and are having to weigh the costs and benefits of open data sources versus enterprise research tools.
Sygnature Discovery is delighted to announce that its customer, River BioMedics , has raised an additional €2M in seed funding to continue its life-saving cardiovascular drugresearch. The biotech’s aim is to develop medicines that treat the underlying cause of heart failure rather than merely treating the symptoms.
Continue reading to learn more about IMIDs and some of the challenges facing the field, and to review some in vivo preclinical models that can be used to guide IMID drugresearch and development.
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