Mon.Apr 08, 2024

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Vodcast: Dr Adriano Flora, The Jackson Laboratory

Drug Discovery World

The latest sponsored DDW Sitting Down With vodcast features Dr Adriano Flora, Director of Business Development at The Jackson Laboratory (JAX). He discusses alternatives to non-human primates, the key benefits of this, and what impact will they have on the future of drug development. Moreover, he answers questions on the key breakthroughs in recent years in this field and how have these impacted future success, as well as challenges in the clinic that must be overcome to ensure this success is a

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Psychiatry drugs finally have pharma’s attention. Can they keep it?

BioPharma Drive: Drug Pricing

Recent biotech company acquisitions have put emerging schizophrenia treatments in focus. But many development hurdles still stand in the way of new medicines for the brain.

Treatment 135
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Where is the opportunity in the therapeutic antibody market?

Drug Discovery World

In this free webinar, you will hear from Dr Jill O’Donnell-Tormey, CEO and Director of Scientific Affairs at Cancer Research Institute; Dr Roger Levy, Senior Global Medical Director, GSK Specialty Medicine; Dr Sheila Keating, VP of Immunology at Gigagen; as well as event sponsors Dr Milind Nigam, Leader – Scientific Solutions Consulting at Benchling, and Dr Paola Genevini, Technical Sales Specialist at Bio-Rad.

Marketing 147
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Pregnancy accelerates biological aging in a healthy, young adult population

Science Daily: Pharmacology News

Pregnancy may carry a cost, reports a new study. The research shows that women who reported having been pregnant looked biologically older than women who had never been pregnant, and women who had been pregnant more often looked biologically older than those who reported fewer pregnancies.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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News from AACR 2024: Sunday’s highlights

Drug Discovery World

The American Association of Cancer Research (AACR) Annual Meeting launched on Sunday 7 April in San Diego with an Opening Plenary Session showcasing cutting-edge technological advances opening new frontiers in cancer science. The session ‘Inspiring Science, Fueling Progress, Revolutionizing Care’ featured a distinguished panel of cancer scientists who described evolving and emerging technological advances – from cell atlases and artificial intelligence-based biomarkers to proteomics and bioortho

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Many Cancer Drugs Still Unproven 5 Years After Accelerated Approval

Drugs.com

MONDAY, April 8, 2024 -- New research questions the effectiveness of the U.S. Food and Drug Administration's accelerated drug approval program after finding that many cancer drugs remain unproven five years later.The study, published Sunday in the.

Drugs 116

More Trending

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Engineers design soft and flexible 'skeletons' for muscle-powered robots

Science Daily: Pharmacology News

Engineers designed modular, spring-like devices to maximize the work of live muscle fibers so they can be harnessed to power biohybrid robots.

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Where is the opportunity in the therapeutic antibody market?

Drug Discovery World

Join DDW for this free event ‘ Where is the opportunity in the therapeutic antibody market? ’, which is co-sponsored by Bio-Rad and Benchling. The event will take place on 30 April at 3PM BST / 4pm CEST / 10am EDT / 7am PDT. In this free webinar, you will hear from Dr Jill O’Donnell-Tormey, CEO and Director of Scientific Affairs at Cancer Research Institute; Dr Roger Levy, Senior Global Medical Director, GSK Specialty Medicine; Dr Sheila Keating, VP Immunology at Gigagen; as well as event

Marketing 130
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Therapeutic Vaccine Prevents Pancreatic Cancer's Recurrence in 3-Year Trial

Drugs.com

MONDAY, April 8, 2024 -- A pancreatic cancer vaccine has continued to protect a small group of patients from their cancer coming back, three years after receiving the jab, a new study says.Eight patients have not had their pancreatic cancer recur.

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€1.6m grant supports drug discovery in metabolic diseases

Drug Discovery World

Confo Therapeutics has been awarded a €1.6 million grant from Flanders Innovation & Entrepreneurship (VLAIO). The two-year grant will be used to expand Confo’s R&D efforts in the discovery of new medicines targeting Class B G protein-coupled receptors (GPCRs) using its patent-protected technology platform. Class B GPCRs are recognised as important targets for new medicines, particularly in chronic endocrine and metabolic diseases.

Disease 130
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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New study highlights the benefit of touch on mental and physical health

Science Daily: Pharmacology News

Through a large-scale analysis, researchers have uncovered the ways in which consensual touch can benefit a person's physical and mental wellbeing.

Research 120
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Charles River achieves 92% renewable energy use

Drug Discovery World

Charles River Laboratories has reported achieving 92% renewable energy usage worldwide in its 2023 Corporate Citizenship Report. The 2023 report evaluates the company’s progress across its strategic Environmental, Social and Governance (ESG) areas of focus: Accelerate Life-Saving Therapies; Lead with Integrity; Inspire our People; and Protect our Planet.

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Telescope detects unprecedented behavior from nearby magnetar

Science Daily: Pharmacology News

Captured by cutting-edge radio telescope technology, a chance reactivation of a magnetar -- the Universe's most powerful magnets -- has revealed an unexpectedly complex environment.

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Women want to participate in clinical trials. Lack of flexibility is still a problem.

BioPharma Drive: Drug Pricing

Underrepresentation of women in clinical trials affects the resulting drugs that become available later. Even small changes could boost participation.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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How the moon turned itself inside out

Science Daily: Pharmacology News

Linking analyses of the moon's gravity field with models of its earliest evolution, scientists tell a story of the moon turning itself inside out after it solidified from a primordial magma ocean. The process left behind a vestige of dense, titanium-rich material beneath its Earth-facing side that makes its presence known by gravity anomalies.

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Even a Little Secondhand Smoke Ups Odds for A-Fib

Drugs.com

MONDAY, April 8, 2024 -- Just a little exposure to secondhand smoke may increase your risk for the heart rhythm disorder atrial fibrillation (A-Fib), a new, large study suggests.

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How to move from diversity to inclusion in medical research

Antidote

Increasing racial diversity in clinical research is a common topic in the industry, and for good reason. The purpose of a clinical trial is to ensure that any new medications are safe and effective for the patient population, so it is of the utmost importance that studies have participant pools that reflect the diversity of real-world individuals.

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Vaccine-by-Mouth Could Replace Antibiotics in Fighting UTIs

Drugs.com

MONDAY, April 8, 2024 -- A new oral vaccine could prove a potential alternative to antibiotics for people with recurring urinary tract infections, a new study says.More than half of patients with recurring UTIs (54%) wound up infection-free for.

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A friendly pat on the back can improve performance in basketball

Science Daily: Pharmacology News

A free throw in basketball will have every eye glued to one person. It's an intensely stressful situation. A research team studied whether a friendly tap on the shoulder increases the odds of making a shot.

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Urine Test Could Cut Need for Painful Bladder Cancer Procedure

Drugs.com

MONDAY, April 8, 2024 -- A new urine test could spare bladder cancer survivors from a painful follow-up procedure needed to ensure their cancer hasn’t come back, researchers report.People who’ve gotten surgery for high-risk bladder cancer.

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Climate change threatens Antarctic meteorites

Science Daily: Pharmacology News

Antarctica harbors a large concentration of meteorites imbuing the icy continent with an unparalleled wealth of information on our solar system. However, these precious meteorites are rapidly disappearing from the ice sheet surface due to global warming, according to a new study.

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Immunotherapy Before Surgery Might Boost Pancreatic Cancer Survival

Drugs.com

MONDAY, April 8, 2024 -- Pancreatic cancer patients may do better if they receive an immunotherapy drug as well as chemotherapy in preparation for surgery, new research suggests.Pancreatic cancer is one of the toughest to treat. Only 12% of.

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Addgene's Website Update

addgene Blog

Starting today, you may notice some changes to our website ! Part of sharing science and making access to materials easier is improving the tools you use to share and access them. Addgene’s product, development, and content teams have made some changes to the look and feel of addgene.org. Some you’ll notice right away, while others may be less obvious — but every change is meant to make your experience on our website better so you can get the resources you need more easily.

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Scientists Develop Vaccine Against Lethal Xylazine, Often Mixed With Street Drugs

Drugs.com

MONDAY, April 8, 2024 (HealthDay news) -- A new vaccine might be able to block the toxic effects of the animal tranquilizer xylazine, which is being added to illicit drugs and increasing overdose risk.The vaccine trains the immune system to attack.

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Toothed whale echolocation organs evolved from jaw muscles

Science Daily: Pharmacology News

Genetic analysis finds evidence suggesting that acoustic fat bodies in the heads of toothed whales were once the muscles and bone marrow of the jaw.

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Today's Young Adults Are Aging Faster, and That Might Help Spur Cancers

Drugs.com

MONDAY, April 8, 2024 -- Younger generations are aging more rapidly, and this could be leading to an increased risk of cancer, a new study says.People born in or after 1965 are 17% more likely to be experiencing accelerated aging compared to.

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Mediterranean marine worm has developed enormous eyes

Science Daily: Pharmacology News

Scientists are amazed at the discovery of a bristle worm with such sharp-seeing eyes that they can measure up to those of mammals and octopuses. The researchers suspect that these marine worms may have a secretive language, which uses UV light only seen by their own species. The advanced vision of such a primitive creature helps to finally settle an epic debate about the evolution of eyes.

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Blood Test Spots Early Pancreatic Cancers With 97% Accuracy

Drugs.com

MONDAY, April 8, 2024 -- A blood test appears capable of detecting early-stage pancreatic cancers with up to 97% accuracy, a new study reports.

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Trial shows Wegovy can ease heart failure symptoms

BioPharma Drive: Drug Pricing

The results were the second time Novo has shown its weight loss treatment can help with the condition, and may help it secure broader use of the drug.

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Auto Draft

Drug Discovery World

The post Auto Draft appeared first on Drug Discovery World (DDW).

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Enhancing Sponsor Outcomes: The Power of In-House Clinical Assessment Support

Conversations in Drug Development Trends

By Rolana Avrumson, MS, Vice President of Clinical Projects, Clinical Assessment Technologies In the intricate world of clinical trials, the precision and reliability of clinical assessments stand as pivotal factors in determining a trial’s success. Expertly managed clinical assessments by a team with fastidious attention to detail optimizes precision and reliability and helps you successfully navigate the complex terrain of clinical research.

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SAVE THE DATE: Drug Channels Leadership Forum, March 17-19, 2025

Drug Channels

I am pleased to announce the inaugural Drug Channels Leadership Forum ! This unique, new event will be held from March 17 to 19, 2025, at the Turnberry Resort and Spa in Miami. The Leadership Forum will be an executive gathering where drug channel leaders can network and discuss key issues and challenges facing the commercial healthcare system. We intend to bring together people from the entire drug channel: pharmaceutical manufacturers, pharmacy benefit managers (PBMs), health plans, insurers,

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Private biotech funding ticks up as venture firms deploy cash

BioPharma Drive: Drug Pricing

Twenty-six drugmakers closed private fundraising rounds worth more than $100 million, according to HSBC data shared with BioPharma Dive.

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Does the Drug Shortage White Paper Fall Short?

FDA Law Blog: Biosimilars

By Kalie E. Richardson — The U.S. Department of Health and Human Services (HHS) recently published a White Paper on Policy Considerations to Prevent Drug Shortages and Mitigate Supply Chain Vulnerabilities in the United States —with input from several HHS stakeholders, including FDA, CMS, and the Administration for Strategic Preparedness and Response.

Drugs 59