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In the ever-evolving world of content management systems (CMS), there are many options to choose fromWordPress, Joomla, Drupal, and others. But for developers who love clean code, flexibility, and control, October CMS stands out as a modern, elegant solution built on the popular Laravel PHP framework. What is October CMS? October CMS is an open-source, free CMS that makes web building easier without compromising power or flexibility.
Gene editing disrupts Huntingtons mutation in mice By Allessandra DiCorato May 27, 2025 Breadcrumb Home Gene editing disrupts Huntingtons mutation in mice Making single-letter edits in stretches of repeated DNA stopped or reversed the genetic change that causes Huntingtons disease and Friedreichs ataxia. By Allessandra DiCorato May 27, 2025 Credit: Agnieszka Grosso, Broad Communications Related news More versatile and efficient base editor unlocks new gene-editing targets Researchers extend powe
Birgit Wilding, Lydia Woelflingseder, Anke Baum, Krzysztof Chylinski, Gintautas Vainorius, Neil Gibson, Irene C. Waizenegger, Daniel Gerlach, Martin Augsten, Fiona Spreitzer, Yukina Shirai, Masachika Ikegami, Sylvia Tilandyov, Dirk Scharn, Mark A. Pearson, Johannes Popow, Anna C. Obenauf, Noboru Yamamoto, Shunsuke Kondo, Frans L. Opdam, Annemarie Bruining, Shinji Kohsaka, Norbert Kraut, John V.
The startup is the latest beneficiary of investors’ appetite for protein-degrading technology, which offers a way to reach drug targets other technologies can’t.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
In todays world, the Internet of Things (IoT) is revolutionizing industries across the globe by connecting devices, systems, and people in ways that were once unimaginable. From smart homes to advanced manufacturing, IoT is creating new opportunities for innovation, efficiency, and data-driven decision-making. At the forefront of this transformation is Microsoft Azure, a cloud computing platform that has become a powerhouse for IoT operations.
TUESDAY, May 27, 2025 -- The U.S. Food and Drug Administration has approved Zoryve (roflumilast) topical foam 0.3 percent for the treatment of plaque psoriasis of the scalp and body in adult and pediatric patients 12 years of age and older.Through.
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
TUESDAY, May 27, 2025 -- The U.S. Food and Drug Administration has approved Zoryve (roflumilast) topical foam 0.3 percent for the treatment of plaque psoriasis of the scalp and body in adult and pediatric patients 12 years of age and older.Through.
The agency recommends manufacturers update their vaccines to target the JN.1 strain. At the same time, HHS head Robert F. Kennedy Jr. is removing guidance that healthy children and pregnant women receive COVID shots.
"Unlock Hidden Profits in Pharmaceutical R&D: A recent analysis of top-selling medications reveals that companies that closely monitor their competitors' patent portfolios are 3x more likely to achieve a higher return on investment in drug development. By staying one step ahead of the competition, can you revolutionize your approach to pharmaceutical innovation?
City will receive $46 million from Biogen under the alliance. Elsewhere, Angelini Pharma licensed a rare disease therapy and the FDA refused to review a Savara lung drug.
Is it time to go beyond classic design in oncology trials? jgrcic Tue, 05/27/2025 - 11:55 Tue, 05/27/2025 - 11:55 Resource Type Whitepaper Promotion Start Tue, 05/27/2025 - 12:06 Use of healthy volunteers in first-in-human trials with oncology small molecules. Can an alternative approach expedite clinical development of small molecule oncology drugs and benefit patients?
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
By Dr. Naomi Lowy, Principal Drug Regulatory Expert FDA recently announced, CEO Forums: An FDA Listening Tour to Engage Pharma CEOs. These are scheduled to take place in several cities on both coasts in June and July (Link here). This tour to engage with pharmaceutical and biotech CEOs is unprecedented. According to the announcement, Commissioner Makary will be holding these along with Principal Deputy Commissioner Sara Brenner, M.D., M.P.H and Director of FDAs Center for Biologics Evaluation a
Researchers have designed a liquid hydrogen storage and delivery system that could help make zero-emission aviation a reality. Their work outlines a scalable, integrated system that addresses several engineering challenges at once by enabling hydrogen to be used as a clean fuel and also as a built-in cooling medium for critical power systems aboard electric-powered aircraft.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
"The Patent Paradox: How Paragraph IV Challenges Are Disrupting the Pharmaceutical Industry As the pharmaceutical landscape continues to evolve, one thing is clear: the rules of the game have changed. Paragraph IV challenges, once a rare occurrence, have become a staple of the industry, with 2022 seeing a record number of filings. But what do these challenges mean for pharma executives, and how can they navigate this complex landscape to protect their intellectual property and stay ahead of
Scientists, who have spent more than a decade examining the impact of artificial light at night on the world's coasts and oceans, have shown that more than one-fifth of the global ocean -- an area spanning more than 75 million sq km -- has been the subject of ocean darkening over the past two decades. Ocean darkening occurs when changes in the optical properties of the ocean reduce the depth of its photic zones, home to 90% of all marine life and places where sunlight and moonlight drive ecologi
"The Dark Side of Prescription Prices: Uncovering the Hidden Costs of Pharma Procurement As the cost of prescription medications continues to skyrocket, patients and payers are left wondering: where's the money going? A closer look at the pharma procurement process reveals a complex web of hidden fees, opaque pricing, and inefficient practices that are driving up costs and hurting those who need care the most.
In the long battle to create an effective HIV vaccine, scientists have made a major leap forward. A new study shows that a series of vaccines can coax the immune system to produce powerful antibodies capable of blocking a wide range of HIV strains -- including those that are typically the hardest to stop.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Highlights From the 17th Minipig Research Forum, by Shant Jackson pmjackson Tue, 05/27/2025 - 18:06 I recently had the chance to attend the 17th Minipig Research Forum (MRF) in Amsterdamand what an experience! This was my first time attending the forum, and visiting the Netherlands! It was a fantastic opportunity to connect with fellow experts in the nonclinical research space about topics specific to miniature swine.
A new study reveals a concerning decline in self-reported mental health among mothers in the United States between 2016 and 2023. The study also found modest but measurable declines in self-reported physical health during the same period.
Engineers developed a fuel cell that offers more than three times as much energy per pound compared to lithium-ion batteries. Powered by a reaction between sodium metal and air, the device could be lightweight enough to enable the electrification of airplanes, trucks, or ships.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
TUESDAY, May 27, 2025 Vitamin D supplements might be a veritable Fountain of Youth, capable of slowing down a persons biological aging, a new study says.People taking daily vitamin D3 experienced less wear-and-tear on their telomeres, the pro.
How come you can't tickle yourself? And why can some people handle tickling perfectly fine while others scream their heads off? Neuroscientists argue that we should take tickle research more seriously.
TUESDAY, May 27, 2025 Dozens of staff at the U.S. National Institutes of Health (NIH) walked out of a recent town hall meeting after Director Dr. Jay Bhattacharya suggested the agency may have helped fund research that caused the COVID-19 p.
Researchers have a new hypothesis for how brain cells called astrocytes might contribute to memory storage in the brain. Their model, known as dense associative memory, would help explain the brain's massive storage capacity.
TUESDAY, May 27, 2025 Music legend Billy Joel has canceled tour dates through July 2026 after being diagnosed with a brain condition called normal pressure hydrocephalus (NPH).The 76-year-old singer announced Friday that his condition had w.
TUESDAY, May 27, 2025 — U.S. mothers are struggling with both their mental and physical health, a new study says. The percentage of mothers who report excellent mental health dropped 12 points between 2016 and 2023, from 38% to 26%.
Humans were making tools from whale bones as far back as 20,000 years ago, according to a new study. This discovery broadens our understanding of early human use of whale remains and offers valuable insight into the marine ecology of the time.
TUESDAY, May 27, 2025 -- The last thing a cancer patient might like to do is hit the treadmill or hop on an exercise bike, given how much the disease and its treatments drain a persons energy.But toughing through regular workouts can boost their o.
Scientists have produced the finest images of the Sun's corona to date. To make these high-resolution images and movies, the team developed a new 'coronal adaptive optics' system that removes blur from images caused by the Earth's atmosphere. Their ground-breaking results pave the way for deeper insight into coronal heating, solar eruptions, and space weather, and open an opportunity for new discoveries in the Sun's atmosphere.
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