Tue.Mar 04, 2025

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Novel stem cell therapy repairs 'irreversible' corneal damage in clinical trial

Science Daily: Pharmacology News

Results from a phase 1/2 clinical trial of a novel stem cell treatment for cornea injuries found 14 patients treated and tracked for 18 months had a more than 90% success rate at restoring the cornea's surface and improvements in vision. The procedure, called CALEC (cultivated autologous limbal epithelial cells) involves taking stem cells from a healthy eye, expanding it into a graft over several weeks, then transplanting it into a patient's damaged eye.

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Continuous Glucose Monitors Can Overestimate Blood Sugar Levels, Study Finds

Drugs.com

TUESDAY, March 4, 2025 -- Continuous blood glucose monitors have been promoted as potentially life-changing for people with diabetes -- allowing real-time updates on blood sugar levels without the need for repeated finger pricks.But a new.

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Heat from the sun affects seismic activity on Earth

Science Daily: Pharmacology News

Researchers explore the likelihood that Earth's climate, as affected by solar heat, plays a role in seismic activity. Using mathematical and computational methods, they analyzed earthquake data alongside solar activity records and surface temperatures on Earth and observed that when they included Earth surface temperatures into their model, the forecasting became more accurate, especially for shallow earthquakes.

Research 301
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Many Americans Unaware Of Links Between HPV And Cancers

Drugs.com

TUESDAY, March 4, 2025 -- Many Americans remain unaware of the cancer risk for both men and women posed by human papillomavirus (HPV), a new Ohio State University poll has found.Most people dont know much about HPV and its long-term cancer risks, a.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Breakthrough in clean energy: Palladium nanosheets pave way for affordable hydrogen

Science Daily: Pharmacology News

Hydrogen energy is widely recognized as a sustainable source for the future, but its large-scale production still relies on expensive and scarce platinum-based catalysts. In order to address this challenge, researchers have developed Bis(diimino)palladium coordination nanosheets (PdDI), a novel two-dimensional electrocatalyst that effectively facilitates the hydrogen evolution reactions while minimizing the use of precious metals like platinum, paving the way for affordable hydrogen production.

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World's critical food crops at imminent risk from rising temperatures

Science Daily: Pharmacology News

A new study offers a more precise picture of exactly where and how warming will affect our ability to grow food.

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Blocking PD-1 and VEGF: The bispecific cancer drugs that could best Keytruda

BioPharma Drive: Drug Pricing

Striking study results last year indicated a new type of medicine may improve on Merck’s dominant immunotherapy, spurring a wave of research practically overnight.

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NASA's Hubble finds Kuiper Belt duo may be trio

Science Daily: Pharmacology News

The puzzle of predicting how three gravitationally bound bodies move in space has challenged mathematicians for centuries, and has most recently been popularized in the novel and television show '3 Body Problem.' There's no problem, however, with what a team of researchers say is likely a stable trio of icy space rocks in the solar system's Kuiper Belt.

Research 301
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Race-Neutral Formulas Improve Asthma Detection in Black Children

Drugs.com

TUESDAY, March 4, 2025 -- Race plays a role in whether a child is quickly and accurately diagnosed with asthma, a new study suggests.Outdated and flawed studies previously led to the belief that white children had naturally higher lung function co.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Obesity: Researchers discover a cause of leptin resistance -- and how to reverse it

Science Daily: Pharmacology News

Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss.

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Hospital Admissions for Children With Flu Climbing Across the United States

Drugs.com

TUESDAY, March 4, 2025 -- Pediatric hospital admissions for influenza have been rising across the United States since the beginning of the year, according to the American Academy of Pediatrics (AAP).Pediatric influenza-related hospital admissions.

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Amphibians bounce-back from Earth's greatest mass extinction

Science Daily: Pharmacology News

Ancient frog relatives survived the aftermath of the largest mass extinction of species by feeding on freshwater prey that evaded terrestrial predators, academics have found.

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Vault Snack #29 – New Curve Fits for Plotting and Analysing Assay Data in CDD Vault

Collaborative Drug

Hello, CDD users, and Happy 2025! As we get started with this new year, CDD Support thought we would highlight the CDD Vault Curves feature set.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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PBM Industry Update: Trends, Challenges, and What's Ahead (NEW Live Video Webinar)

Drug Channels

Dr. Adam J. Fein, president of Drug Channels Institute (DCI) and the author of Drug Channels , invites you to join him for DCIs new live video webinar: PBM Industry Update: Trends, Challenges, and What's Ahead This event will be broadcast live on Friday, April 4, 2025, from 12:00 p.m. to 1:30 p.m. ET This page describes the event and explains how to purchase a registration.

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Chemo Causes Lasting Physical Decline In Breast Cancer Survivors

Drugs.com

TUESDAY, March 4, 2025 -- Breast cancer survivors treated with chemotherapy tend to suffer a longer-lasting decline in their physical health, compared to women who receive hormone therapy or other cancer treatments.Chemotherapy patients reported a.

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Can We Control Field-Level Security from Apex?

Perficient: Drug Development

Imagine you are building a Salesforce application and must ensure that users can only access specific fields based on their profiles or permission sets. You might wonder: can we control field-level security (FLS) from Apex? Explore this topic and understand the possibilities, challenges, and best practices. Understanding Field-Level Security in Salesforce Before we explore Apex, let’s first understand how Salesforce manages field-level security (FLS).

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Forging a Path Forward for Substance Abuse Potential Studies With the Cross-Company Abuse Liability Council By Beatrice Setnik, PhD

Alta Sciences

Forging a Path Forward for Substance Abuse Potential Studies With the Cross-Company Abuse Liability Council By Beatrice Setnik, PhD pmjackson Tue, 03/04/2025 - 20:10 Many of my colleagues and I are members of the Cross-Company Abuse Liability Council (CCALC), where I have been a co-chair for the past seven years, and a member for 15. The CCALC is a grassroots organization that was founded by several pharmaceutical industry members seeking clarity around the conduct of abuse and dependence potent

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Bad Meetings Can Leave You With a Productivity 'Hangover'

Drugs.com

TUESDAY, March 4, 2025 -- Bad meetings don’t just waste time -- they can leave workers with a "meeting hangover," new research shows. More than 90% of employees surveyed by the University of North Carolina at Charlotte said they sometimes.

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Sofinnova secures €1.2B for new biotech investments

BioPharma Drive: Drug Pricing

The funding can support investment in as many as 60 new life sciences companies, said Sofinnova chairman Antoine Papiernik.

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Obesity On The Rise Worldwide, Report Says

Drugs.com

TUESDAY, March 4, 2025 -- More than half of adults and a third of children and teens worldwide will be overweight or obese by 2050, a comprehensive global analysis has concluded.Overweight and obesity rates in adults, children and teens more than.

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Obesity care gets personalised: tailoring therapies with Phenomix

Drug Target Review

Obesity treatment is undergoing a major shift, much like the advances seen in cancer care. Phenomix Sciences , led by CEO Mark Bagnall, is using precision medicine to make treatments more targeted and effective. In this interview, Bagnall explains how this approach is improving patient outcomes and driving the development of better obesity drugs. A personalised approach to obesity treatment Traditional obesity treatments have often followed a one-size-fits-all model, despite mounting evidence th

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Coaches Are Abusive To 1 In 5 NCAA Athletes, Survey Finds

Drugs.com

TUESDAY, March 4, 2025 -- Yelling. Taunts. Insults. Harsh words. Physical violence.About 1 in 5 college athletes receive such abuse from their coaches, researchers report.Overall, nearly 19% of more than 3,300 athletes on National College Athletic.

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The Importance of Pharmacovigilance in Generic Drug Development

Drug Patent Watch

The Unseen Heroes of Generic Drug Development: Pharmacovigilance As a generic drug developer, you're no stranger to the challenges of bringing affordable medications to market. From navigating complex regulatory landscapes to ensuring the quality and safety of your products, every step of the process requires meticulous attention to detail. But have you ever stopped to think about the unsung heroes of generic drug development?

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Perficient Recognized for Salesforce Expertise: Helping Businesses Thrive

Perficient: Drug Development

Keeping up with the ever-evolving Salesforce ecosystem can feel overwhelming. New features, best practices, and technologies emerge constantly, making it tough to know where to focus. Thats where independent research from trusted industry analysts comes inhelping businesses identify top-performing partners that drive real results. Were excited to share that Perficient was recently recognized by a leading global technology research and advisory firm as a standout Salesforce ecosystem partner in t

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Neumora bids farewell to R&D head; Biohaven’s ‘one step forward, one step back’ data

BioPharma Drive: Drug Pricing

Robert Lenz is leaving the brain drug developer to “pursue other interests.” Elsewhere, Acelyrin rejected a bid by Concentra and Atara cut staff.

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7 Ways to Connect at Adobe Summit 2025

Perficient: Drug Development

Adobe Summit is the platform’s premier digital experience conference. This year it’s being held in Las Vegas at The Venetian Convention and Expo Center, March 18 20. Attending the conference is a great way to learn about the latest digital trends, connect with peers and experts from around the world, and explore Adobes vision for the future of AI-powered digital experiences.

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Using Client Centricity as Fuel for Innovative Biologics Development and Manufacturing Solutions

Fierce BioTech

Using Client Centricity as Fuel for Innovative Biologics Development and Manufacturing Solutions This paper provides experienced insights for biopharmaceutical professionals who are interested in optimizing their development and manufacturing processes without compromising on quality. It is a resource for process development scientists, analytical development specialists, manufacturing leads, biopharma executives, and anyone seeking insights into modern biologics manufacturing solutions. mgriffi

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Automate the Deployment of a Static Website to an S3 Bucket Using GitHub Actions

Perficient: Drug Development

Automating deployments is crucial for efficiency and reliability in today’s fast-paced development environment. GitHub Actions provides a seamless way to implement CI/CD pipelines, allowing developers to automate the deployment of static websites without manual intervention. In this blog, we will explore how to deploy a static website to an AWS S3 bucket using GitHub Actions.

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Why Sleep Gets Harder With Age And How To Sleep Better

Drugs.com

TUESDAY, March 4, 2025 -- Tossing and turning more as you age? You’re not alone -- and experts think they know why. Dr. Shelby Harris, a sleep psychologist in White Plains, N.Y., explained that stress, sleep structure and hormonal changes can.

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