Drug Target Review

MARCH 15, 2024

Advancements in genetic and protein engineering through technology innovation, automation, and more recently machine learning, have led to the development of more complex molecules such as bispecific antibodies and antibody drug conjugates. References Mistry RK, Kelsall E, Sou SN, et al. Budge JD, Knight TJ, Povey J, et al.

Engineering 105

Engineering Molecular Biology Protein Expression Medical Schools 105

Codon

AUGUST 10, 2023

Credit: Bruce Wetzel and Harry Schaefer, NCI, NIH | License Progress in biology is arguably moving faster today than at any point in the course of human history. Engineered biology has profound potential to change how we live, but the field has become broad, bloated, nebulous. Journal of Molecular Biology (1961).

DNA 98

DNA Cell Biology Molecular Biology Engineering 98

Codon

AUGUST 10, 2023

Credit: Bruce Wetzel and Harry Schaefer, NCI, NIH | License Last edit: 13 September 2023 Progress in biology is arguably moving faster today than at any point in the course of human history. Engineered biology has profound potential to change how we live, but the field has become broad, bloated, nebulous. Nature (2005).

DNA 52

DNA Cell Biology Engineering Molecular Biology 52

Codon

MAY 29, 2025

This class of drugs was engineered to mimic the body’s glucagon-like peptide-1 hormone (GLP-1), which decreases blood glucose levels by activating its receptor to signal the release of insulin. This is the step after the initial transcription of DNA into mRNA by RNA Polymerase II, the protein to which alpha amanitin binds.

Drugs 106

Drugs DNA RNA Laboratories 106