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Defense-Forward Biosecurity

Codon

Allison Berke makes the case for real-time DNA sequencing and AI tools to detect pathogens before they spread widely. Reading DNA The first step in detecting a novel pathogen is recognizing it as an anomaly amidst a noisy background of other material. After copying the DNA to form a big pool, each piece is sequenced.

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Is That DNA Dangerous?

Codon

Tessa Alexanian and Max Langenkamp build computational DNA screening tools for a living. But today, rapid advances in DNA synthesis have made it possible for would-be bioterrorists to make pathogens, rather than buy them. Credit: Alamy In a 2006 report , the U.S. This article concludes our mini-issue. Thanks for reading!

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The Codon Guide to Synthetic Biology

Codon

Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J. Link DNA Cost and Productivity Data, aka "Carlson Curves" , by Carlson R. Link Next-Generation DNA Sequencing Methods , by Mardis E.R. Link DNA synthesis technologies to close the gene writing gap , by Hoose et al.

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Reservoirs of Resistance

Codon

In 2006 , a landmark study by biochemist Gerry Wright and colleagues at McMaster University showed that nearly 500 randomly isolated soil-dwelling Streptomyces were, on average, resistant to 7 or 8 antibiotics. DNA is particularly durable, with a half-life measured in thousands of years — far outlasting bacterial cells.

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The Codon Guide to Synthetic Biology

Codon

Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J. Link DNA Cost and Productivity Data, aka "Carlson Curves" , by Carlson R. Link Next-Generation DNA Sequencing Methods , by Mardis E.R. Link DNA synthesis technologies to close the gene writing gap , by Hoose et al.

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