Drugs.com

JUNE 6, 2025

FRIDAY, June 6, 2025 — Immunotherapy combined with chemo can give people a fighting chance against stomach and esophageal cancers, a new clinical trial says.People treated with durvalumab and chemotherapy were much more likely to go into remission.

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Clinical Trials Trials 259

BioPharma Drive: Drug Pricing

JANUARY 2, 2025

Expected readouts in diabetes, cancer and depression headline a series of study results that could help the biotechnology sector regain its footing after a shaky year.

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Clinical Trials Trials 274

Drugs.com

MAY 5, 2025

MONDAY, May 5, 2025 An experimental drug might help people with uncontrolled high blood pressure, according to early clinical trial results.People taking lorundrostat experienced twice the decline in their systolic blood pressure than people t.

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Clinical Trials Drugs Trials 206

Drugs.com

FEBRUARY 4, 2025

4, 2025 -- The U.S. Food and Drug Administration (FDA) has approved the first-ever clinical trials testing pig kidney transplants in people with kidney failure, marking a major step forward in cross-species transplantation.Two. TUESDAY, Feb.

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Clinical Trials FDA Approval FDA Trials 244

Drugs.com

JUNE 6, 2025

FRIDAY, June 6, 2025 — A repurposed diabetes drug can be an effective tool against fatty liver disease, a new clinical trial has found.Dapagliflozin helped people reduce fat levels in their liver and avoid liver scarring that comes with the c.

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Disease Clinical Trials Drugs Trials 244

Advarra

DECEMBER 17, 2024

As we look to 2025, Advarra thought leaders have compiled predictions and perspectives on key topics shaping the industry. For example, AI tools can pull data from protocols and automatically update clinical trial management systems (CTMS), reducing manual entry errors and increasing workflow speed.

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Clinical Research Clinical Trials Trials Hospitals 98

FDA Law Blog: Drug Discovery

JANUARY 30, 2025

However, as we note in that post, the design, timing of initiation, and timely conduct of confirmatory trials are also important considerations in FDAs determination of whether accelerated approval is appropriate. This blog post focuses on interpreting these new authorities with respect to timely conduct of confirmatory trials.

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Drugs.com

JUNE 24, 2025

TUESDAY, June 24, 2025 — A new Chinese-developed GLP-1 weight loss drug could prove a new competitor to blockbuster drugs Ozempic/Wegovy and Zepbound, clinical trial results show. Ecnoglutide helped people lose between 9% to 13% of their body.

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Clinical Trials Drugs Trials 180

Drugs.com

MAY 5, 2025

MONDAY, May 5, 2025 Testing positive for leukemia actually saved the life of 51-year-old Jan Leahy, a business process owner from Wimbledon, England.Leahy benefitted from a clinical trial evaluating a new bone marrow test that can detect a p.

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Clinical Trials Trials 180

BioPharma Drive: Drug Pricing

OCTOBER 18, 2024

Detailed data from a Phase 2b/3 study of Merck’s treatment clesrovimab should support the company’s efforts to win approval by the 2025-2026 season.

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Hospitals Disease Trials Treatment 279

Drugs.com

MAY 5, 2025

MONDAY, May 5, 2025 — An experimental drug might help people with uncontrolled high blood pressure, according to early clinical trial results. People taking lorundrostat experienced twice the decline in their systolic blood pressure than.

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Clinical Trials Drugs Trials 174

Drugs.com

FEBRUARY 21, 2025

21, 2025 -- The health benefits of aggressive blood pressure control outweigh the potential risks for seniors, according to the latest results from a major clinical trial.About 85% of seniors treated to a target blood pressure of 120. FRIDAY, Feb.

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Trials 284

Drugs.com

JUNE 24, 2025

TUESDAY, June 24, 2025 — Weighted vests have been touted as a potential means of warding off osteoporosis while losing weight. The idea is that the extra weight will promote new bone growth even as people are walking or jogging to lose.

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Trials 225

Drugs.com

APRIL 1, 2025

TUESDAY, April 1, 2025 -- Fasting every other day can prompt more weight loss than simply cutting calories, a new clinical trial shows.People who undertook 4:3 intermittent fasting lost just under 8% of their body weight within a year, compared to.

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Clinical Trials Trials 180

Covalent Modifiers

JUNE 12, 2025

Keserű ACS Medicinal Chemistry Letters 2025 16 (6), 991-997 DOI: 10.1021/acsmedchemlett.4c00622 4c00622 The STAT family of transcription factors are important signaling hubs, with several of them, particularly STAT3, being emerging oncotargets already investigated in clinical trials. Ashraf, Elvin D.

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Small Molecule Clinical Trials DNA Trials 130

Alta Sciences

JULY 3, 2025

Altasciences At CPHI Americas 2025 pmjackson Thu, 07/03/2025 - 13:41 In the ever-changing drug development world, staying agile is essential to enabling more informed decisions, faster. This blog was originally published in July 2025. Image Thumbnail_Blog_Lisa-v2.jpg Tags Manufacturing and Analytical Services Weight 14

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Small Molecule Drug Development Pharmaceuticals Science 52

Drugs.com

JUNE 17, 2025

TUESDAY, June 17, 2025 — A diet meant to lower blood pressure also can be effective in treating type 2 diabetes after a few tweaks, a new clinical trial indicates.The DASH (Dietary Approaches to Stop Hypertension) diet effectively treated high b.

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Clinical Trials Trials 227

PPD

FEBRUARY 12, 2025

Reach out to us The post Enhancing Your Experience: What to Expect From Us in 2025 appeared first on PPD. Upgrading our technology stack Weve prioritized targeted improvements and new systems and tools that drive innovation, enhance efficiency, and improve site and patient relationships.

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Clinical Supply Clinical Trials Drug Development Clinical Research 69

Drugs.com

MARCH 3, 2025

MONDAY, March 3, 2025 -- More than a third of food-allergic kids were able to eat full servings of their trigger foods after treatment with an injectable asthma drug, new clinical trial findings report. In all, 36% of children treated with.

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Clinical Trials Drugs Trials Treatment 284

Covalent Modifiers

FEBRUARY 25, 2025

Gill Journal of Medicinal Chemistry 2025 DOI: 10.1021/acs.jmedchem.4c02313 Seamon, Matthew Holderfield, Xing Wei, Yongxian Zhuang, Yu Chi Yang, Jingjing Jiang, Yue Huang, Ruiping Zhao, Yun Ling, Zhican Wang, Michael Flagella, Zhengping Wang, Mallika Singh, John E. Knox, Robert Nichols, David Wildes, Jacqueline A. Smith, Elena S.

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Clinical Trials Treatment Trials 147

Drugs.com

JANUARY 24, 2025

24, 2025 -- People can reverse their type 2 diabetes through a combination of calorie cutting and medication, a small clinical trial says.Overweight and obese adults caused their diabetes to go into remission by following a. FRIDAY, Jan.

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Clinical Trials Trials 278

Covalent Modifiers

MAY 18, 2025

Nafizul Haque Kazi, Nikolas Klink, Kai Gallant, Gian-Marvin Kipka & Malte Gersch Nat Struct Mol Biol , 2025 [link] The mitochondrial deubiquitinase ubiquitin-specific protease (USP) 30 negatively regulates PINK1parkin-driven mitophagy.

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Engineering Regulations Small Molecule Clinical Trials 147

Drugs.com

MAY 1, 2025

THURSDAY, May 1, 2025 -- The cutting-edge weight-loss drug Ozempic/Wegovy can stop and even reverse fatty liver disease, a new clinical trial has found.Nearly twice as many people taking semaglutide stopped their fatty liver disease without further.

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Disease Clinical Trials Trials Drugs 277

Drugs.com

APRIL 9, 2025

WEDNESDAY, April 9, 2025 -- An experimental drug can help patients with advanced multiple sclerosis (MS) delay the progressive disability that comes with their disorder, a new clinical trial suggests.The drug, tolebrutinib, delayed disability.

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Clinical Trials Drugs Trials 268

Fierce BioTech

JUNE 24, 2025

Accelerate Clinical Trials with Methylation-Based ctDNA Detection Download now to learn from biopharma industry leaders about how methylation-based ctDNA detection for precise MRD and response monitoring can accelerate your clinical trials.

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Clinical Trials Trials DNA Disease 52

Science Daily: Pharmacology News

JANUARY 15, 2025

A phase 1 clinical trial of the treatment in healthy volunteers will begin in early 2025. The study found that Xenon gas inhalation suppressed neuroinflammation, reduced brain atrophy, and increased protective neuronal states in mouse models of Alzheimer's disease.

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Disease Clinical Trials Treatment Trials 283

New Drug Approvals

APRIL 11, 2025

2] Fitusiran was approved for medical use in the United States in March 2025. [2] 2] History The efficacy and safety of fitusiran were assessed in two multicenter, randomized clinical trials which enrolled a total of 177 adult and pediatric male participants with either hemophilia A or hemophilia B. [2] 26 March 2025.

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Clinical Trials FDA FDA Approval Trials 107

Drugs.com

FEBRUARY 5, 2025

5, 2025 -- The U.S. The approval was based on the results of three phase 3 trials of. WEDNESDAY, Feb. Food and Drug Administration has approved Symbravo (meloxicam and rizatriptan) for the acute treatment of migraine with or without aura in adults.

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FDA Approval Treatment FDA Trials 261

Drugs.com

MARCH 3, 2025

MONDAY, March 3, 2025 -- More than a third of food-allergic kids were able to eat full servings of their trigger foods after treatment with an injectable asthma drug, new clinical trial findings report.In all, 36% of children treated with.

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Clinical Trials Drugs Trials Treatment 241

Drugs.com

APRIL 28, 2025

MONDAY, April 28, 2025 -- Adults with peanut allergies can be safely treated using exposure therapy to increase their resistance, new clinical trial results show.More than two-thirds of participants (67%) gained the ability to tolerate at least.

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Therapies Clinical Trials Trials 233

Conversations in Drug Development Trends

APRIL 29, 2025

Unfortunately, this years event, scheduled for February 27-28, 2025, in Washington, DC, was abruptly postponed less than one week before it began. Thats why Worldwide Clinical Trials was committed to ensuring the rare disease community still had a space to share knowledge, resources, and support on Rare Disease Day 2025.

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Disease Clinical Trials FDA Trials 69

Drugs.com

APRIL 16, 2025

WEDNESDAY, April 16, 2025 -- A new clinical trial will soon test if a pig liver can help people whose own livers have suddenly stopped working.The hope? That animal organs can temporarily filter a patients blood, giving their own liver time to r.

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Trials Clinical Trials 130

The Pharma Data

JUNE 18, 2025

Many of these companies have used the grant as a springboard for clinical trials, regulatory approvals, and successful funding rounds. Merck has deliberately structured the program to not only recognize scientific excellence but to serve as a meaningful catalyst for translational development.

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Science Therapies Disease Treatment 40

The Pharma Data

JUNE 11, 2025

argenx Unveils Positive Phase 2 Results for Efgartigimod in Myositis and Sjogren’s Disease at EULAR 2025 argenx SE a global immunology company dedicated to advancing treatments for severe autoimmune diseases, presented encouraging new clinical data at the 2025 European Congress of Rheumatology (EULAR), held June 11–14 in Barcelona, Spain.

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Disease Treatment Trials Therapies 40

FDA Law Blog: Biosimilars

APRIL 13, 2025

By Sarah Wicks & Dara Katcher Levy FDAs Office of Prescription Drug Promotion (OPDP) issued its second Untitled Letter of 2025 to Taiho Oncology (Taiho) for a healthcare provider branded website for its drug LYTGOBI (futibatinib). As a single-arm trial (i.e., The problem?

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Drugs FDA Trials Treatment 52

The Pharma Data

JUNE 9, 2025

Cardiovascular Insights from the XYLO Trial One of the most notable late-breaking presentations was the Phase 4 XYLO study, which examined the cardiovascular benefits of switching patients from high-sodium, twice-nightly oxybate therapy to the same dosage of low-sodium Xywav over a six-week period. According to Dr. Richard J.

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FDA Approval FDA Pharmaceuticals Treatment 40

Broad Institute

APRIL 5, 2025

David Liu receives Breakthrough Prize in Life Sciences By Corie Lok April 5, 2025 Breadcrumb Home David Liu receives Breakthrough Prize in Life Sciences Liu is honored for the development of base editing and prime editing, two gene editing technologies transforming medicine.

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Science Clinical Trials DNA Disease 144