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Next Generation Sequencing (NGS): why is quantifying nucleic acids important? | BMG LABTECH

BMG Labtech

These numbers reflect impressive developments in DNA sequencing technologies but in most cases represent the immediate costs of consumables on the sequencing instrument. 2 DNA sequencing is also reliant on sample processing and DNA library preparation before sequencing as well as bioinformatics and data analysis after sequencing.

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Reaching cruising altitude: New discovery tools to target RNA

Dark Matter Blog

We stuck with our trusty aptamer system, but instead of running the DNA products made by RT on a gel, we attached them to adapters that enabled next-generation sequencing. With millions of DNA sequences, we could precisely measure the rate of RT pausing at each position of the RNA.

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Code breaking and the Human Genome Project

The Open Targets Blog

via Wikimedia Commons) Right: Copy of a DNA sequence faxed in 1989 from teams working on the Human Genome Project (from the Wellcome Collection archives, Image credit: Helena Cornu)  Assembling a team At the core of this of course were people to provide both the intellectual input and the perseverance to make things happen. Searls, D.B.

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Monkey Embryos Grow to 25 Days — No Womb Required

Codon

3/ Prime Editing Spree Prime editors can change DNA in ways that Cas9 — and even base editors — cannot. Known as a "search-and-replace" gene-editing tool, prime editors can delete or replace DNA up to 10,000 bases in length, or substitute one base for another. Read more in Cell. ( #1 , #2 ) (Video credit: Gong Y.

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Monkey Embryos Grow to 25 Days — No Womb Required

Codon

3/ Prime Editing Spree Prime editors can change DNA in ways that Cas9 — and even base editors — cannot. Known as a "search-and-replace" gene-editing tool, prime editors can delete or replace DNA up to 10,000 bases in length, or substitute one base for another. Read more in Cell. ( #1 , #2 ) (Video credit: Gong Y.

DNA 52
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Codon Digest: GPT-4 Controls a Robot

Codon

Short DNA strands were discovered that can specifically and tightly bind to zinc and cadmium ions. Perhaps there is now a way to use DNA to extract metals: You could fuse the DNA strands to an antibody, coat them onto electronics, and then use a column to isolate the DNA:metal compounds? BMC Bioinformatics. Mansilla S.F.

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The Codon Guide to Synthetic Biology

Codon

Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J. Link DNA Cost and Productivity Data, aka "Carlson Curves" , by Carlson R. Link Next-Generation DNA Sequencing Methods , by Mardis E.R. Link DNA synthesis technologies to close the gene writing gap , by Hoose et al.

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