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The only subject in school that held my interest was biology. As soon as I learned about DNA and RNA, I wanted to be a molecular biologist. I wanted to use molecularbiology to create drugs. Synta was focused on small molecule drug discovery and development in oncology and inflammatory diseases.
Sepofarsen has been granted orphan drug designation in the United States and the European Union and received fast-track designation and rare pediatric disease designation from the FDA as well as access to the PRIME scheme by the EMA. based Mogrify Limited expanded its research collaboration with MRC Laboratory of MolecularBiology.
Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Journal of MolecularBiology (1961). Link Mathematical modeling and synthetic biology , by Chandran D. Drug Discovery Today: Disease Models (2008). MolecularBiology of the Cell, 4th Edition.
The introduction of a nitro- group into a protein molecule is also implicated in different diseases including cardiovascular disease , lung disease, diabetes, cancer and some neurodegenerative conditions. While protein nitration is linked to disease, in many cases its precise physiological function is often unknown.
Ricin is toxic because it inactivates ribosomes, RNA-protein machines that translate each triplet codon of mRNA into its corresponding amino acid, linking them together to form peptides and proteins. This is the step after the initial transcription of DNA into mRNA by RNA Polymerase II, the protein to which alpha amanitin binds.
Link Gene Expression & Regulation →Genetic regulatory mechanisms in the synthesis of proteins , by Jacob F. & Journal of MolecularBiology (1961). Link Mathematical modeling and synthetic biology , by Chandran D. Drug Discovery Today: Disease Models (2008). MolecularBiology of the Cell, 4th Edition.
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