Drug Discovery World

JUNE 4, 2024

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The selected news highlights this week report breakthrough findings from early phase research and development, mainly preclinical studies and Phase I clinical trials, including a drug that can prevent sepsis deaths, a microbiome based immuno-oncology candidate, and a plant-based therapy

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Science Daily: Pharmacology News

JUNE 4, 2024

Have you ever wished you could understand what your dog is trying to say to you? Researchers are exploring the possibilities of AI, developing tools that can identify whether a dog's bark conveys playfulness or aggression.

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Research 139

Drug Discovery World

JUNE 4, 2024

The latest episode of the DDW Highlights podcast is now available to listen to below. DDW’s Megan Thomas narrates five key stories of the week to keep DDW subscribers up-to-date on the latest industry updates. The selected news highlights this week report breakthrough findings from early phase research and development, mainly preclinical studies and Phase I clinical trials, including a drug that can prevent sepsis deaths, a microbiome based immuno-oncology candidate, and a plant-based therapy

Clinical Trials 130

Clinical Trials Therapies Trials Research 130

BioPharma Drive: Drug Pricing

JUNE 4, 2024

A group of independent experts wasn't convinced by clinical trial data from company Lykos Therapeutics, which is seeking FDA approval of MDMA-assisted treatment for post-traumatic stress disorder.

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FDA FDA Approval Clinical Trials Therapies 130

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

JUNE 4, 2024

Phase II trial results have shown the superiority of immunotherapy pembrolizumab over chemotherapy when given before bowel cancer surgery. The results were presented by researchers at University College London (UCL) and UCLH at the American Society of Clinical Oncology (ASCO) Annual Meeting 2024. They are interim results from the NEOPRISM-CRC Phase II clinical trial in patients with stage two or stage three MMR deficient/MSI-High bowel cancer.

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Trials Hospitals Clinical Trials Treatment 130

Science Daily: Pharmacology News

JUNE 4, 2024

Adolescents with an internet addiction undergo changes in the brain that could lead to additional addictive behavior and tendencies, finds a new study.

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Science Daily: Pharmacology News

JUNE 4, 2024

Driven by an older, more diverse population, along with a significant increase in risk factors including high blood pressure and obesity, total costs related to cardiovascular disease (CVD) conditions are likely to triple by 2050, according to recent projections. At least 6 in 10 U.S. adults (61%), more than 184 million people, are expected to have some type of CVD within the next 30 years, reflecting a disease prevalence that will have a $1.8 trillion price tag in direct and indirect costs.

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Disease 123

Perficient: Drug Development

JUNE 4, 2024

Various deployment methods, including cloud-based (e.g., CloudHub) and on-premises, are available to meet diverse infrastructure needs. GitHub, among other tools, supports versioning and code backup, while CI/CD practices automate integration and deployment processes, enhancing code quality and speeding up software delivery. GitHub Actions, an automation platform by GitHub, streamlines building, testing, and deploying software workflows directly from repositories.

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Compliance Packaging Regulations 105

Science Daily: Pharmacology News

JUNE 4, 2024

Giant viruses found on the Greenland ice sheet probably regulate the growth of snow algae on the ice by infecting them. Knowing how to control these viruses could help us reduce the rate of ice-melt.

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Virus Regulations 113

Perficient: Drug Development

JUNE 4, 2024

Perficient is excited to announce our achievement in Amazon Web Services (AWS) DevOps Competency for AWS partners. This designation recognizes Perficient as an AWS partner that has demonstrated expertise in delivering Dev Sec Ops solutions. This competency highlights Perficient’s ability to drive innovation, meet business objectives , and get the most out of your AWS services.

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Clinical Trials

Science Daily: Pharmacology News

JUNE 4, 2024

Floating solar photovoltaic panels could supply all the electricity needs of some countries, new research has shown. The researchers calculated the daily electrical output for floating photovoltaics (FPV) on nearly 68,000 lakes and reservoirs around the world, using available climate data for each location.

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Research 120

Drug Channels

JUNE 4, 2024

It’s time for the annual update to Drug Channels Institute’s (DCI) analysis of pharmacist salaries and employment. 2023 was another tough year for pharmacists working in retail settings. While average salaries grew, they did not keep pace with overall inflation. Pharmacist employment at drug stores shrank but grew at supermarkets and mass merchants.

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Hospitals Drugs Pharmacy 98

Science Daily: Pharmacology News

JUNE 4, 2024

Study finds that mesalamine, a common anti-inflammatory drug, can fight the fungus Candida albicans in the gut, potentially preventing the risk of invasive candidiasis in patients with blood cancers.

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Drugs 113

Drugs.com

JUNE 4, 2024

TUESDAY, June 4, 2024 -- Could the blockbuster GLP-1 meds like Wegovy and Ozempic have a role to play in helping people cut down on problem drinking? A new study suggests so.Researchers at Case Western Reserve University in Cleveland report that.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Science Daily: Pharmacology News

JUNE 4, 2024

A team of palaeontologists has discovered a fossil of a gigantic flying reptile from the Jurassic period with an estimated wingspan of more than three metres -- making it one of the largest pterosaurs ever found from that era.

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addgene Blog

JUNE 4, 2024

Have you ever designed a CRISPR guide RNA and wondered why it is limited to only 20 bases, or why it’s so important to choose a target sequence with a nearby protospacer-adjacent motif (PAM) ? Cas9 is becoming an ever more ubiquitous tool for genome engineering, and studying its structure can help us understand the parameters of CRISPR experimental design.

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RNA Engineering 76

Science Daily: Pharmacology News

JUNE 4, 2024

Declining snowfall is changing the seasonal patterns of streamflow throughout the Northern hemisphere boosting chances of water shortages in the summer, scientists have found.

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Drugs.com

JUNE 4, 2024

TUESDAY, June 4, 2024 -- A company recall has been issued for cucumbers sold in 14 states because of possible contamination with salmonella.In a notice posted by the U.S. Food and Drug Administration, Florida-based Fresh Start Produce recalled the.

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Drugs 81

Science Daily: Pharmacology News

JUNE 4, 2024

Global warming caused by humans is advancing at 0.26 C per decade -- the highest rate since records began, according to new research by over 50 leading international scientists.

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International Research 110

Drugs.com

JUNE 4, 2024

TUESDAY, June 4, 2024 -- Artificial intelligence (AI) can improve doctors’ assessments of mammograms, accurately detecting even the smallest breast cancers with fewer scary false positive readings, a new study shows.AI-assisted mammography detected.

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Doctors 81

Science Daily: Pharmacology News

JUNE 4, 2024

Researchers have discovered sustained hunting by humans prevented the woolly rhinoceros from accessing favourable habitats as Earth warmed following the Last Ice Age.

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Research 113

Drugs.com

JUNE 4, 2024

TUESDAY, June 4, 2024 -- Folks with sleep apnea are more likely to require hospitalization for an ailment, a new study shows.People aged 50 and older with sleep apnea have 21% higher odds of hospitalization compared to those without the breathing.

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Hospitals 80

ASPET

JUNE 4, 2024

Patients with arthritis report using cannabis for pain management, and the major cannabinoid 9 -THC has anti-inflammatory properties, yet the effects of minor cannabinoids on arthritis are largely unknown. The goal of the present study was to determine the antiarthritic potential of the minor cannabinoid 8 -THC using the collagen-induced arthritis (CIA) mouse model.

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Treatment Production Disease 74

Drugs.com

JUNE 4, 2024

TUESDAY, June 4, 2024 -- Maternal mortality rates in the United States continue to exceed those in other wealthy nations, with most women dying during pregnancy and childbirth in ways that were preventable, a new report shows.In 2022, U.S. women.

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BioPharma Drive: Drug Pricing

JUNE 4, 2024

Longer follow-up results from a mid-stage trial indicate the company’s treatment for a genetic cause of dwarfism may be competitive to an approved therapy from BioMarin Pharmaceutical.

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Pharmaceuticals Therapies Trials Treatment 67

Drugs.com

JUNE 4, 2024

TUESDAY, June 5, 2024 -- Following the end of temporary pandemic-era rules expanding access to Medicaid, about 10 million Americans have lost that coverage.But a new report finds that most folks who've lost coverage have done so because of.

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Science Daily: Pharmacology News

JUNE 4, 2024

A new study found that drowsy driving by teenagers is a common threat to public safety on U.S. roadways.

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Drugs.com

JUNE 4, 2024

TUESDAY, June 4, 2024 -- Kids who spend more than six hours a day on their duffs have a greater risk of severe fatty liver disease and liver cirrhosis by the time they’re young adults, a new study claims.Children have 15% higher odds of fatty l.

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Disease 75

Drug Patent Watch

JUNE 4, 2024

Brivaracetam is the generic ingredient in two branded drugs marketed by Ucb Inc, Aurobindo Pharma Ltd, Lupin Ltd, Sunshine, and Zydus Pharms and, and is included in seven NDAs.

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Drugs Marketing 59

Drugs.com

JUNE 4, 2024

TUESDAY, June 4, 2024 -- Menopause before the age of 40 could raise a woman's long-term risk for breast or ovarian cancers, new research suggests. Besides that, "there is also higher risk of breast, prostate and colon cancer in relatives of these.

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Research 75

Drug Patent Watch

JUNE 4, 2024

Dabigatran etexilate mesylate is the generic ingredient in two branded drugs marketed by Alkem Labs Ltd, Apotex, Hetero Labs Ltd Iii, and Boehringer Ingelheim and, and is included in five… Source

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Drugs Marketing 59

Drugs.com

JUNE 4, 2024

TUESDAY, June 4, 2024 -- Booze could threaten a sleeping air passenger’s heart health, particularly on long-haul flights, a new study warns.Alcohol combined with cabin pressure at cruising altitude lowers the amount of oxygen in the blood and r.

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Drug Patent Watch

JUNE 4, 2024

ILEVRO (nepafenac) Harrow eye Patent: 7,947,295 Expiration: Jun 8, 2024 See More … For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.

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Pharmaceuticals Drugs 59

Drugs.com

JUNE 4, 2024

TUESDAY, June 4, 2024 -- The popular prebiotic sodas known as Poppi may not be quite as good for your gut as the company claims.In a class-action lawsuit filed last week in U.S. District Court in San Francisco, Kristin Cobbs said she bought Poppi.

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