Drug Discovery World

SEPTEMBER 12, 2024

New research has shown that Ellorarxine, a novel drug compound developed by biotech Nevrargenics, provides a robust neuroprotective effect and reduces neuronal death in cell models of neurodegenerative disease. The peer reviewed study published in Frontiers in Neuroscience was conducted by academics at Aberdeen and Durham Universities in the UK. Based on the results, the company has secured approval from the Medicines and Healthcare products Regulatory Agency (MHRA) to run a human study in the

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BioPharma Drive: Drug Pricing

SEPTEMBER 12, 2024

The offerings by Bicara, Zenas and MBX give a glimpse into what industry insiders describe as a backlog of mature startups waiting for the right opportunity to test public markets.

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Drug Discovery World

SEPTEMBER 12, 2024

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business. In this episode, Megan Thomas is in conversation with Dr Friso Postma, Vice President of AI Drug Discovery at BioXcel Therapeutics. Thanks to BioXcel’s AI platform, the company was able to repurpose previous drugs to obtain FDA approval for its acute treatment for agitation associated with schizophr

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Science Daily: Pharmacology News

SEPTEMBER 12, 2024

A landslide in a remote part of Greenland caused a 200 meter (650 foot) mega-tsunami that sloshed back and forth across a fjord for nine days, generating vibrations throughout Earth, according to a new study. The study concluded that this movement of water was the cause of a mysterious, global seismic signal that lasted for nine days and puzzled seismologists in September 2023.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drug Discovery World

SEPTEMBER 12, 2024

Glasgow, UK-based ILC Therapeutics has successfully completed a fundraise of £2.5 ($3.2) million. The company develops hybrid interferons, a new drug class engineered for improved therapeutic profiles across multiple indications. The money will support the continued pre-clinical development of the company’s two lead assets, Alfacyte and Dermacyte, as they move towards the clinic.

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Drugs.com

SEPTEMBER 12, 2024

THURSDAY, Sept. 12, 2024 -- It could be a real breakthrough for people at risk for HIV infection: A shot given every six months that reduces their risk by a whopping 96%.That's according to new trial results released Thursday by Gilead Sciences.

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Science Daily: Pharmacology News

SEPTEMBER 12, 2024

Our planet will only remain able to provide even the most basic standard of living for everyone in the future if economic systems and technologies are dramatically transformed and critical resources are more fairly used, managed and shared, a new report shows.

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Drug Discovery World

SEPTEMBER 12, 2024

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business. In this episode, Megan Thomas is in conversation with Dr Friso Postma, Vice President of AI Drug Discovery at BioXcel Therapeutics. Thanks to BioXcel’s AI platform, the company was able to repurpose previous drugs to obtain FDA approval for its acute treatment for agitation associated with schizophr

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FDA Approval Drugs FDA Science 130

BioPharma Drive: Drug Pricing

SEPTEMBER 12, 2024

Spun out of research at Nationwide Children’s Hospital, Vironexis claims it will be the first company to start a study testing a cancer drug delivered via the adeno-associated viruses commonly used in genetic medicines.

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Therapies Virus Trials Hospitals 112

Science Daily: Pharmacology News

SEPTEMBER 12, 2024

Researchers can harvest protein and vitamin B9 from microbes by feeding them nothing much more than hydrogen, oxygen, and CO2. The technology runs on renewable energy to produce a sustainable, micronutrient-enriched protein alternative that may one day make it to our plates.

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Research 111

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drugs.com

SEPTEMBER 12, 2024

THURSDAY, Sept. 12, 2024 -- Ozempic and Wegovy can prevent heart problems in overweight and obese people, particularly if they also suffer from kidney disease, a new clinical trial shows.The drugs’ active ingredient, semaglutide, reduced heart h.

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Science Daily: Pharmacology News

SEPTEMBER 12, 2024

Mega ocean warming El Nino events were key in driving the largest extinction of life on planet Earth some 252 million years ago, according to new research. The study has shed new light on why the effects of rapid climate change in the Permian-Triassic warming were so devastating for all forms of life in the sea and on land.

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Research 106

Drugs.com

SEPTEMBER 12, 2024

THURSDAY, Sept. 12, 2024 -- Prescriptions for amphetamine stimulants to treat ADHD have increased significantly in recent years, particularly during the pandemic.Unfortunately, high doses of stimulants like Adderall can increase the risk of.

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Science Daily: Pharmacology News

SEPTEMBER 12, 2024

Without immediate action, humanity will potentially face further escalation in resistance in fungal disease, a group of scientists from the around the world has warned. According to the scientists most fungal pathogens identified by the World Health Organization -- accounting for around 3.8 million deaths a year -- are either already resistant or rapidly acquiring resistance to antifungal drugs.

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Disease Drugs 101

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

SEPTEMBER 12, 2024

THURSDAY, Sept. 12, 2024 -- The injectable weight-loss drug Zepbound appears to work better in women than in men, according to a new analysis of the clinical trials that led to its approval.All doses of tirzepatide consistently reduced weight in.

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Clinical Trials Drugs Trials 105

Science Daily: Pharmacology News

SEPTEMBER 12, 2024

Could invisibility cloaks become a reality? New research brings this science fiction concept a step closer, with a breakthrough software package that simulates how waves interact with complex materials.

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Drugs.com

SEPTEMBER 12, 2024

THURSDAY, Sept. 12, 2024 -- An ingredient in the hair dye a French woman used caused her to develop a vision-robbing retinopathy, researchers report. When she switched to a dye without these ingredients, called aromatic amines, her vision troubles.

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Research 105

Science Daily: Pharmacology News

SEPTEMBER 12, 2024

A sweeping global research review of the links between climate and agriculture reveals the likelihood of an emergent feedback loop whereby, as climate change puts more pressure on the global food supply, agriculture will, by necessity, adopt practices that may exacerbate its environmental impact. The paper also identifies new agricultural practices that have the potential to increase efficiency and stabilize our food supply in the decades to come.

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Research 97

Drugs.com

SEPTEMBER 12, 2024

THURSDAY, Sept. 12, 2024 -- Statistics from 2023 on U.S. obesity rates bring no good news: In every state in the nation, 1 in every 5 people is now obese, the new tally shows.In 2013, not one state had an adult obesity rate topping 35%, but 10.

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BioPharma Drive: Drug Pricing

SEPTEMBER 12, 2024

The biotech will now suspend development of a drug prospect that Sanofi acquired partial rights to just four months ago.

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Drugs 116

Drugs.com

SEPTEMBER 12, 2024

THURSDAY, Sept. 11, 2024 -- Two monoclonal antibody treatments to slow Alzheimer's disease, lecanemab (Leqembi) and donanemab (Kisunla), have been approved by the U.S. Food and Drug Administration over the past two years. It's thought the drugs.

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Science Daily: Pharmacology News

SEPTEMBER 12, 2024

A research team has made a major discovery by designing molecules that could revolutionize computing.

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Research 121

Drugs.com

SEPTEMBER 12, 2024

THURSDAY, Sept. 12, 2024 -- A lot of Americans are on the fence regarding annual flu and COVID shots, a new survey finds.More than one-third of those polled (37%) said they’d gotten vaccines in the past but don’t plan to this year, according to res.

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Science Daily: Pharmacology News

SEPTEMBER 12, 2024

Researchers have shown unprecedented control of SIV replication and decay of viral reservoirs by combining a stringent model of infection with the interruption of antiretroviral therapy (ART). The success of this immune-based approach follows the research team's identification of the mechanisms of action for PD1 and IL-10, molecules known to regulate HIV persistence and immune dysfunction.

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Drugs.com

SEPTEMBER 12, 2024

THURSDAY, Sept. 12, 2024 -- Less than half of people who've survived a stroke will go on to have a healthy, normal sleep pattern, new research shows.Normal sleep is defined as six to eight hours of shuteye nightly. However, a majority of the.

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Research 98

Science Daily: Pharmacology News

SEPTEMBER 12, 2024

A new study finds that a trilobite species with exceptionally well-preserved fossils from upstate New York has an additional set of legs underneath its head. The research suggests that having a fifth pair of head appendages might be more widespread among trilobites than once thought and helps researchers better understand how trilobite heads are segmented.

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Research 82

Drugs.com

SEPTEMBER 12, 2024

THURSDAY, Sept. 12, 2024 -- The number of Americans with a potentially dangerous heart rhythm condition is three times greater than previously thought, a new study claims.An estimated 5% of the population -- 10.5 million U.S. adults -- have atrial.

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Science Daily: Pharmacology News

SEPTEMBER 12, 2024

Extreme conditions prevail inside stars and planets. The pressure reaches millions of bars, and it can be several million degrees hot. Sophisticated methods make it possible to create such states of matter in the laboratory -- albeit only for the blink of an eye and in a tiny volume. So far, this has required the world's most powerful lasers, and the opportunities for experiments are correspondingly rare.

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Laboratories Research 81

Drugs.com

SEPTEMBER 12, 2024

THURSDAY, Sept. 12, 2024 -- Black stroke victims are arriving at emergency rooms much later than white patients, greatly increasing their risk of death or lifelong disability, a new study finds.Every second counts when it comes to treating a.

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Science Daily: Pharmacology News

SEPTEMBER 12, 2024

Researchers have discovered why lithium-ion batteries, which power most electronic devices, lose capacity overtime. The findings could enable the development of electric vehicles that go far longer without needing a charge.

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Research 81

DrugBank

SEPTEMBER 12, 2024

At DrugBank we’re committed to improving your daily research and drug development operations. Our latest enhancement, the DrugBank Data Dictionary, is designed to streamline how you interact with our extensive data offerings. This tool is designed to bring clarity and precision to your workflows, enabling you to navigate our knowledgebase with ease and confidence.

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Science Daily: Pharmacology News

SEPTEMBER 12, 2024

Astronomers have directed NASA's James Webb Space Telescope to examine the outskirts of our Milky Way galaxy. Scientists call this region the Extreme Outer Galaxy due to its location more than 58,000 light-years away from the Galactic Center. (For comparison, Earth is approximately 26,000 light-years from the center.

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Drug Patent Watch

SEPTEMBER 12, 2024

In the labyrinthine world of pharmaceuticals, where the cost of life-saving medications can often feel like a roll of the dice, the FDA is implementing a strategy that aims to bring some much-needed transparency and affordability to the market. This strategy, known as the ‘Rule of Three,’ is a game-changer in the battle against soaring drug prices.

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Science Daily: Pharmacology News

SEPTEMBER 12, 2024

Hundreds of gamma-ray bursts (GRBs) have been recorded as part of an enormous global effort so extensive it 'rivals the catalog of deep-sky objects created by Messier 250 years ago', astronomers say. GRBs are the most violent explosions in the Universe, releasing more energy than the Sun would in 10 billion years. They occur when either a massive star dies or two neutron stars merge.

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