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In 2003, the completion of the Human Genome Project was celebrated as the start of a new era in medicine. However, even though genome sequencing can now be completed in a single day at a fraction of the original cost, and despite the exponential increase in data generation, nearly two decades later the clinical impact of genomics has been limited. The problem is not a lack of genetic insight; instead, biological processes operate on a level that goes far beyond genetic sequences.
Magazine ENEWS SUBSCRIBE WEBINARS PODCASTS EBOOKS ABOUT US Edit submissions Media kit Innovation Awards Articles Flow state: The evolving shape of continuous manufacturing June 17, 2025 While the pharmaceutical industry has been slow to adopt continuous manufacturing, it appears to be gaining momentum. Greg Slabodkin As a concept, continuous manufacturing — which relies on a fully integrated process that runs uninterrupted from beginning to end — has been around for many years, provi
Yu Tung Wong, Charles Bell, and Michael C. Willis Chem. Sci., 2025 DOI [link] Covalent inhibitor design is dominated by the use of electrophilic acrylamide warheads. One limitation of acrylamides is that there are limited opportunities to modify their electrophilicity, and hence reactivity, by simple structural changes. Here we show that vinyl sulfonimidamides are effective electophilic groups for reaction with both sulfur- and nitrogen-based biologically relevant nucleophiles.
Flavonoids exhibit significant potential in cancer therapy by inhibiting MMP-2 and MMP-9 activity and expression, primarily through interactions with their active sites and modulation of the MAPK signaling pathway. Our findings highlight key structure-activity relationships, paving the way for flavonoid-based inhibitors as safer alternatives to conventional treatments.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Biopharmaceutical and biotech drug developers have faced increasing challenges in recent years. In the past decade alone, the time needed to complete a clinical trial has increased by 20–30%, and the cost to bring a new drug to market has risen to an average of about $2.6 billion. Because rising costs and extended timelines have become commonplace for drug developers, implementing strategies to combat these issues is more essential than ever.
CDD Vault Update (June #2 2025): Bulk Register Sequences with Custom Monomers, Set X-axis Ranges in Plots, Filter AI Bioisostere Suggestions, Inventory Debits from ELN
The deal centers around a medicine that could “shift the treatment paradigm for cardiovascular disease,” Lilly said, but also follows a yearslong in decline in Verve’s share price amid skepticism over the need for such a therapy.
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The deal centers around a medicine that could “shift the treatment paradigm for cardiovascular disease,” Lilly said, but also follows a yearslong in decline in Verve’s share price amid skepticism over the need for such a therapy.
CDD Vault Update (June #2 2025): Bulk Register Sequences with Custom Monomers, Set X-axis Ranges in Plots, Filter AI Bioisostere Suggestions, Inventory Debits from ELN
"Uncovering Hidden Opportunities: The Secret to Unlocking Pharmaceutical Competitive Intelligence As the pharmaceutical industry continues to evolve, companies are under increasing pressure to stay ahead of the curve. But what if the key to success lies not in flashy new technologies, but in a decades-old resource that's been hiding in plain sight?
The agency cleared CSL’s hereditary angioedema drug days after “resource constraints” delayed a rival medicine. Elsewhere, Intellia revealed new data and Lilly beefed up an online service offering access to Zepbound.
TUESDAY, June 17, 2025 — Magic mushrooms might be key to quelling depression among people battling cancer.A single dose of psilocybin provided sustained reductions in depression and anxiety among cancer patients diagnosed with major depression, a.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Specialized Support to Accelerate Biotech Success Biotech innovation doesn’t slow down—and neither should your lab partner. This brief outlines how early scientific engagement, operational transparency, and integrated global lab services help reduce risk, stay on schedule, and deliver results. Whether you're navigating your first trial or scaling a growing pipeline, see how a purpose-built lab model can help you move smarter and faster. jpiatt Tue, 06/17/2025 - 10:53 Biotech innovation doesn’t s
An oldie but a goodie — a phrase used to refer to something that has fallen out of fashion but is still useful and most importantly, effective. In the research world, there is a myriad of tools this could be applied to. When it comes to altering gene expression, CRISPR technologies have gradually taken over as the preferred method for many labs. However, RNA interference (RNAi) remains steadfast in the background, a handy “oldie” as you might say.
This week, I’m rerunning some popular posts while I prepare for Friday’s live video webinar: What’s Next for Retail Pharmacy: Data, Debate, and Disruption. I’ll be joined by special guest Antonio Ciaccia, CEO of 46brooklyn Research, and President of 3 Axis Advisors. Click here to see the original post from March 2025. Three’s still company in the world of pharmacy benefit managers.
TUESDAY, June 17, 2025 — Struggling with low back pain? Slip on your walking shoes and start hoofing, a new study suggests.People who walked more than 78 minutes a day were less likely to suffer from low back pain, researchers reported.Power w.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
TUESDAY, June 17, 2025 — A diet meant to lower blood pressure also can be effective in treating type 2 diabetes after a few tweaks, a new clinical trial indicates.The DASH (Dietary Approaches to Stop Hypertension) diet effectively treated high b.
Introduction to Copilot for Power Platform Microsoft Copilot is a revolutionary AI-powered tool for Power Platform, designed to streamline the development process and enhance the intelligence of your applications. This learning path will take you through the fundamentals of Copilot and its integration with Power Apps, Power Automate, Power Virtual Agents, and AI Builder.
TUESDAY, June 17, 2025 -- The U.S. Centers for Disease Control and Prevention and the U.S. Food and Drug Administration have issued a Salmonella outbreak alert linked to pistachio cream.The agencies, in conjunction with public health officials in t.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Swearing may have helped many of us cope with the chaos of COVID, but as life settles into a new normal, it's worth considering when—and how—we use our most colorful language.
TUESDAY, June 17, 2025 — A new digital tool can flag kids who are at risk for developing childhood asthma, researchers report.The tool scans electronic health data records and calculates an asthma risk score for children, according to results p.
Getting Started with Coveo Atomic CLI This section explains how to install, configure, and deploy a Coveo Atomic project using the Coveo CLI Install the CLI To get started, install the Coveo CLI globally with npm: npm install -g @coveo/cli To ensure you’re always using the latest version, update it anytime with: npm update -g @coveo/cli Authentication Once the CLI is installed, you will need to authenticate to your coveo organization.
TUESDAY, June 17, 2025 — People caring for people with dementia might face future risk with their own brain aging due to lifestyle factors, a new study says.Nearly 3 in 5 dementia caregivers (59%) have at least one risk factor that increases their o.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
TUESDAY, June 17, 2025 — People with severe depression who receive electroshock therapy are significantly less likely to commit suicide, a new evidence review says.Electroconvulsive therapy (ECT) lowered the risk of death by suicide 34% among p.
TUESDAY, June 17, 2025 — The small, colorful bottles hawked at convenience stores, smoke shops and filling stations as cognitive supplements or energy are often called "gas station heroin." And, the U.S. Food and Drug Administration (FDA).
TUESDAY, June 17, 2025 — When Chris Williams started feeling sharp stomach pain one night in 2021, he went straight to the emergency room. The next morning, he had surgery to remove his appendix. But that wasn’t the end of his health.
TUESDAY, June 17, 2025 — The U.S. Supreme Court will hear a case next term involving a New Jersey nonprofit that runs anti-abortion pregnancy centers and is fighting a state investigation. At the center of the case is First Choice.
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