Sat.May 10, 2025 - Fri.May 16, 2025

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Boosters and Biologics: Is Space-Based Biomanufacturing Real?

LifeSciVC

By Cody Tranbarger, EIR at Atlas Venture, as part of the From The Trenches feature of LifeSciVC Its an interesting time to be thinking about space. Just a few months ago, SpaceX captivated and inspired the world by catching a reusable rocket booster with mechanical chopsticks for the first time. Meanwhile, humanitys march toward a multi-planetary future continues, with Mars on the itinerary for the 2030s (unless youre on Elon time ).

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Genome of near-extinct northern white rhino offers hope for reviving the species

Science Daily: Pharmacology News

The northern white rhinoceros is one of the rarest animals on Earth, with just two females left and no natural way for the species to reproduce. Now, scientists have mapped the entire genome of a northern white rhino. This represents a crucial step toward bringing the critically endangered species back from the edge using advanced reproductive technologies.

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Ubrogepant (Ubrelvy) Effective Against Early Migraine Symptoms

Drugs.com

WEDNESDAY, May 14, 2025 -- Migraines don’t just cause headaches. These attacks often are accompanied by symptoms like light and sound sensitivity, nausea, neck pain and dizziness. What’s more, those non-headache symptoms tend to crop.

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Synthesis Methods and Therapeutic Journey of Carprofen and Its Derivatives: A Review

Chemical Biology and Drug Design

Although it is currently only used in veterinary therapy, carprofen proves to be a molecule with a versatile therapeutic potential for human pharmacotherapy. Moreover, the molecule is a target in the drug discovery process for the development of new bioactive compounds. ABSTRACT Carprofen, a nonsteroidal anti-inflammatory drug (NSAID) derived from propanoic acid, is known for its analgesic and antipyretic properties.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Novo to work with Septerna in hunt for oral obesity drugs

BioPharma Drive: Drug Pricing

The research collaboration, under which Septerna will receive more than $200 million in upfront and near-term fees, is the latest deal Novo has struck to expand its obesity pipeline.

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UV light and CT scans helped scientists unlock hidden details in a beautifully-preserved fossil Archaeopteryx

Science Daily: Pharmacology News

Archaeopteryx is the fossil that clearly demonstrated Darwin's views. It's the oldest known fossil bird, and it helps show that all birds -- including the ones alive today -- emerged from dinosaurs. And while the first Archaeopteryx fossil was found more than 160 years ago, scientists are continuing to learn new things about this ancient animal. A set of feathers never before seen in this species help explain why it could fly when many of its non-bird dinosaur cousins could not.

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How AI and LLMs are transforming drug discovery: part 1

Drug Target Review

The integration of artificial intelligence (AI) into scientific workflows represents both tremendous opportunity and significant challenges. I recently discussed the subject with two founders at the cutting-edge of this transformation: Andr Frana of Ergodic and Eli Pollock of Ontologic. We explored the barriers scientists face when adopting AI tools , contrasting approaches to building AI systems for specialised domains, and their visions for how these technologies will reshape scientific work.

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Helpful Git Aliases To Maximize Developer Productivity

Perficient: Drug Development

Git is a powerful tool, but it can sometimes be overwhelming with the number of commands required to perform common tasks. If you’ve ever found yourself typing out long, complex Git commands and wondered if there’s a faster way to get things done, you’re not alone. One way to streamline your workflow and reduce repetitive typing is by using Git aliases.

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Astronomers take a second look at twin star systems

Science Daily: Pharmacology News

Apples-to-apples comparisons in the distant universe are hard to come by. Whether the subject is dwarf galaxies, supermassive black holes, or 'hot Jupiters,' astronomers can spend months or years searching for comparable objects and formations to study. And it is rarer still when those objects are side-by-side. But a new study offers a road map for finding 'twin' planetary systems -- showing whether binary stars that orbit each other, and that were born at the same time and place, tend to host s

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Sports, Exercise Protects Mental Health Of Growing Kids

Drugs.com

WEDNESDAY, May 14, 2025 Exercise and sports appear to help kids avoid mental health problems as they grow into young adults, a new study says.Young children who participated in sports teams and physical education classes were less likely to d.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Advancing Spatial Biology: Unlocking Insights with Nanostring Transcriptomics & Proteomics

Crown Bioscience

Spatial biology is transforming our understanding of tissue microenvironments, providing unprecedented insights into gene expression and protein interactions in situ. By preserving spatial context, researchers can gain a deeper comprehension of cellular heterogeneity and the intricate communication between cells within tissues. This field is particularly valuable in studying complex biological systems, such as tumors, the immune system, and neurological networks, where spatial relationships sign

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Celebrating Global Accessibility Awareness Day (GAAD)

Perficient: Drug Development

Today, we celebrate Global Accessibility Awareness Day (GAAD) , an annual event dedicated to raising awareness about digital accessibility and inclusion for people with disabilities. Held every third Thursday in May, GAAD encourages individuals, businesses, and organizations to reflect on the importance of creating accessible digital experiences. While GAAD highlights the needs of people with disabilities, accessibility benefits everyone not just those with disabilities.

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Cyberbullying in any form can be traumatizing for kids

Science Daily: Pharmacology News

New research shows that cyberbullying should be classified as an adverse childhood experience due to its strong link to trauma. Even subtle forms -- like exclusion from group chats -- can trigger PTSD-level distress. Nearly 90% of teens experienced some form of cyberbullying, accounting for 32% of the variation in trauma symptoms. Indirect harassment was most common, with more than half reporting hurtful comments, rumors or deliberate exclusion.

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Weight Gain, Delayed Motherhood Linked To Breast Cancer Risk

Drugs.com

WEDNESDAY, May 14, 2025 Significant weight gain paired with delayed or foregone motherhood nearly triples a young womans risk of later breast cancer, a new study says.Women were 2.7 times more likely to develop breast cancer if they:Had a more th.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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GSK to buy liver disease drug for $1.2B

BioPharma Drive: Drug Pricing

The new acquisition from Boston Pharmaceuticals adds to a wave of dealmaking undertaken by GSK to build its liver disease franchise.

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PIM for Azure Resources

Perficient: Drug Development

Privileged Identity Management Privileged Identity Management (PIM) is a service in Microsoft Entra ID that enables you to manage, control, and monitor access to important resources in your organization. These resources include those in Microsoft Entra ID, Azure, and other Microsoft Online Services such as Microsoft 365 or Microsoft Intune. This blog has been written to help those who want to set up just-in-time access for Azure resources and provide access to the subscription level only.

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Why are urban children more prone to allergies?

Science Daily: Pharmacology News

Evidence of a unique T cell may explain why urban children are more prone to allergies than rural children. Differences in the development of the gut microbiome may be an underlying cause.

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AI Can Catch Hard-To-Detect Breast Cancers In Mammograms

Drugs.com

WEDNESDAY, May 14, 2025 -- Artificial intelligence (AI) can help prevent breast cancers that develop between routine mammograms, by catching ones that trained radiologists would overlook, a new study says.Incorporating AI into mammography could.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Current Challenges With Highly Active Antiretroviral Therapy and New Hope and Horizon With CRISPR‐CAS9 Technology for HIV Treatment

Chemical Biology and Drug Design

CRISPR-CAS9 is an innovative gene editing technology to precisely remove or incorporate into the gene of interest; CRISPR-CAS9 shows promising results in HIV treatment. ABSTRACT Clustered regularly interspaced short palindromic repeats (CRISPR/Cas system) is now the predominant approach for genome editing. Compared to conventional genetic editing methods, CRISPR/Cas technology offers several advantages that were previously unavailable.

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Five questions to ask CCaaS vendors as you plan to migrate to the cloud

Perficient: Drug Development

Considering migrating your contact center operations to the cloud? Transitioning from a legacy on-premise solution to a Cloud Contact Center as a Service (CCaaS) platform offers significant advantages, including greater flexibility, scalability, improved customer experience, and potential cost savings. However, the success of this transition depends heavily on selecting the right vendor and ensuring alignment with your unique business requirements.

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Infant with rare, incurable disease is first to successfully receive personalized gene therapy treatment

Science Daily: Pharmacology News

A research team has developed and safely delivered a personalized gene editing therapy to treat an infant with a life-threatening, incurable genetic disease. The infant, who was diagnosed with the rare condition carbamoyl phosphate synthetase 1 (CPS1) deficiency shortly after birth, has responded positively to the treatment. The process, from diagnosis to treatment, took only six months and marks the first time the technology has been successfully deployed to treat a human patient.

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Celtics Star Jayson Tatum Out for Season With Torn Achilles

Drugs.com

WEDNESDAY, May 14, 2025 Boston Celtics forward Jayson Tatum will miss the rest of the season after tearing his Achilles tendon. The team announced Tuesday that Tatum had surgery to repair the injury.Tatum, 27, was hurt in the fourth quarter of M.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Bluebird extends deal deadline; Affimed files for insolvency

BioPharma Drive: Drug Pricing

Shareholders in Bluebird now have a choice of two offers from would-be acquirers Carlyle and SK Capital. Elsewhere, Cytokinetics shared more aficamten data and BridgeBio started a new kind of Attruby trial.

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The Pharmacy Benefit Management Landscape: A Music Industry Analogy

Drug Patent Watch

"The Prescription for Change: How PBM's are Ripping the Rhythm of the Pharmaceutical Industry Imagine a music industry where a single middleman controlled access to every song, dictating who could play them, when, and at what price. That's essentially the world of Pharmacy Benefit Managers (PBMs) in the pharmaceutical industry. In this exclusive article, we delve into the complex web of PBM's and their impact on the pharmacy landscape.

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New global model shows how to bring environmental pressures back to 2015 levels by 2050

Science Daily: Pharmacology News

A new study finds that with bold and coordinated policy choices -- across emissions, diets, food waste, and water and nitrogen efficiency -- humanity could, by 2050, bring global environmental pressures back to levels seen in 2015. This shift would move us much closer to a future in which people around the world can live well within the Earth's limits.

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More U.S. Teens Getting Weight-Loss Surgery

Drugs.com

WEDNESDAY, May 14, 2025 More U.S. teenagers are getting weight-loss surgery, despite the discovery of new drugs like Ozempic/Wegovy that help people drop pounds surgery-free, a new study says.Weight loss surgeries for teens increased 15% between 2.

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Human tumor response to novel natural product compounds using the POAI biobank and active machine learning

Predictive Oncology

In this white paper, Predictive Oncology (POAI) highlights a recent successful project in partnership with the University of Michigan Natural Products Discovery Core (NPDC) through the ACE program. The ACE program supports academic researchers in their early drug discovery and development initiatives by providing access to the POAI proprietary active machine learning platform and frozen patient DTC samples.

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Benjamin Cravatt

Broad Institute

Benjamin Cravatt By Rose Circeo May 14, 2025 Benjamin Cravatt, Ph.D. Ben Cravatt is professor and Norton B. Gilula Chair of Chemical Biology in the Department of Chemistry at The Scripps Research Institute. His research group is interested in developing chemical proteomic technologies that enable protein and drug discovery on a global scale and applying these methods to characterize biochemical pathways that play important roles in human physiology and disease.

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An ink that boosts coral reef settlement by 20 times

Science Daily: Pharmacology News

With coral reefs in crisis due to climate change, scientists have engineered a bio-ink that could help promote coral larvae settlement and restore these underwater ecosystems before it's too late. Researchers demonstrate that the ink could boost coral settlement by more than 20 times, which they hope could contribute to rebuilding coral reefs around the world.

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Drug Effective Against Early Migraine Symptoms

Drugs.com

WEDNESDAY, May 14, 2025 -- Migraines dont just cause headaches.These attacks often are accompanied by symptoms like light and sound sensitivity, nausea, neck pain and dizziness.Whats more, those non-headache symptoms tend to crop up before a ful.

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Computational Drug Repurposing: Approaches and Case Studies

Drug Patent Watch

"Reviving Old Medicines: How AI-Powered Repurposing is Revolutionizing the Pharmaceutical Industry The pharmaceutical industry is on the cusp of a revolution, driven by the power of computational drug repurposing. By leveraging cutting-edge AI and machine learning algorithms, researchers are breathing new life into old medicines, unlocking unprecedented potential for treating a wide range of diseases.

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HCL Commerce V9.1 – Coexistence of the Headless Next.js Ruby & Aurora Storefronts

Perficient: Drug Development

HCL Commerce v9.1 release saw a major change in features, functionality, and technology. This blog series will focus on each of these components separately. Some examples of these changes include HCL Commerce Search, which is powered by Elasticsearch, a modern storefront that uses Next.js, containerized cloud native architecture, modern business user tooling, and provides support for new integrations and companion software.