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By Cody Tranbarger, EIR at Atlas Venture, as part of the From The Trenches feature of LifeSciVC Its an interesting time to be thinking about space. Just a few months ago, SpaceX captivated and inspired the world by catching a reusable rocket booster with mechanical chopsticks for the first time. Meanwhile, humanitys march toward a multi-planetary future continues, with Mars on the itinerary for the 2030s (unless youre on Elon time ).
The northern white rhinoceros is one of the rarest animals on Earth, with just two females left and no natural way for the species to reproduce. Now, scientists have mapped the entire genome of a northern white rhino. This represents a crucial step toward bringing the critically endangered species back from the edge using advanced reproductive technologies.
WEDNESDAY, May 14, 2025 -- Migraines don’t just cause headaches. These attacks often are accompanied by symptoms like light and sound sensitivity, nausea, neck pain and dizziness. What’s more, those non-headache symptoms tend to crop.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Although it is currently only used in veterinary therapy, carprofen proves to be a molecule with a versatile therapeutic potential for human pharmacotherapy. Moreover, the molecule is a target in the drug discovery process for the development of new bioactive compounds. ABSTRACT Carprofen, a nonsteroidal anti-inflammatory drug (NSAID) derived from propanoic acid, is known for its analgesic and antipyretic properties.
Archaeopteryx is the fossil that clearly demonstrated Darwin's views. It's the oldest known fossil bird, and it helps show that all birds -- including the ones alive today -- emerged from dinosaurs. And while the first Archaeopteryx fossil was found more than 160 years ago, scientists are continuing to learn new things about this ancient animal. A set of feathers never before seen in this species help explain why it could fly when many of its non-bird dinosaur cousins could not.
THURSDAY, May 15, 2025 — The 2023 approval of the first drug shown to slow the progression of Alzheimer’s disease came with no small amount of concern from skeptics. Lecanemab (Leqembi) modestly slows Alzheimer’s by helping the.
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
THURSDAY, May 15, 2025 — The 2023 approval of the first drug shown to slow the progression of Alzheimer’s disease came with no small amount of concern from skeptics. Lecanemab (Leqembi) modestly slows Alzheimer’s by helping the.
The biotech has quickly turned a cell therapy approval into one of the more lucrative recent sales for a priority review voucher, which companies can use to fast track drug reviews.
CRISPR-CAS9 is an innovative gene editing technology to precisely remove or incorporate into the gene of interest; CRISPR-CAS9 shows promising results in HIV treatment. ABSTRACT Clustered regularly interspaced short palindromic repeats (CRISPR/Cas system) is now the predominant approach for genome editing. Compared to conventional genetic editing methods, CRISPR/Cas technology offers several advantages that were previously unavailable.
A research team has developed and safely delivered a personalized gene editing therapy to treat an infant with a life-threatening, incurable genetic disease. The infant, who was diagnosed with the rare condition carbamoyl phosphate synthetase 1 (CPS1) deficiency shortly after birth, has responded positively to the treatment. The process, from diagnosis to treatment, took only six months and marks the first time the technology has been successfully deployed to treat a human patient.
WEDNESDAY, May 14, 2025 More U.S. teenagers are getting weight-loss surgery, despite the discovery of new drugs like Ozempic/Wegovy that help people drop pounds surgery-free, a new study says.Weight loss surgeries for teens increased 15% between 2.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
A gene editing drug custom-made for a critically ill baby showed that, for some ultra-rare diseases, it’s possible to design and test a new CRISPR medicine in just a few months.
"Reviving Old Medicines: How AI-Powered Repurposing is Revolutionizing the Pharmaceutical Industry The pharmaceutical industry is on the cusp of a revolution, driven by the power of computational drug repurposing. By leveraging cutting-edge AI and machine learning algorithms, researchers are breathing new life into old medicines, unlocking unprecedented potential for treating a wide range of diseases.
New research shows that cyberbullying should be classified as an adverse childhood experience due to its strong link to trauma. Even subtle forms -- like exclusion from group chats -- can trigger PTSD-level distress. Nearly 90% of teens experienced some form of cyberbullying, accounting for 32% of the variation in trauma symptoms. Indirect harassment was most common, with more than half reporting hurtful comments, rumors or deliberate exclusion.
WEDNESDAY, May 14, 2025 Exercise and sports appear to help kids avoid mental health problems as they grow into young adults, a new study says.Young children who participated in sports teams and physical education classes were less likely to d.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
The research collaboration, under which Septerna will receive more than $200 million in upfront and near-term fees, is the latest deal Novo has struck to expand its obesity pipeline.
"The Prescription for Change: How PBM's are Ripping the Rhythm of the Pharmaceutical Industry Imagine a music industry where a single middleman controlled access to every song, dictating who could play them, when, and at what price. That's essentially the world of Pharmacy Benefit Managers (PBMs) in the pharmaceutical industry. In this exclusive article, we delve into the complex web of PBM's and their impact on the pharmacy landscape.
Until now, most research has used either generalized cell samples or organoids made from just one type of tropical fruit bat, and only from a single organ. But a breakthrough has arrived: a research team has now created the world's most comprehensive bat organoid platform. These 'mini-organs' are grown from five common bat species found across Asia and Europe and represent four different organs -- airway, lungs, kidneys, and small intestine.
WEDNESDAY, May 14, 2025 U.S. Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. is under fire after posting photos of himself and his grandchildren swimming in a long-polluted creek. The water at Rock Creek Park in Washington, D.C., i.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Shareholders in Bluebird now have a choice of two offers from would-be acquirers Carlyle and SK Capital. Elsewhere, Cytokinetics shared more aficamten data and BridgeBio started a new kind of Attruby trial.
The integration of artificial intelligence (AI) into scientific workflows represents both tremendous opportunity and significant challenges. I recently discussed the subject with two founders at the cutting-edge of this transformation: Andr Frana of Ergodic and Eli Pollock of Ontologic. We explored the barriers scientists face when adopting AI tools , contrasting approaches to building AI systems for specialised domains, and their visions for how these technologies will reshape scientific work.
Evidence of a unique T cell may explain why urban children are more prone to allergies than rural children. Differences in the development of the gut microbiome may be an underlying cause.
WEDNESDAY, May 14, 2025 -- Migraines dont just cause headaches.These attacks often are accompanied by symptoms like light and sound sensitivity, nausea, neck pain and dizziness.Whats more, those non-headache symptoms tend to crop up before a ful.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Shares of the biotech fell around 15% on news the FDA is not only taking longer to review the drug, but will assemble an outside group of advisers to evaluate it as well.
Privileged Identity Management Privileged Identity Management (PIM) is a service in Microsoft Entra ID that enables you to manage, control, and monitor access to important resources in your organization. These resources include those in Microsoft Entra ID, Azure, and other Microsoft Online Services such as Microsoft 365 or Microsoft Intune. This blog has been written to help those who want to set up just-in-time access for Azure resources and provide access to the subscription level only.
Many an orange cat-affiliated human will vouch for their cat's, let's say, specialness. But now scientists have confirmed that there is, in fact, something unique about ginger-hued domestic felines. In a new study, researchers have discovered the long-posited but elusive genetic mutation that makes orange cats orange -- and it appears to occur in no other mammal.
WEDNESDAY, May 14, 2025 The U.S. Food and Drug Administration (FDA) plans to review and possibly remove prescription fluoride supplements for children from the market.The FDA announced Tuesday that it intends to conduct the review by Oct. 31, 2.
Lars Fruergaard Jørgensen will step down after eight years helming the Danish drugmaker, shares of which have lost more than half their value over the past 12 months.
Leniolisib CAS 1354690-24-6 WeightAverage: 450.466 Monoisotopic: 450.199108558 Chemical FormulaC 21 H 25 F 3 N 6 O 2 CDZ-173-NX CDZ173 CDZ173-NX 1-[(3S)-3-({6-[6-methoxy-5-(trifluoromethyl)pyridin-3-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-4-yl}amino)pyrrolidin-1-yl]propan-1-one FDA APPROVED Joenja , 3/24/2023, To treat activated phosphoinositide 3-kinase delta syndrome Drug Trials Snapshot Leniolisib (INN [3] [4] ), sold under the brand name Joenja , is a medication used for the treatment of acti
An often-ignored type of cell in the brain plays a dynamic and surprisingly complex role in our ability to process information, according to new research.
WEDNESDAY, May 14, 2025 Significant weight gain paired with delayed or foregone motherhood nearly triples a young womans risk of later breast cancer, a new study says.Women were 2.7 times more likely to develop breast cancer if they:Had a more th.
A federal jury found Amgen liable for violating antitrust and tort laws. Elsewhere, Allogene and Kyverna trimmed staff and the FDA scheduled an advisory meeting.
HCL Commerce v9.1 release saw a major change in features, functionality, and technology. This blog series will focus on each of these components separately. Some examples of these changes include HCL Commerce Search, which is powered by Elasticsearch, a modern storefront that uses Next.js, containerized cloud native architecture, modern business user tooling, and provides support for new integrations and companion software.
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