Drugs.com
MAY 27, 2025
TUESDAY, May 27, 2025 -- The U.S. Food and Drug Administration has approved Zoryve (roflumilast) topical foam 0.3 percent for the treatment of plaque psoriasis of the scalp and body in adult and pediatric patients 12 years of age and older.Through.
Science Daily: Pharmacology News
MAY 29, 2025
Long considered a disease brought to the Americas by European colonizers, leprosy may actually have a much older history on the American continent. Scientists reveal that a recently identified second species of bacteria responsible for leprosy, Mycobacterium lepromatosis, has been infecting humans in the Americas for at least 1,000 years, several centuries before the Europeans arrived.
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BioPharma Drive: Drug Pricing
MAY 28, 2025
Weeks after shelving a TIGIT drug prospect, the biotech is seeking to sell off its assets and intellectual property in a bid to "maximize" shareholder value.
Covalent Modifiers
MAY 25, 2025
Dandan Zhu, Zijian Zheng, Huixin Huang, Xiaojuan Chen, Shuhong Zhang, Zhuchu Chen, Ting Liu, Guangyu Xu, Ying Fu, Yongheng Chen, European Journal of Medicinal Chemistry , 2025 [link] Fibroblast growth factor receptors (FGFRs) represent promising therapeutic targets in various malignancies, yet the clinical application of FGFR covalent inhibitors has been impeded by several significant challenges, including unquantifiable target engagement, undefined off-target effects, and the emergence of drug
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Drug Patent Watch
MAY 27, 2025
"Unlock Hidden Profits in Pharmaceutical R&D: A recent analysis of top-selling medications reveals that companies that closely monitor their competitors' patent portfolios are 3x more likely to achieve a higher return on investment in drug development. By staying one step ahead of the competition, can you revolutionize your approach to pharmaceutical innovation?
Science Daily: Pharmacology News
MAY 29, 2025
Anthropologists have examined the societal consequences of global glacier loss.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Covalent Modifiers
MAY 27, 2025
Birgit Wilding, Lydia Woelflingseder, Anke Baum, Krzysztof Chylinski, Gintautas Vainorius, Neil Gibson, Irene C. Waizenegger, Daniel Gerlach, Martin Augsten, Fiona Spreitzer, Yukina Shirai, Masachika Ikegami, Sylvia Tilandyov, Dirk Scharn, Mark A. Pearson, Johannes Popow, Anna C. Obenauf, Noboru Yamamoto, Shunsuke Kondo, Frans L. Opdam, Annemarie Bruining, Shinji Kohsaka, Norbert Kraut, John V.
FDA Law Blog: Biosimilars
MAY 27, 2025
By Dr. Naomi Lowy, Principal Drug Regulatory Expert FDA recently announced, CEO Forums: An FDA Listening Tour to Engage Pharma CEOs. These are scheduled to take place in several cities on both coasts in June and July (Link here). This tour to engage with pharmaceutical and biotech CEOs is unprecedented. According to the announcement, Commissioner Makary will be holding these along with Principal Deputy Commissioner Sara Brenner, M.D., M.P.H and Director of FDAs Center for Biologics Evaluation a
Science Daily: Pharmacology News
MAY 29, 2025
Spring in the Arctic brings forth a plethora of peeps and downy hatchlings as millions of birds gather to raise their young. The same was true 73 million years ago, according to a new article. The paper documents the earliest-known example of birds nesting in the polar regions.
BioPharma Drive: Drug Pricing
MAY 27, 2025
The agency recommends manufacturers update their vaccines to target the JN.1 strain. At the same time, HHS head Robert F. Kennedy Jr. is removing guidance that healthy children and pregnant women receive COVID shots.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Covalent Modifiers
MAY 28, 2025
Sara Amberntsson, Alison J Foster, Bhavik Chouhan, Stephen Wilkinson, Stephanie Harlfinger, Graham Smith, Jason G Kettle, Michael Niedbala, Stefan Kavanagh, Dominic P Williams Toxicology Research , 2025, 14, 3, tfaf054, [link] Interest in inhibiting target proteins through covalent binding mechanisms has increased in the last decade due to the potential for beneficial pharmacological properties.
Drug Target Review
MAY 26, 2025
The integration of artificial intelligence (AI) into scientific workflows represents both tremendous opportunity and significant challenges. I recently discussed the subject with two founders at the cutting edge of this transformation: Andr Frana of Ergodic and Eli Pollock of Ontologic. We considered the barriers scientists face when adopting AI tools , contrasting approaches to building AI systems for specialised domains, and their visions for how these technologies will reshape scientific work
Science Daily: Pharmacology News
MAY 29, 2025
A new study finds that if global warming exceeds the Paris Climate Agreement targets, the non-polar glacier mass will diminish significantly. However, if warming is limited to 1.5 degrees Celsius, at least 54 per cent could be preserved -- more than twice as much ice as in a 2.7 C scenario.
BioPharma Drive: Drug Pricing
MAY 27, 2025
City will receive $46 million from Biogen under the alliance. Elsewhere, Angelini Pharma licensed a rare disease therapy and the FDA refused to review a Savara lung drug.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
New Drug Approvals
MAY 26, 2025
Ervogastat CAS 2186700-33-2 Non-alcoholic Steatohepatitis (NASH) with Liver Fibrosis (FAST TRACK – U.S.) 2-[5-[(3-Ethoxy-2-pyridinyl)oxy]-3-pyridinyl]- N -[(3 S )-tetrahydro-3-furanyl]-5-pyrimidinecarboxamide ( S )-2-(5-((3-Ethoxypyridin-2-yl]oxy]pyridin-3-yl)- N -(tetrahydrofuran-3-yl)pyrimidine-5-carboxamide PF 06865571 BSOIY5AKQW 407.4 g/mol, C 21 H 21 N 5 O 4 2-[5-(3-ethoxypyridin-2-yl)oxypyridin-3-yl]- N -[(3 S )-oxolan-3-yl]pyrimidine-5-carboxamide Originator Pfizer Class Amides; Eth
Perficient: Drug Development
MAY 27, 2025
In the ever-evolving world of content management systems (CMS), there are many options to choose fromWordPress, Joomla, Drupal, and others. But for developers who love clean code, flexibility, and control, October CMS stands out as a modern, elegant solution built on the popular Laravel PHP framework. What is October CMS? October CMS is an open-source, free CMS that makes web building easier without compromising power or flexibility.
Science Daily: Pharmacology News
MAY 29, 2025
Replanting forests can help cool the planet even more than some scientists once believed, especially in the tropics. But even if every tree lost since the mid-19th century is replanted, the total effect won't cancel out human-generated warming.
BioPharma Drive: Drug Pricing
MAY 30, 2025
Ivonescimab helped cut the risk of lung tumor progression in half in a multi-country Phase 3 trial. But it hasn’t yet clearly extended survival, which will be necessary to support an FDA submission.
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thought leadership
MAY 29, 2025
On Tuesday, September 25 th , the FDA published a draft guidance containing recommendations on good review management principles and practices (GRMPs) for new drug applications (NDAs), Biologics license applications (BLAs), or efficacy supplements/supplements with clinical data. The document, entitled Good Review Management Principles and Practices for New Drug Applications and Biologics License Applications , applies to human drug applications and biosimilar biological product applications.
Perficient: Drug Development
MAY 27, 2025
In todays world, the Internet of Things (IoT) is revolutionizing industries across the globe by connecting devices, systems, and people in ways that were once unimaginable. From smart homes to advanced manufacturing, IoT is creating new opportunities for innovation, efficiency, and data-driven decision-making. At the forefront of this transformation is Microsoft Azure, a cloud computing platform that has become a powerhouse for IoT operations.
Science Daily: Pharmacology News
MAY 29, 2025
Researchers gave participants face tattoos that can track when their brain is working too hard. The study introduces a non-permanent wireless forehead e-tattoo that decodes brainwaves to measure mental strain without bulky headgear. This technology may help track the mental workload of workers like air traffic controllers and truck drivers, whose lapses in focus can have serious consequences.
BioPharma Drive: Drug Pricing
MAY 29, 2025
A therapy at the center of their $22 billion alliance failed to extend survival in a type of lung tumor, leading the companies to abandon a U.S. submission.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drug Patent Watch
MAY 26, 2025
"The Secret Sauce Behind Switzerland's Thriving Pharma Scene: It's Not Just About Chocolate and Mountains As the global pharma landscape continues to evolve, one country stands out for its remarkable success: Switzerland. With a market share of over 25% of the global pharmaceutical industry, the Swiss pharma sector is a powerhouse to be reckoned with.
Perficient: Drug Development
MAY 28, 2025
The digital tide of Generative AI is sweeping across the globe, reshaping industries, revolutionizing creativity, and promising a future brimming with unimaginable possibilities. From crafting compelling prose to composing intricate melodies, from designing breathtaking visuals to simulating complex realities, Generative AI has moved from the realm of science fiction into our everyday lives with astonishing speed.
Science Daily: Pharmacology News
MAY 28, 2025
In a major leap forward for genetic and biomedical research, scientists have developed a powerful new artificial intelligence tool that can predict the 3D shape of chromosomes inside individual cells -- helping researchers gain a new view of how our genes work.
BioPharma Drive: Drug Pricing
MAY 27, 2025
The startup is the latest beneficiary of investors’ appetite for protein-degrading technology, which offers a way to reach drug targets other technologies can’t.
thought leadership
MAY 29, 2025
On Wednesday, August 1 st , FDA released a notice with updated prescription drug user fee rates for fiscal year 2019.
Perficient: Drug Development
MAY 28, 2025
Imagine you are retrieving an API key/Bearer token from an external system to make a new callout to another external system. But there is one issue: you cannot determine when the new callout will take place, so you need to store the token value somewhere in your org for later use. Probably you will be thinking of storing it in your custom object or custom metadata.
Science Daily: Pharmacology News
MAY 29, 2025
A new study reveals that the aerobic nitrogen cycle in the ocean may have occurred about 100 million years before oxygen began to significantly accumulate in the atmosphere, based on nitrogen isotope analysis from ancient South African rock cores. These findings not only refine the timeline of Earth's oxygenation but also highlight a critical evolutionary shift, where life began adapting to oxygen-rich conditions -- paving the way for the emergence of complex, multicellular organisms like humans
BioPharma Drive: Drug Pricing
MAY 27, 2025
The demand for fill/finish services has never been greater, how are CDMOs responding?
Fierce BioTech
MAY 27, 2025
Is it time to go beyond classic design in oncology trials? jgrcic Tue, 05/27/2025 - 11:55 Tue, 05/27/2025 - 11:55 Resource Type Whitepaper Promotion Start Tue, 05/27/2025 - 12:06 Use of healthy volunteers in first-in-human trials with oncology small molecules. Can an alternative approach expedite clinical development of small molecule oncology drugs and benefit patients?
Drug Patent Watch
MAY 28, 2025
"Generic Medications: The Unseen Struggle for Quality Control As the pharmaceutical industry grapples with the complexities of generic drug production, a hidden crisis is unfolding. Despite their lower price points, generic medications often fall short of their branded counterparts in terms of quality and consistency. But what if I told you there's a way to bridge this gap?
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