Drugs.com
JANUARY 2, 2025
THURSDAY, Jan. 2, 2024 -- Weight loss tops many folks list of New Years resolutions, and lots of people are turning to cutting-edge weight-loss drugs like Ozempic to help them drop excess pounds.These drugs, called glucagon-like peptide-1 receptor.
Science Daily: Pharmacology News
JANUARY 2, 2025
Researchers have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this protein was able to restore the heart by activating dormant repair genes without causing side effects, such as heart enlargement. This study marks an important step toward regenerative therapies to prevent heart failure.
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Covalent Modifiers
DECEMBER 28, 2024
Ai-Lin Chen, Zih-Jheng Lin, Hsiao-Yu Chang, and Tsung-Shing Andrew Wang Journal of the American Chemical Society , 2025 [link] Reactive carbonyl species (RCS) are important biomarkers of oxidative stress-related diseases because of their highly reactive electrophilic nature. Despite their potential as triggers for prodrug activation, selective labeling approaches for RCS remain limited.
BioPharma Drive: Drug Pricing
JANUARY 2, 2025
Expected readouts in diabetes, cancer and depression headline a series of study results that could help the biotechnology sector regain its footing after a shaky year.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Drugs.com
DECEMBER 30, 2024
MONDAY, Dec. 30, 2024 -- Norovirus, a highly contagious stomach bug, is surging across the United States this winter, according to the latest data from the U.S. Centers for Disease Control and Prevention (CDC).The data shows 91 outbreaks of.
Science Daily: Pharmacology News
JANUARY 1, 2025
Researchers have come up with a new way to identify more infectious variants of viruses or bacteria that start spreading in humans -- including those causing flu, COVID, whooping cough and tuberculosis.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Chemical Biology and Drug Design
DECEMBER 30, 2024
Compound 8w suppressed BaF3 cells harboring CCDC6-RET V804M mutations with IC 50 values of 0.715M and dose-dependently suppressed the activation of RET and downstream signals. Another compound 8s suppressed BaF3 cells harboring CCDC6-RET G810C mutation with an IC 50 value of 2.91M. Therefore, 8w and 8s might be promising lead compounds. ABSTRACT RET (Rearranged during transfection) kinase is a validated target for non-small cell lung cancer (NSCLC).
Drugs.com
JANUARY 3, 2025
FRIDAY, Jan. 3, 2025 -- If you've picked up a bag of Marketside Broccoli Florets from Walmart recently, check your fridge or freezer. The company has issued a recall of the 12-ounce bags in 20 states after testing uncovered listeria bacteria in one.
Science Daily: Pharmacology News
JANUARY 2, 2025
A research team has developed a method for extracting gold from electronics waste, then using the recovered precious metal as a catalyst for converting carbon dioxide (CO2), a greenhouse gas, to organic materials.
BioPharma Drive: Drug Pricing
JANUARY 2, 2025
The well-funded biotech lost most of its value after its drug flunked a late-stage trial. One analyst described the results as a “worst-case scenario for the program.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Molecular Design
DECEMBER 31, 2024
My pulse will be quickenin' With each drop of strychnine We feed to a pigeon It just takes a smidgin To poison a pigeon in the park Tom Lehrer, Poisoning Pigeons in the Park | video ** Ill be reviewing the H2024 study (Occurrence of Natural Selection in Successful Small Molecule Drug Discovery) in this post. Derek has already posted on the H2024 study which been included in the BL2024 Virtual Special Issue on natural products (NPs) in medicinal chemistry.
Drugs.com
JANUARY 2, 2025
THURSDAY, Jan. 2, 2024 -- Not sure what’s causing your child’s asthma? A new quick-and-easy nasal swab test for kids can diagnose the specific immune system drivers behind their asthma, potentially opening the door to better treatments.
Science Daily: Pharmacology News
JANUARY 3, 2025
Scientists recently discovered that the giant 'conveyer belt' currents that push star-forged material out of our galaxy and pull it back in can also transport carbon atoms. That means that a good deal of the carbon here on Earth, including the carbon in our bodies, likely left the galaxy at some point!
BioPharma Drive: Drug Pricing
JANUARY 2, 2025
The agency’s main drug review office cleared 50 novel medicines last year, short of 2018’s record total but on the higher end of recent annual tallies.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Collaborative Drug
DECEMBER 30, 2024
2024 was a special year as we celebrated two decades of CDD Vault.
Drugs.com
JANUARY 2, 2025
THURSDAY, Jan. 2, 2025 -- Considering a New Year’s resolution to quit smoking? New research might provide all the motivation you need: Each cigarette could shorten your life by up to 22 minutes, researchers say. The findings, published Dec.
Science Daily: Pharmacology News
JANUARY 3, 2025
Interactions with friends and family may keep us healthy because they boost our immune system and reduce our risk of diseases such as heart disease, stroke and type 2 diabetes, new research suggests. Researchers drew this conclusion after studying proteins from blood samples taken from over 42,000 adults recruited to the UK Biobank.
BioPharma Drive: Drug Pricing
JANUARY 2, 2025
Sangamo shares fell on Pfizer’s decision to hand back rights to a hemophilia gene therapy. Elsewhere, Novartis got long-awaited data and BioNTech settled with the NIH.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drug Patent Watch
DECEMBER 30, 2024
The regulatory environment in Japan for generic drug development is complex and has undergone significant changes in recent years. This article aims to provide a comprehensive overview of the key aspects of the regulatory framework, highlighting the requirements and challenges faced by pharmaceutical companies seeking to introduce generic drugs into the Japanese market.
Drugs.com
JANUARY 2, 2025
THURSDAY, Jan. 2, 2025 -- A Canadian teen's severe bird flu infection has highlighted growing concerns about the H5N1 virus, commonly known as bird flu, which has seen a steady rise in human cases across the U.S. According to a news release, the.
Science Daily: Pharmacology News
JANUARY 3, 2025
Bioengineers have developed a new construction kit for building custom sense-and-respond circuits in human cells. The research could revolutionize therapies for complex conditions like autoimmune disease and cancer.
Perficient: Drug Development
DECEMBER 30, 2024
This blog provides a detailed explanation of the technical approach for implementing Continuous Deployment (CD) processes within Azure DevOps. It focuses on automating the deployment of solutions to SharePoint environments. This approach not only speeds up the release cycle but also enhances reliability, minimizes errors, and ensures that updates are deployed quickly and effectively.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Chemical Biology and Drug Design
DECEMBER 29, 2024
Cover Image molekuul_be/Shutterstock.
Drugs.com
DECEMBER 28, 2024
SATURDAY, Dec. 27, 2024 -- Schoolkids will be better able to save the life of a cardiac arrest victim, thanks to a new law signed this week by President Joe Biden.The Cardiomyopathy Health Education, Awareness, Research and Training in Schools.
Science Daily: Pharmacology News
JANUARY 1, 2025
Waves of human migration across Europe during the first millennium AD have been revealed using a more precise method of analysing ancestry with ancient DNA, in research led by the Francis Crick Institute.
Perficient: Drug Development
DECEMBER 30, 2024
Generative AI is rapidly transforming the world around us. From creating stunning artwork to composing music and even writing code, its capabilities are vast and expanding at an unprecedented rate. This blog post will serve as a comprehensive introduction to Generative AI, guiding you through its foundational concepts and exploring the groundbreaking features of ChatGPT.
National Institute on Drug Abuse: Nora's Blog
JANUARY 3, 2025
A new roadmap for cannabis and cannabis policy research mfleming Fri, 01/03/2025 - 11:38 Nora's Blog January 14, 2025 Image Getty Images/ Fiordaliso The greatly increased availability of cannabis over the last two decades has outpaced our understanding of the public-health impacts of the drug. It is now available for medical purposes in most states, and adults may now purchase it for recreational use in nearly half the states.
Drugs.com
JANUARY 3, 2025
FRIDAY, Jan. 3, 2025 -- Wondering which popular diet will help you shed extra weight in a healthy way this year?The Mediterranean diet tops the best diet categories in the U.S. News & World Report 2025 edition.According to the report, the.
Science Daily: Pharmacology News
JANUARY 2, 2025
Viral infections may play a role in Alzheimer's disease.
Perficient: Drug Development
DECEMBER 31, 2024
Artificial Intelligence (AI) is revolutionizing B2B e-commerce, enabling capabilities such as personalized product recommendations, dynamic pricing, and predictive analytics. However, the effectiveness of these AI-driven solutions depends heavily on the quality of the underlying data. Despite AI’s potential, poor data governance remains a significant challenge in the industry.
Fierce BioTech
JANUARY 3, 2025
Innovation in container closer systems and aseptic processing for ATMPs dwunderlin Fri, 01/03/2025 - 14:26 Wed, 02/12/2025 - 10:00 Resource Type Webinar Jim Thompson Julian Petersen Duration 60 Minutes The pharmaceutical landscape is shifting from blockbuster drugs to personalized treatments, driving the need for innovative container closure systems.
Drugs.com
JANUARY 3, 2025
FRIDAY, Jan. 3, 2025 -- The lungs are a tempting place for cancer cells -- so much so that more than half of people with advanced cancer elsewhere in their bodies wind up with lung tumors.Researchers now think they know why.Elevated levels of an.
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