Engineering Immune Response Molecular Biology 
Codon
JUNE 5, 2025
The core of the CRISPR immune response is a guide RNA (gRNA) that binds to a CRISPR-associated (Cas) protein. Researchers have engineered more specific enzymes — possessing drastically reduced off-target effects — by altering either the structure of the Cas9 protein itself or its gRNA. Join Asimov Press.
Drug Target Review
FEBRUARY 28, 2024
These include engineering the cells to express cytokines that promote their maturation and/or differentiation, and engineering drug-resistant γδ T cells that can be combined with chemotherapies, which stress cancer cells but would otherwise also deplete the T-cell population. and MBA students with real-world consulting experiences.
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The Pharma Data
JANUARY 4, 2021
Chimeric PD-1 T-cells also release cytokines to further initiate immune responses to eradicate the tumor cells. is a preclinical stage biopharmaceutical company which is focused on discovering, developing, and commercializing novel immune-oncology applications through its robust product pipeline. About Longwood University.
Broad Institute
AUGUST 7, 2023
MIT biology PhD student Bingxu Liu and Rebecca Carlson PhD ’23, a recent graduate of the Medical Engineering and Medical Physics program through the Harvard-MIT Division of Health Sciences and Technology, are the lead authors of the paper, which appears in Science. Paper Cited Liu B, Carlson R, et al. Human STING is a proton channel.
Codon
APRIL 2, 2024
A gene encoding green fluorescent protein was placed alongside one of the three promoters, and as the engineered cells cycled from one gene to the next, they blinked between green—dark—green—dark. These papers became the standard-bearers for a new scientific field: synthetic biology. Another one is immunogenicity.
Codon
FEBRUARY 13, 2024
Such contaminants could have the same toxic effects as the bacterial infection, or provoke a severe immune response in the patient, and therefore the phage mixtures must go through extensive purification and testing procedures. The resulting data are fed into an analytical engine that runs millions of simulations. aeruginosa, S.
Codon
JULY 27, 2023
.” Wellcome Collection , London I wrapped up my series on “30 Days of Great Biology Papers.” ” This was a series of tweets in which I told brief stories behind seminal papers, mostly in molecular biology and biophysics. a lower risk of immune responses. You can read all of them here.
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