Remove Immune Response Remove Molecular Biology Remove RNA
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A Visual Guide to Genome Editors

Codon

The core of the CRISPR immune response is a guide RNA (gRNA) that binds to a CRISPR-associated (Cas) protein. In wild microbes, Cas9 cuts DNA using two separate RNA molecules, called the CRISPR RNA (crRNA) and trans-activating RNA (tracrRNA). Visit our website to get a copy. Join Asimov Press.

DNA 81
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Scientists discover network of cells and genes involved in Crohn’s disease complication

Broad Institute

Isselbacher Professor of Medicine at Harvard Medical School, and director of the Center for Computational and Integrative Biology and core member in the Department of Molecular Biology at Massachusetts General Hospital. Lingjia Kong, a research scientist in the Xavier lab, is the first author on the study.

Disease 111
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Unlocking Undruggable Targets: Shifting Paradigms in Modern Drug Discovery

DrugBank

But as molecular biology has advanced, so too has our approach to finding new drugs. Another promising avenue is the use of technologies like RNA interference and gene editing, which allow scientists to turn off the production of certain proteins altogether. This method was more about serendipity than science.

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Phages could help to tackle antimicrobial resistance

Drug Target Review

Phage have been of interest to scientists as tools to understand fundamental molecular biology, as vectors of horizontal gene transfer and drivers of bacterial evolution, as sources of diagnostic and genetic tools, and as novel therapeutic agents. In bacteria , cGAS-like cyclases are central parts of the CBASS immune response.

RNA 59
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A Look Back

Dark Matter Blog

The only subject in school that held my interest was biology. As soon as I learned about DNA and RNA, I wanted to be a molecular biologist. I wanted to use molecular biology to create drugs. Last stops at RNA My last roles in biotech were where my original passion began: DNA and RNA.

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A Molecular Biologist’s Advice For Life

LifeSciVC

The central dogma of molecular biology is that information generally (with few exceptions) flows from DNA to RNA to Protein. Build your social immunity. The adaptive immune response identifies and responds to highly specific antigens associated with infections and cancer. Remember life’s Central Dogma.

Science 92
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Scientists find a region of the mouse gut tightly regulated by the immune system

Broad Institute

Isselbacher Professor of Medicine at Harvard Medical School, director of the Center for Computational and Integrative Biology and member of the Department of Molecular Biology at MGH, and co-director of the Center for Microbiome Informatics and Therapeutics at MIT.