Drug Target Review

JUNE 6, 2023

Delivery of therapy is being evaluated through injections of DNA and RNA encoding IL-12, viral vectors, and other exploratory platforms designed to bring IL-12 in close proximity to the tumour and avoid excessive IL-12 in systemic circulation. American Association for Cancer Research; 2006 [cited 2023 Jun 6].

Engineering 98

Engineering Immune Response Biochemical Pharmacology Clinical Trials 98

New Drug Approvals

JANUARY 9, 2024

CDK7 also plays a role in transcription and possibly in DNA repair. The trimeric Cak complex CDK7/CyclinH/MATl is also a component of TFIIH, the general transcription/DNA repair factor IIH (Morgan, DO., As a TFIIH subunit, CDK7 phosphorylates the CTD (Carboxy-Terminal-Domain) of the largest subunit of RNA polymerase II (pol II).

Production 62

Production DNA RNA Regulations 62

Drug Target Review

JANUARY 24, 2024

Scientists from Northwestern Medicine have demonstrated that RNA interference could have a crucial role in the onset and development of Alzheimer’s disease (AD). sRNAs Cellular functions rely on numerous protein-coding and noncoding RNAs and the RNA-binding proteins associated with them, which form ribonucleoprotein complexes (RNPs).

RNA 64

RNA Disease DNA Engineering 64

Codon

AUGUST 27, 2024

Allison Berke makes the case for real-time DNA sequencing and AI tools to detect pathogens before they spread widely. Reading DNA The first step in detecting a novel pathogen is recognizing it as an anomaly amidst a noisy background of other material. After copying the DNA to form a big pool, each piece is sequenced.

DNA 109

DNA Laboratories Hospitals Virus 109

PLOS: DNA Science

MARCH 30, 2023

GISAID began in 2006 in response to bird flu, becoming a global clearinghouse for data and maps galore on epidemic and pandemic viruses. Comparing genome sequences is important because they provide a 4-letter language in the bases A, C, G, and T (for DNA) or A, C, G, and U (for RNA).

DNA 52

DNA Hospitals Laboratories Virus 52

Codon

AUGUST 28, 2024

Tessa Alexanian and Max Langenkamp build computational DNA screening tools for a living. But today, rapid advances in DNA synthesis have made it possible for would-be bioterrorists to make pathogens, rather than buy them. Credit: Alamy In a 2006 report , the U.S. This article concludes our mini-issue. Thanks for reading!

DNA 103

DNA Bioinformatics Virus Government 103

Codon

MAY 15, 2025

In 2006, researchers at the University of Alberta tried to replicate a 1993 mouse study. Random mutations in DNA bring about this genetic variation, and mating between unrelated individuals mixes the mutations amongst the population. percent of the mouse’s DNA. Credit: Wahlsten D. Genetics are partly to blame.

DNA 75

DNA Laboratories RNA Regulations 75