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A Visual Guide to Genome Editors

Codon

For example, one can fuse a deactivated Cas9 protein to so-called “transcriptional regulators” to either activate or repress genes without directly editing the genome at all. It was first characterized in 2016 by Feng Zhang’s lab. Fanzors have been identified in everything from clams and algae to butterflies.)

DNA 83
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SRP-001: redefining pain treatment with a safer, non-opioid analgesic

Drug Target Review

SRP-001 targets the central nervous system (CNS) by producing N-arachidonoylaminophenol (AM404) in the midbrain’s periaqueductal grey (PAG) region, crucial for pain sensation and regulation. was founded in 2016 to develop safer, non-opioid therapies for acute and chronic pain. South Rampart Pharma, Inc.

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Alzheimer’s disease: driving advancements with precision medicine

Drug Target Review

2016, August 2). Progress in molecular biology and translational science. Α-synuclein in the pathophysiology of alzheimer’s disease – molecular neurodegeneration. FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer’s disease.

Disease 59
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Scaling Phage Therapy

Codon

Regulators traditionally want to see a single, stable, well-characterized drug before giving the green light for it to be tested in a clinical trial, not dozens of different viruses; let alone ones that are best found in unappealing places like sewage , hospital waste, or bird poop.

Therapies 138
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The Promise of Gas Vesicles

Codon

Even after a half-century of molecular biology research, scientists didn’t know until recently how gas vesicles physically trap gas while occluding water. For more than a century, scientists thought of gas vesicles as little more than a natural curiosity and, later, as a way for microbes to regulate buoyancy.

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Codon Digest: Hackathon Prize Winners

Codon

In 2016, Belmonte “reported that sick mice lived 30% longer than expected after receiving a cocktail of special reprogramming proteins,” according to the article in MIT Technology Review. Future Nobel Laureate, Paul Berg, narrated the video, which quickly became a cult classic moment in molecular biology history.

DNA 52
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Codon Digest: Hackathon Prize Winners

Codon

In 2016, Belmonte “reported that sick mice lived 30% longer than expected after receiving a cocktail of special reprogramming proteins,” according to the article in MIT Technology Review. Future Nobel Laureate, Paul Berg, narrated the video, which quickly became a cult classic moment in molecular biology history.

DNA 52