2025 - Drug Discovery Digest

How AI will reshape pharma by 2025

Drug Target Review

DECEMBER 20, 2024

Looking ahead, 2025 could represent a major turning point for the pharmaceutical sector. In 2025, I think well see breakthroughs that allow us to make significant advances in rare diseases, where the data is small. While current breakthroughs are impressive, Smith anticipates even greater advancements by 2025.

Clinical Trials

Clinical Trials Trials Pharmaceuticals Drug Development

Ubrogepant (Ubrelvy) Effective Against Early Migraine Symptoms

Drugs.com

MAY 14, 2025

WEDNESDAY, May 14, 2025 -- Migraines don’t just cause headaches. These attacks often are accompanied by symptoms like light and sound sensitivity, nausea, neck pain and dizziness. What’s more, those non-headache symptoms tend to crop.

Fluoride Ban Could Create Cavities For 1 Of Every 3 U.S. Kids

Drugs.com

JUNE 2, 2025

MONDAY, June 2, 2025 Removing fluoride from the U.S. water supply could result in more than 25 million more decayed teeth in children and teenagers within five years, a new study warns.Thats the equivalent of a decayed tooth for 1 of every 3 kid.

FDA Limits COVID-19 Boosters to Seniors, Other High-Risk Groups

Drugs.com

MAY 21, 2025

WEDNESDAY May 21, 2025 The U.S. Food and Drug Administration (FDA) has decided that only seniors and people at high risk should get the latest COVID-19 booster shots this fall.The new framework, announced Tuesday, says adults 65 and older, and p.

FDA

FDA Drugs

Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

📆 May 14th, 2025 at 9:30 AM PDT, 12:30 PM EDT, 5:30 PM BST Navigating the AI Landscape 🤖 Explore the opportunities and challenges with integrating AI in healthcare and disease prevention. Register today to save your seat!

Clinical Trials

GLP-1 Drugs Appear To Lower Cancer Risk

Drugs.com

MAY 19, 2025

MONDAY, May 19, 2025 Cutting-edge GLP-1 weight-loss drugs appear to help lower cancer risk even beyond the benefits from dropping excess pounds, a new study says.First-generation GLP-1 drugs like liraglutide (Saxenda) and exenatide (Byetta) were a.

Drugs

CDD Vault Update (May 2025): New PDB Viewer, AI Similarity Searches, Registered IDs in AI Results, Inventory Unit Conversion, Visualize Batch Data, Nucleotide to Amino Acid Sequence Translation

Collaborative Drug

MAY 19, 2025

CDD Vault Update (May 2025): New PDB Viewer, AI Similarity Searches, Registered IDs in AI Results, Inventory Unit Conversion, Visualize Batch Data, Nucleotide to Amino Acid Sequence Translation

CDD Vault Update (April 2025 #3): AI+ Folding and Docking

Collaborative Drug

APRIL 25, 2025

CDD Update March #2 2025 Full Atom Layout of Macromolecules New Dataset for AI Similarity Searching Import Inventory Locations by Unique Box Names:

Alzheimer’s Drug, Leqembi, Can Be Safely Administered In Memory Clinics, Study Says

Drugs.com

MAY 15, 2025

THURSDAY, May 15, 2025 — The 2023 approval of the first drug shown to slow the progression of Alzheimer’s disease came with no small amount of concern from skeptics. Lecanemab (Leqembi) modestly slows Alzheimer’s by helping the.

Drugs

Drugs Disease

Moderna's New Lower-Dose COVID-19 Vaccine, mNexspike, Approved by FDA

Drugs.com

JUNE 3, 2025

TUESDAY, June 3, 2025 -- The U.S. Food and Drug Administration has approved a new lower-dose vaccine for active immunization against COVID-19 caused by severe acute respiratory syndrome coronavirus 2. The new vaccine (mNexspike [COVID-19 Vaccine.

Vaccine

Vaccine FDA Drugs

5 questions facing emerging biotech in 2025

BioPharma Drive: Drug Pricing

JANUARY 14, 2025

Young drugmakers confront several harsh realities this year, among them a contracting sector and competition from China.

Too Much Cinnamon May Interfere With Some Medications, Study Shows

Drugs.com

MAY 5, 2025

MONDAY, May 5, 2025 Consuming too much cinnamon might affect how your body absorbs some medications, new research shows.The study published in the June issue of the journal Food Chemistry: Molecular Sciences looked at how cinnamon and its key.

Science

Science Research

More U.S. Teens Getting Weight-Loss Surgery

Drugs.com

MAY 14, 2025

WEDNESDAY, May 14, 2025 More U.S. teenagers are getting weight-loss surgery, despite the discovery of new drugs like Ozempic/Wegovy that help people drop pounds surgery-free, a new study says.Weight loss surgeries for teens increased 15% between 2.

Drugs

Florida-Grown Cucumbers Behind Salmonella Outbreak, CDC Warns

Drugs.com

MAY 21, 2025

WEDNESDAY, May 21, 2025 Health officials are investigating a salmonella outbreak tied to cucumbers grown in Florida. At least 26 people across 15 states have gotten sick, and nine people have been hospitalized, the U.S. Food and Drug A.

Hospitals

Hospitals Drugs

Sports, Exercise Protects Mental Health Of Growing Kids

Drugs.com

MAY 14, 2025

WEDNESDAY, May 14, 2025 Exercise and sports appear to help kids avoid mental health problems as they grow into young adults, a new study says.Young children who participated in sports teams and physical education classes were less likely to d.

Pepto Bismol May Not Prevent Traveler’s Diarrhea, New Study Finds

Drugs.com

JUNE 4, 2025

WEDNESDAY, June 4, 2025 Pepto Bismol is a go-to stomach remedy, but a new study suggests it might not help prevent diarrhea during international travel.The study, led by the U.S. Centers for Disease Control and Prevention (CDC), found that people.

International

International Disease

Coffee Could Be Key To Aging Gracefully

Drugs.com

JUNE 4, 2025

WEDNESDAY, June 4, 2025 A morning cup of coffee might do more than momentarily boost your energy and spirits.Full-test java also appears to help women age more gracefully, a new study says.Middle-aged women who regularly drank caffeinated coffee w.

Drug Effective Against Early Migraine Symptoms

Drugs.com

MAY 14, 2025

WEDNESDAY, May 14, 2025 -- Migraines dont just cause headaches.These attacks often are accompanied by symptoms like light and sound sensitivity, nausea, neck pain and dizziness.Whats more, those non-headache symptoms tend to crop up before a ful.

Drugs

RFK Jr. Criticized for Swimming With Grandkids in Bacteria-Filled Creek

Drugs.com

MAY 14, 2025

WEDNESDAY, May 14, 2025 U.S. Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. is under fire after posting photos of himself and his grandchildren swimming in a long-polluted creek. The water at Rock Creek Park in Washington, D.C.,

CDD Vault Update (March #2 2025): Macromolecule Atomistic Rendering, AI Datasets, Import Inventory Locations, Larger Inventory Boxes, Dark Mode

Collaborative Drug

MARCH 19, 2025

CDD Update March #2 2025 Full Atom Layout of Macromolecules New Dataset for AI Similarity Searching Import Inventory Locations by Unique Box Names:

HHS, NIH Unveil Vaccine Initiative to Protect Against Future Pandemics

Drugs.com

MAY 2, 2025

FRIDAY, May 2, 2025 -- The U.S. Department of Health and Human Services and the National Institutes of Health announced a new initiative called "Generation Gold Standard" to develop next-generation, universal vaccines using a beta-propiolactone.

Vaccine

FDA Launches Postmarket Chemical Review Program to Ensure Food Safety

Drugs.com

MAY 19, 2025

MONDAY, May 19, 2025 -- Last week, the U.S. Food and Drug Administration announced a move to improve transparency and strengthen the safety of chemicals used in the nation's food supply.The agency is implementing an enhanced review process for food.

FDA

FDA Drugs

Blood, Urine Tests Can Identify Level Of Ultra-Processed Food In Diet

Drugs.com

MAY 21, 2025

WEDNESDAY, May 21, 2025 Worried youre scarfing down too many ultra-processed foods?Blood Blood and urine tests might be able to reveal how much of your diet is made up of industrially produced foods, a new study says.Chemicals produced as the body con.

Troubled Kids Wait a Half-Day — Or More — In ER To Get Mental Health Care

Drugs.com

JUNE 4, 2025

WEDNESDAY, June 4, 2025 Troubled children and teenagers are languishing hours in chaotic hospital emergency rooms, waiting for a psychiatric bed to open, a new study says.About 1 in 3 kids who go to an emergency room (ER) amid a mental health c.

Hospitals

FDA to Review and Possibly Ban Fluoride Supplements for Kids

Drugs.com

MAY 14, 2025

WEDNESDAY, May 14, 2025 The U.S. Food and Drug Administration (FDA) plans to review and possibly remove prescription fluoride supplements for children from the market.The FDA announced Tuesday that it intends to conduct the review by Oct.

FDA

FDA Drugs

Feeling Work Stress? Your Dog Might Be Feeling It Too

Drugs.com

MAY 31, 2025

SATURDAY, May 31, 2025 Stress from work doesnt always stay at the office and it may be affecting more than just your mood. A new study finds that your dog may be picking up on it, too, especially if you have a hard time letting go of work worri.

CDD Vault Update (April 2025 #2): Pharmacokinetic (PK) and Michaelis-Menten Kinetics (Km/Kd) Curve Fit Equations, Donut Charts, TIFF Image Previews, and Parallel Reactions

Collaborative Drug

APRIL 18, 2025

CDD Update March #2 2025 Full Atom Layout of Macromolecules New Dataset for AI Similarity Searching Import Inventory Locations by Unique Box Names:

Pharmacokinetics

Drug Discovery Informatics for Big Pharma: Key Webinar Insights

Collaborative Drug

MARCH 21, 2025

Our recent Q1 2025 scientific webinar brought together industry veterans Dr. Chris Waller and Dr. Dimitris Agrafiotis to discuss the current state and future directions of drug discovery informatics in large pharmaceutical organizations led by CDD's Founder and CEO, Dr.

Drugs

Drugs Pharmaceuticals

Former President Joe Biden Diagnosed With Aggressive Prostate Cancer

Drugs.com

MAY 19, 2025

MONDAY, May 19, 2025 Former President Joe Biden has been diagnosed with advanced prostate cancer that has spread to his bones, his office announced Sunday.Doctors found the cancer after Biden reported urinary symptoms. Testing showed a small n.

Man Bitten by Snakes 200 Times May Help Create New Antivenom

Drugs.com

MAY 5, 2025

MONDAY, May 5, 2025 Tim Friede has survived hundreds of snakebites on purpose. For nearly two decades, he let some of the worlds most dangerous snakes sink their fangs into his arms, all for science.Now, his bold experiment could potentially he.

Nebraska First State to Ban Soda, Energy Drinks From SNAP Program

Drugs.com

MAY 21, 2025

WEDNESDAY, May 21, 2025 Nebraska is the first state to get federal approval to ban the purchase of soda and energy drinks under the Supplemental Nutrition Assistance Program (SNAP), also known as food stamps.The change, announced Monday by U.S.

New Drug Could Quell Uncontrolled High Blood Pressure

Drugs.com

MAY 5, 2025

MONDAY, May 5, 2025 An experimental drug might help people with uncontrolled high blood pressure, according to early clinical trial results.People taking lorundrostat experienced twice the decline in their systolic blood pressure than people t.

Clinical Trials

Clinical Trials Drugs Trials

Fido Might Protect Your Baby Against Eczema

Drugs.com

JUNE 5, 2025

THURSDAY, June 5, 2025 Having a family dog might decrease a babys risk of developing eczema later in childhood, a new evidence review says.Specifically, exposure to canines appears to influence a childs genetic risk of eczema, by blunting skin i.

Doctors Perform First-Ever Human Bladder Transplant in U.S.

Drugs.com

MAY 19, 2025

MONDAY, May 19, 2025 Doctors in Southern California have performed the first human bladder transplant, offering new hope to people with serious bladder problems.The surgery was done earlier this month by two doctors from the University of C.

Doctors

White House Report Blames Toxins, Food and Screens for Poor Health

Drugs.com

MAY 23, 2025

FRIDAY, May 23, 2025 A new White House report says todays children are the sickest generation in U.S. history when it comes to chronic disease, and it puts the blame on environmental toxins, poor nutrition and too much screen time.Called the "MA.

Disease

Couch Potatoes Have Greater Risk Of Brain Decline, Even If They Exercise

Drugs.com

MAY 19, 2025

MONDAY, May 19, 2025 Couch potatoes are more likely to develop Alzheimers disease, even if they set aside time to work out each day, a new study says.People who spent more time sitting around were more likely to experience cognitive decline and b.

Disease

Chemoselective Stabilized Triphenylphosphonium Probes for Capturing Reactive Carbonyl Species and Regenerating Covalent Inhibitors with Acrylamide Warheads in Cellulo

Covalent Modifiers

DECEMBER 28, 2024

Ai-Lin Chen, Zih-Jheng Lin, Hsiao-Yu Chang, and Tsung-Shing Andrew Wang Journal of the American Chemical Society , 2025 [link] Reactive carbonyl species (RCS) are important biomarkers of oxidative stress-related diseases because of their highly reactive electrophilic nature.

Disease

Disease Production

9 In 10 U.S. Teens Have Been Cyberbullied

Drugs.com

MAY 21, 2025

WEDNESDAY, May 21, 2025 -- Cyberbullying is widespread among U.S. teens and is linked to post-traumatic stress symptoms in middle- and high-school students, a new study says.Nearly 9 of 10 teenagers have experienced cyberbullying, according to the.

Battling Multiple Chronic Illnesses Can Double Risk Of Depression

Drugs.com

MAY 21, 2025

WEDNESDAY, May 21, 2025 Battling chronic disease really takes it out of a person, leaving them vulnerable to depression.And people with multiple long-term health problems are even more likely to fall prey to depression, a new study says.Some c.

Disease

AI Can Catch Hard-To-Detect Breast Cancers In Mammograms

Drugs.com

MAY 14, 2025

WEDNESDAY, May 14, 2025 -- Artificial intelligence (AI) can help prevent breast cancers that develop between routine mammograms, by catching ones that trained radiologists would overlook, a new study says.Incorporating AI into mammography could.

New Molecular Test Could Double Leukemia Survival Rates

Drugs.com

MAY 5, 2025

MONDAY, May 5, 2025 Testing positive for leukemia actually saved the life of 51-year-old Jan Leahy, a business process owner from Wimbledon, England.Leahy benefitted from a clinical trial evaluating a new bone marrow test that can detect a p.

Clinical Trials

Clinical Trials Trials

Preemptive Kidney Transplants Add No Benefit, Study Says

Drugs.com

JUNE 4, 2025

WEDNESDAY, June 4, 2025 Folks who might need a kidney transplant in the future shouldnt rush to get one, a new study says.Patients gain no benefit from getting a donated kidney before their own kidneys deteriorate to the point that they require d.

Design, synthesis and biological evaluation of the activity-based probes for FGFR covalent inhibitor

Covalent Modifiers

MAY 25, 2025

Dandan Zhu, Zijian Zheng, Huixin Huang, Xiaojuan Chen, Shuhong Zhang, Zhuchu Chen, Ting Liu, Guangyu Xu, Ying Fu, Yongheng Chen, European Journal of Medicinal Chemistry , 2025 [link] Fibroblast growth factor receptors (FGFRs) represent promising therapeutic targets in various malignancies, yet the clinical application of FGFR covalent inhibitors has (..)

Drugs

Weight Gain, Delayed Motherhood Linked To Breast Cancer Risk

Drugs.com

MAY 14, 2025

WEDNESDAY, May 14, 2025 Significant weight gain paired with delayed or foregone motherhood nearly triples a young womans risk of later breast cancer, a new study says.Women were 2.7 times more likely to develop breast cancer if they:Had a more th.

How AI will reshape pharma by 2025

Ubrogepant (Ubrelvy) Effective Against Early Migraine Symptoms

Trending Sources

Fluoride Ban Could Create Cavities For 1 Of Every 3 U.S. Kids

FDA Limits COVID-19 Boosters to Seniors, Other High-Risk Groups

Bridging Innovation & Patient Care: The Growing Role of AI

GLP-1 Drugs Appear To Lower Cancer Risk

CDD Vault Update (May 2025): New PDB Viewer, AI Similarity Searches, Registered IDs in AI Results, Inventory Unit Conversion, Visualize Batch Data, Nucleotide to Amino Acid Sequence Translation

CDD Vault Update (April 2025 #3): AI+ Folding and Docking

Alzheimer’s Drug, Leqembi, Can Be Safely Administered In Memory Clinics, Study Says

Moderna's New Lower-Dose COVID-19 Vaccine, mNexspike, Approved by FDA

5 questions facing emerging biotech in 2025

Too Much Cinnamon May Interfere With Some Medications, Study Shows

More U.S. Teens Getting Weight-Loss Surgery

Florida-Grown Cucumbers Behind Salmonella Outbreak, CDC Warns

Sports, Exercise Protects Mental Health Of Growing Kids

Pepto Bismol May Not Prevent Traveler’s Diarrhea, New Study Finds

Coffee Could Be Key To Aging Gracefully

Drug Effective Against Early Migraine Symptoms

RFK Jr. Criticized for Swimming With Grandkids in Bacteria-Filled Creek

CDD Vault Update (March #2 2025): Macromolecule Atomistic Rendering, AI Datasets, Import Inventory Locations, Larger Inventory Boxes, Dark Mode

HHS, NIH Unveil Vaccine Initiative to Protect Against Future Pandemics

FDA Launches Postmarket Chemical Review Program to Ensure Food Safety

Blood, Urine Tests Can Identify Level Of Ultra-Processed Food In Diet

Troubled Kids Wait a Half-Day — Or More — In ER To Get Mental Health Care

FDA to Review and Possibly Ban Fluoride Supplements for Kids

Feeling Work Stress? Your Dog Might Be Feeling It Too

CDD Vault Update (April 2025 #2): Pharmacokinetic (PK) and Michaelis-Menten Kinetics (Km/Kd) Curve Fit Equations, Donut Charts, TIFF Image Previews, and Parallel Reactions

Drug Discovery Informatics for Big Pharma: Key Webinar Insights

Former President Joe Biden Diagnosed With Aggressive Prostate Cancer

Man Bitten by Snakes 200 Times May Help Create New Antivenom

Nebraska First State to Ban Soda, Energy Drinks From SNAP Program

New Drug Could Quell Uncontrolled High Blood Pressure

Fido Might Protect Your Baby Against Eczema

Doctors Perform First-Ever Human Bladder Transplant in U.S.

White House Report Blames Toxins, Food and Screens for Poor Health

Couch Potatoes Have Greater Risk Of Brain Decline, Even If They Exercise

Chemoselective Stabilized Triphenylphosphonium Probes for Capturing Reactive Carbonyl Species and Regenerating Covalent Inhibitors with Acrylamide Warheads in Cellulo

9 In 10 U.S. Teens Have Been Cyberbullied

Battling Multiple Chronic Illnesses Can Double Risk Of Depression

AI Can Catch Hard-To-Detect Breast Cancers In Mammograms

New Molecular Test Could Double Leukemia Survival Rates

Preemptive Kidney Transplants Add No Benefit, Study Says

Design, synthesis and biological evaluation of the activity-based probes for FGFR covalent inhibitor

Weight Gain, Delayed Motherhood Linked To Breast Cancer Risk

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