Collaborative Drug

FEBRUARY 21, 2025

CDD Update February 2025 #2 New Macromolecule Mode Edit DNA, RNA & Peptides with Bioconjugate Support

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RNA DNA 283

Drugs.com

MAY 15, 2025

THURSDAY, May 15, 2025 — The 2023 approval of the first drug shown to slow the progression of Alzheimer’s disease came with no small amount of concern from skeptics. Lecanemab (Leqembi) modestly slows Alzheimer’s by helping the.

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Drugs Disease 269

Drugs.com

MAY 14, 2025

WEDNESDAY, May 14, 2025 More U.S. teenagers are getting weight-loss surgery, despite the discovery of new drugs like Ozempic/Wegovy that help people drop pounds surgery-free, a new study says.Weight loss surgeries for teens increased 15% between 2.

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Drugs 243

Drugs.com

MAY 2, 2025

FRIDAY, May 2, 2025 -- The U.S. Department of Health and Human Services and the National Institutes of Health announced a new initiative called "Generation Gold Standard" to develop next-generation, universal vaccines using a beta-propiolactone.

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Vaccine 274

Drugs.com

MAY 14, 2025

WEDNESDAY, May 14, 2025 Exercise and sports appear to help kids avoid mental health problems as they grow into young adults, a new study says.Young children who participated in sports teams and physical education classes were less likely to d.

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BioPharma Drive: Drug Pricing

JANUARY 14, 2025

Young drugmakers confront several harsh realities this year, among them a contracting sector and competition from China.

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MAY 14, 2025

WEDNESDAY, May 14, 2025 -- Migraines dont just cause headaches.These attacks often are accompanied by symptoms like light and sound sensitivity, nausea, neck pain and dizziness.Whats more, those non-headache symptoms tend to crop up before a ful.

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Drugs 223

Drugs.com

MAY 14, 2025

WEDNESDAY, May 14, 2025 U.S. Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. is under fire after posting photos of himself and his grandchildren swimming in a long-polluted creek. The water at Rock Creek Park in Washington, D.C.,

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Collaborative Drug

MARCH 19, 2025

CDD Update March #2 2025 Full Atom Layout of Macromolecules New Dataset for AI Similarity Searching Import Inventory Locations by Unique Box Names:

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MAY 14, 2025

WEDNESDAY, May 14, 2025 The U.S. Food and Drug Administration (FDA) plans to review and possibly remove prescription fluoride supplements for children from the market.The FDA announced Tuesday that it intends to conduct the review by Oct.

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FDA Drugs 191

Drugs.com

MAY 5, 2025

MONDAY, May 5, 2025 Tim Friede has survived hundreds of snakebites on purpose. For nearly two decades, he let some of the worlds most dangerous snakes sink their fangs into his arms, all for science.Now, his bold experiment could potentially he.

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Collaborative Drug

MARCH 21, 2025

Our recent Q1 2025 scientific webinar brought together industry veterans Dr. Chris Waller and Dr. Dimitris Agrafiotis to discuss the current state and future directions of drug discovery informatics in large pharmaceutical organizations led by CDD's Founder and CEO, Dr.

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Drugs Pharmaceuticals 250

Collaborative Drug

APRIL 18, 2025

CDD Update March #2 2025 Full Atom Layout of Macromolecules New Dataset for AI Similarity Searching Import Inventory Locations by Unique Box Names:

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Pharmacokinetics 241

Collaborative Drug

APRIL 10, 2025

CDD Update March #2 2025 Full Atom Layout of Macromolecules New Dataset for AI Similarity Searching Import Inventory Locations by Unique Box Names:

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MAY 5, 2025

MONDAY, May 5, 2025 An experimental drug might help people with uncontrolled high blood pressure, according to early clinical trial results.People taking lorundrostat experienced twice the decline in their systolic blood pressure than people t.

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Drugs.com

MAY 19, 2025

MONDAY, May 19, 2025 -- Last week, the U.S. Food and Drug Administration announced a move to improve transparency and strengthen the safety of chemicals used in the nation's food supply.The agency is implementing an enhanced review process for food.

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Drugs.com

MAY 5, 2025

MONDAY, May 5, 2025 Testing positive for leukemia actually saved the life of 51-year-old Jan Leahy, a business process owner from Wimbledon, England.Leahy benefitted from a clinical trial evaluating a new bone marrow test that can detect a p.

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Clinical Trials Trials 179

Drugs.com

MAY 5, 2025

MONDAY, May 5, 2025 — An experimental drug might help people with uncontrolled high blood pressure, according to early clinical trial results. People taking lorundrostat experienced twice the decline in their systolic blood pressure than.

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Clinical Trials Drugs Trials 173

Covalent Modifiers

DECEMBER 28, 2024

Ai-Lin Chen, Zih-Jheng Lin, Hsiao-Yu Chang, and Tsung-Shing Andrew Wang Journal of the American Chemical Society , 2025 [link] Reactive carbonyl species (RCS) are important biomarkers of oxidative stress-related diseases because of their highly reactive electrophilic nature.

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Drugs.com

MAY 14, 2025

WEDNESDAY, May 14, 2025 -- Artificial intelligence (AI) can help prevent breast cancers that develop between routine mammograms, by catching ones that trained radiologists would overlook, a new study says.Incorporating AI into mammography could.

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MAY 14, 2025

WEDNESDAY, May 14, 2025 Significant weight gain paired with delayed or foregone motherhood nearly triples a young womans risk of later breast cancer, a new study says.Women were 2.7 times more likely to develop breast cancer if they:Had a more th.

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APRIL 25, 2025

FRIDAY, April 25, 2025 Novavaxs COVID-19 vaccine could soon receive full approval from the U.S. Food and Drug Administration (FDA), the company said Wednesday.The update sent Novavaxs stock up more than 21% in early trading. It also helped ease.

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FDA Approval Vaccine FDA Drugs 343

Drugs.com

MAY 5, 2025

MONDAY, May 5, 2025 Can gluten be passed on through a kiss?Its Its a concern for some folks with celiac disease, but a new study says worry not. People with celiac disease had no problems after kissing a partner whod just eaten a stack of saltine cr.

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Disease 162

Drugs.com

MAY 14, 2025

WEDNESDAY, May 14, 2025 Boston Celtics forward Jayson Tatum will miss the rest of the season after tearing his Achilles tendon. The team announced Tuesday that Tatum had surgery to repair the injury.Tatum, 27, was hurt in the fourth quarter of M.

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Drugs.com

MAY 19, 2025

MONDAY, May 19, 2025 Doctors in Southern California have performed the first human bladder transplant, offering new hope to people with serious bladder problems.The surgery was done earlier this month by two doctors from the University of C.

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Doctors 130

Drugs.com

MAY 19, 2025

MONDAY, May 19, 2025 Couch potatoes are more likely to develop Alzheimers disease, even if they set aside time to work out each day, a new study says.People who spent more time sitting around were more likely to experience cognitive decline and b.

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Disease 130

Drugs.com

MAY 19, 2025

MONDAY, May 19, 2025 Former President Joe Biden has been diagnosed with advanced prostate cancer that has spread to his bones, his office announced Sunday.Doctors found the cancer after Biden reported urinary symptoms. Testing showed a small n.

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Covalent Modifiers

APRIL 25, 2025

Seal, James Veccia, and Ku-Lung Hsu Journal of Medicinal Chemistry 2025 [link] Aldo-keto reductase family 1 member C3 (AKR1C3) is a member of the AKR superfamily of enzymes that metabolize androgen, estrogen, and prostaglandin substrates that drive proliferation in hormone-dependent cancers. Justin Grams, Wesley J. Wolfe, Robert J.

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Cell Biology 147

Drugs.com

MAY 19, 2025

MONDAY, May 19, 2025 Artificial intelligence (AI) can help detect when a persons multiple sclerosis (MS) has reached an advanced state, a new study says.A newly developed AI correctly judged with 90% accuracy when a persons MS had transitioned t.

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Drugs.com

MAY 19, 2025

MONDAY, May 19, 2025 (HealthDay New) Looking for a little uplift from Queens Dont Stop Me Now or Happy by Pharrell Williams?Or Or perhaps youre in a reflective mood and would rather hear Forever Young by Alphaville or Time After Time by Cyn.

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Covalent Modifiers

APRIL 13, 2025

2025 doi:10.26434/chemrxiv-2025-70x40. Waldmann H, Zhang R, liu J, Gasper R, Janning P. link] For targeted covalent protein modification at low reactivity aspartates and glutamates, new methods are in high demand.

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Covalent Modifiers

MAY 7, 2025

Xinyuan Wu, Jiayi Pan, Rufeng Fan, Yiwei Zhang, Chao Wang, Guoliang Wang, Jiaxiang Liu, Mengqing Cui, Jinfeng Yue, Rui Jin, Zhiqiang Duan, Mingyue Zheng, Lianghe Mei, Lu Zhou, Minjia Tan, Jing Ai, and Xiaojie Lu Journal of the American Chemical Society 2025 147 (18), 15469-15481 DOI: 10.1021/jacs.5c01712

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DNA Small Molecule Therapies Drugs 147

Drugs.com

MAY 5, 2025

MONDAY, May 5, 2025 -- Asthma attacks caused emergency room surges during the 2023 Canadian wildfires, with smoke-filled air sending hundreds to the hospital daily, a new study says.Daily asthma-related visits to Ontario hospitals increased nearly.

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Hospitals 130

Drugs.com

APRIL 25, 2025

FRIDAY, April 25, 2025 -- On Tuesday, the U.S. Department of Health and Human Services announced that the government will invest $176 million in Moderna to expedite the creation of a pandemic influenza vaccine, according to a report from the.

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Covalent Modifiers

APRIL 25, 2025

Cravatt Journal of the American Chemical Society 2025 DOI: 10.1021/jacs.5c01944 Cravatt, Timothy B. Ware, Alex Reed, Molhm Nassir, Tamara El-Hayek Ewing, Bruno Melillo, J. Fernando Bazan, Phil S. Baran, and Benjamin F.

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Covalent Modifiers

MAY 18, 2025

Nafizul Haque Kazi, Nikolas Klink, Kai Gallant, Gian-Marvin Kipka & Malte Gersch Nat Struct Mol Biol , 2025 [link] The mitochondrial deubiquitinase ubiquitin-specific protease (USP) 30 negatively regulates PINK1parkin-driven mitophagy.

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Engineering Regulations Small Molecule Clinical Trials 147

Covalent Modifiers

APRIL 20, 2025

Genhui Xiao, Yumeng Cui, Liangliang Zhou, Chuya Niu, Bing Wang, Jinglan Wang, Shaoyang Zhou, Miaomiao Pan, Chi Kin Chan, Yan Xia, Lan Xu, Yu Lu, Shawn Chen mLife , 2025 DOI: [link] The caseinolytic protease complex ClpP1P2 is crucial for protein homeostasis in mycobacteria and stress response and virulence of the pathogens.

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Small Molecule Drugs Research 147