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From siloed data to breakthroughs: multimodal AI in drug discovery

Drug Target Review

Multimodality however can detect and connect trends (and in future generate content) across different modalities and therefore allows for better interpretability, which builds trust between regulators, researchers and industry stakeholders. Compartmentalised teams struggle to fully leverage multimodality, leading to suboptimal solutions.

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The first major set of genetic associations found in long COVID

Drug Target Review

The study mentions the overlap in genes associated with Fatigue Dominant long COVID and ME/CFS, including those involved in circadian rhythm regulation and insulin regulation. She is a computational biologist with a background in bioprocess engineering and biotechnology.

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Next Generation Sequencing (NGS) in Clinical Trials: Challenges and Opportunities

Vial

The application of NGS has given researchers deep insights into genetic variation, gene expression, epigenetic modifications, alternative splicing, non-coding RNA regulation, microbial diversity, and various biological processes and diseases. In addition, NGS facilitates transcriptomics , epigenomics, metagenomics, and other omics studies.

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Amgen To Acquire Privately Held Teneobio For $900 Million In Cash With Future Contingent Milestone Payments

The Pharma Data

“Over the last five years, Teneobio developed leading-edge expertise in efficiently engineering differentiated multispecific and bispecific therapeutics for numerous indications with potentially better safety, efficacy and pharmacokinetic profiles than the first generation of T-cell engagers. chief executive officer of Teneobio.

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A quiet revolution in the world of proteomics

DrugBaron

But data is accumulating to suggest it matters a lot: resolving one variant from another – and understanding what drives their relative concentrations – may be just as important in biology as regulation of gene expression. Yet most modern proteomic protocols cannot readily distinguish thrombin from prothrombin or C3b from C3.

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Codon Digest: GPT-4 Controls a Robot

Codon

Codon Digest is my weekly roundup of research, news, and industry highlights about engineered biology. These microbes were engineered to express tumor antigens that could “elicit T cells that were licensed by the commensal immune program but specific for a tumor,” including both CD4+ and CD8+ T cells, according to the study.

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Is That DNA Dangerous?

Codon

And finally, people intent on causing harm could engineer pathogens to become more dangerous. But DNA screening tools can't simply flag any sequence that is similar to a potentially dangerous virus because the public databases also include engineered sequences comprising DNA sequences created from multiple different organisms.

DNA 105