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Advancing vaccine design: potential of peptide mimicry

Drug Target Review

In a new development, a recent paper published in Biology Methods & Protocols by Oxford University Press has highlighted a promising avenue for enhancing vaccine efficacy against infectious pathogens like the COVID-19 virus. Since December 2019, SARS-CoV-2 (COVID-19) infection has become a worldwide urgent public health concern.

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A chance to design better vaccines?

SCIENMAG: Medicine & Health

A new paper in Biology Methods & Protocols, published by Oxford University Press, shows it may be possible to design vaccines that will induce a stronger immune response to infecting pathogens, such as the virus causing COVID-19.

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Not all neoantigens are created equal

Drug Target Review

Recent advances in bioinformatics show clonal neoantigens are the best targets for immunotherapy, as I will elucidate below. Using powerful bioinformatics technology developed and validated with sequence data from the TRACERx study, researchers are able to identify clonal neoantigens from a patient’s unique tumour profile.

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In Silico Modeling Unveils a New Era in Rare Disease Drug Development

The Premier Consulting Blog

The information gleaned from these in silico models was used to design and test medicines against the virus, speed-up the vaccine discovery pipeline, predict any therapeutic failures, and minimize undesired effects. BMC Bioinformatics 2020, 21(Suppl 17):527 [link] Accessed April 4, 2023, at: [link] [2] Russo et al.

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Defense-Forward Biosecurity

Codon

While reading all the sequences present in a sample, researchers want to find any that are out of place, such as those that belong to a never-before-seen virus. New Yorkers wait to receive a monkeypox vaccine. This cleaning, annotation, and characterization work is all performed computationally.

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Monkey Embryos Grow to 25 Days — No Womb Required

Codon

link ) A phase I trial of a personalized neoantigen vaccine showed that they could boost T-cells and help fight off pancreatic tumors. Bioinformatics. Bioinformatics. This means that there’s no need to deliver the proteins at all; they are already lurking in the genome. Nature Communications. grams per liter titer.

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Monkey Embryos Grow to 25 Days — No Womb Required

Codon

link ) A phase I trial of a personalized neoantigen vaccine showed that they could boost T-cells and help fight off pancreatic tumors. Bioinformatics. Bioinformatics. This means that there’s no need to deliver the proteins at all; they are already lurking in the genome. Nature Communications. grams per liter titer.

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