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Life as Slime

Codon

Several decades of effort to create “artificial life” in the laboratory have produced biochemical machines and self-sustained protein production systems but, as yet, no organisms capable of cell division or robust metabolism. Biotechnologists know this firsthand. Thomas Moynihan is a historian and writer. Cite: Moynihan, T.

Science 96
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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

Read Maximizing protein production by keeping cells at optimal secretory stress levels using real-time control approaches. Read Modular metabolic engineering and synthetic coculture strategies for the production of aromatic compounds in yeast. (And Materials Today Bio. Read Living microecological hydrogels for wound healing.

DNA 52
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article thumbnail

Codon Digest: Discovering Antibiotics with Deep Learning

Codon

Read Maximizing protein production by keeping cells at optimal secretory stress levels using real-time control approaches. Read Modular metabolic engineering and synthetic coculture strategies for the production of aromatic compounds in yeast. (And Materials Today Bio. Read Living microecological hydrogels for wound healing.

DNA 52
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Toxic Proteins for Drug Discovery

Codon

Whiteman’s recent book is called “ Most Delicious Poison.” Ricin is toxic because it inactivates ribosomes, RNA-protein machines that translate each triplet codon of mRNA into its corresponding amino acid, linking them together to form peptides and proteins. In both cases, peptide and protein production stops.

Drugs 107
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The Codon Guide to Synthetic Biology

Codon

Link The PURE system for the cell-free synthesis of membrane proteins , by Kuruma Y. & Link An integrated cell-free metabolic platform for protein production and synthetic biology , by Jewett M.C. & Ueda T. Nature Protocols (2015). Molecular Systems Biology (2008). & Voigt C.A.

DNA 98
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The Codon Guide to Synthetic Biology

Codon

Link The PURE system for the cell-free synthesis of membrane proteins , by Kuruma Y. & Link An integrated cell-free metabolic platform for protein production and synthetic biology , by Jewett M.C. & Ueda T. Nature Protocols (2015). Molecular Systems Biology (2008).

DNA 52