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Levers for Biological Progress

Codon

Scientists are already building a model that can, for example, look at which RNA molecules are expressed in a cell at t=0 and predict how those molecules will change at t=1. Even more fundamentally, a virtual cell is a way to encapsulate the current extent of our biological knowledge. Even the humble E.

DNA 133
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New machine learning-based single-cell search engine makes cell annotation faster, more efficient

Broad Institute

Scientists then annotate the cells with this information, a process that can take days or even weeks, depending on the number of cells being labeled, and requires labor-intensive literature and database searches. We wanted to build a tool like that for cell biology. It’s basically a search engine.

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Women in STEM with Juliet Williams

Drug Target Review

Shortly after finishing my studies, I landed my first job in industry working on cell biology research for several disease indications. With these newer programs, I’ve had the honour of collaborating with my team to build a multi-faceted drug discovery engine.

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Cancer metastasis: breakthrough in therapeutic strategies

Drug Target Review

Researchers from the Keck School of Medicine of USC used imaging techniques to study how the protein GRP78 controls cancer cell behavior. In the top row, human lung cancer cells were engineered to over-express GRP78 in the nucleus. In the bottom row, cells lacked GRP78 in the nucleus.

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AI At The Frontier: Empowering Early Career Professionals In Drug Discovery

Elrig

She has played a key role inbuilding the target identification platform and a proprietary database of transcriptome-wide, functional RNA structures. Harini joined Serna Bio in early 2021 and has been an integral part of the multidisciplinary teamworking on target ID platform development to drug discovery.

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Fast Biology

Codon

My search made me appreciate how remarkable it is that life functions at all, considering the chaotic conditions in which cells exist. It also gave me a new appreciation for biology, and the incredible exactitude that one must have to engineer it — let alone engineer it successfully. of a Boeing 737 jet engine.

RNA 98
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Cell and gene therapy development moves into cardiac indications

Drug Target Review

The heart does have limited regenerative capacity, but not enough of the healthy cells that capable of restoring function, making it difficult to recover from injuries such as myocardial infarction. However, cell-based therapies are intended to leverage those healthy cells via transplant to regenerate damaged tissue.