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Automated red blood cell exchange: bridging treatment gaps in sickle cell disease care

Drug Target Review

Despite recent advances in gene therapy for sickle cell disease (SCD) , automated red blood cell exchange (aRBCX) remains a cornerstone therapy that plays a vital yet underutilised role in managing complications and enhancing quality of life for millions living with this devastating condition worldwide.

Disease 52
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The Long Road to End Tuberculosis

Codon

Physicians working in the early 20th century had little choice but to treat the world’s most rampant infectious disease with methods such as these. But even now, more than a century later, TB remains the deadliest infectious disease on Earth, killing about 1.2 million people every year.

Vaccine 114
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Giving Back: Once a Lung Transplant Recipient, Now a Surgical Nurse

The Pharma Data

30, 2020 — Nurses are known for being kind, caring and sympathetic, but Brianna Fogelman brings an uncommon empathy to her nursing job at Johns Hopkins Medicine in Baltimore. Though she had always planned to become a nurse, it wasn’t until after her transplant that it felt like more of a calling, Fogelman said.

Nurses 52
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Topical Gene Therapy FDA-Approved for Severe Skin Disease, Dystrophic Epidermolysis Bullosa

PLOS: DNA Science

Peter Marinkovich, MD, director of the Blistering Disease Clinic at Stanford Health Care, calls DEB a devastating disease. “Until now, doctors and nurses had no way to stop blisters and wounds from developing on dystrophic EB patient skin and all we could do was to give them bandages and helplessly watch as new blisters formed.

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Behçet’s Disease: Diverse manifestations in both brain and body

On Medicine

Behçet’s disease is a rare multisystem vasculitic disorder that can affect any of the blood vessels of the body; signs and symptoms are diverse among individuals and range in severity, but often present as recurrent oral aphthous ulcers, genital ulcers, or as complications involving the eyes.

Disease 40
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Mother of 4-Year-Old Living With KAND, One of the Rarest Disorders in the World, Advocates to Find a Cure

KIF1A

By ANDREA SWINDALL, First Published: 8:34 AM PDT, April 6, 2024 KIF1A Associated Neurological Disorder is a rare severe neurodegenerative disease caused by mutations in the KIF1A gene, Amanda Burrett says. We had her one-year checkup, and the doctor was concerned about her lack of awareness to the environment around her. Amanda says.

Doctors 52
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Heart Palpitations Can Be Common During Menopause

The Pharma Data

She’s an associate dean of research at Indiana University School of Nursing, in Indianapolis. Most of the time, doctors don’t see a woman with palpitations in isolation, but along with other symptoms, she said. We do often work these women up for heart disease because of these symptoms.

Doctors 52