Remove Disease Remove Protein Production Remove Small Molecule
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Eloxx Pharmaceuticals to Report Third Quarter 2020 Financial Results and Provide Business Update on November 5, 2020

The Pharma Data

is a clinical-stage biopharmaceutical company developing novel RNA-modulating drug candidates (designed to be eukaryotic ribosomal selective glycosides) that are formulated to treat rare and ultra-rare premature stop codon diseases. Premature stop codons are point mutations that disrupt protein synthesis from messenger RNA.

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A Look Back

Dark Matter Blog

My last stop at Arrakis Therapeutics is with a company targeting RNA with small molecules. I was enticed by Arrakis’ founder Jen Petter to serve in one more operational role, leading the research group at Arrakis as the company launched as one of the first biotechs to target RNA with drug-like small molecules.

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Targeting a human protein may stop Ebola virus in its tracks

The Pharma Data

Unfortunately, in a Phase 3 clinical trial, treatment with remdesivir did not make a difference in mortality for Ebola virus disease patients. Without the stop sign, viral transcription no longer follows the correct order, which has a negative impact on viral protein production,” says Fang.

Virus 52
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Codon Digest: Bacteria Resist Every Virus

Codon

Point-of-care peptide hormone production enabled by cell-free protein synthesis. Marine biofilm engineered to produce current in response to small molecules. Peroxisomal metabolic coupling improves fatty alcohol production from sole methanol in yeast. DeWinter MA. ACS Synthetic Biology. ACS Synthetic Biology.

Virus 52
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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

Read Programming inactive RNA-binding small molecules into bioactive degraders. Read Maximizing protein production by keeping cells at optimal secretory stress levels using real-time control approaches. Read Modular metabolic engineering and synthetic coculture strategies for the production of aromatic compounds in yeast.

DNA 52
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Codon Digest: Discovering Antibiotics with Deep Learning

Codon

Read Programming inactive RNA-binding small molecules into bioactive degraders. Read Maximizing protein production by keeping cells at optimal secretory stress levels using real-time control approaches. Read Modular metabolic engineering and synthetic coculture strategies for the production of aromatic compounds in yeast.

DNA 52
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What is Protein Nitration? | BMG LABTECH

BMG Labtech

The introduction of a nitro- group into a protein molecule is also implicated in different diseases including cardiovascular disease , lung disease, diabetes, cancer and some neurodegenerative conditions. It has been linked to the onset of several diseases and some examples are provided in the next section.