Disease Protein Production Small Molecule 
The Pharma Data
OCTOBER 14, 2020
is a clinical-stage biopharmaceutical company developing novel RNA-modulating drug candidates (designed to be eukaryotic ribosomal selective glycosides) that are formulated to treat rare and ultra-rare premature stop codon diseases. Premature stop codons are point mutations that disrupt protein synthesis from messenger RNA.
Dark Matter Blog
JULY 16, 2021
My last stop at Arrakis Therapeutics is with a company targeting RNA with small molecules. I was enticed by Arrakis’ founder Jen Petter to serve in one more operational role, leading the research group at Arrakis as the company launched as one of the first biotechs to target RNA with drug-like small molecules.
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The Pharma Data
MARCH 23, 2022
Unfortunately, in a Phase 3 clinical trial, treatment with remdesivir did not make a difference in mortality for Ebola virus disease patients. Without the stop sign, viral transcription no longer follows the correct order, which has a negative impact on viral protein production,” says Fang.
Codon
MARCH 20, 2023
Point-of-care peptide hormone production enabled by cell-free protein synthesis. Marine biofilm engineered to produce current in response to small molecules. Peroxisomal metabolic coupling improves fatty alcohol production from sole methanol in yeast. DeWinter MA. ACS Synthetic Biology. ACS Synthetic Biology.
Codon
MAY 30, 2023
Read Programming inactive RNA-binding small molecules into bioactive degraders. Read Maximizing protein production by keeping cells at optimal secretory stress levels using real-time control approaches. Read Modular metabolic engineering and synthetic coculture strategies for the production of aromatic compounds in yeast.
Codon
MAY 30, 2023
Read Programming inactive RNA-binding small molecules into bioactive degraders. Read Maximizing protein production by keeping cells at optimal secretory stress levels using real-time control approaches. Read Modular metabolic engineering and synthetic coculture strategies for the production of aromatic compounds in yeast.
BMG Labtech
FEBRUARY 24, 2025
The introduction of a nitro- group into a protein molecule is also implicated in different diseases including cardiovascular disease , lung disease, diabetes, cancer and some neurodegenerative conditions. It has been linked to the onset of several diseases and some examples are provided in the next section.
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