PLOS: DNA Science

MAY 4, 2023

Extracting information from her dental remains was possible because of the universality of the genetic code – in all organisms (and viruses), the same RNA triplets encode the same amino acids. .” The Red Lady was from a group of hunter-gatherers trapped in a cave. Here’s info from his notebooks.

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DNA Production RNA Science 52

Codon

AUGUST 27, 2024

Doctors in training are told that when they hear hoofbeats, they should think horses, not zebras; rare diseases are the exception, not the rule. While reading all the sequences present in a sample, researchers want to find any that are out of place, such as those that belong to a never-before-seen virus.

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DNA Laboratories Hospitals Virus 112

Broad Institute

JANUARY 30, 2024

He has also emerged in recent years as a skilled and relatable science communicator, renowned for his efforts at Broad and beyond during the COVID-19 pandemic to unpack the fast-moving research on the new virus in an accessible way and give practical advice about masking, vaccines, and other public health measures.

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Hospitals Virus Medical Schools Science 137

Codon

DECEMBER 12, 2024

Some scientists even think it had a virus defense system; “researchers say LUCA likely housed 19 CRISPR genes, which bacteria use to slice up viral threats,” reports Quanta Magazine. DNA and RNA molecules are also built from exclusively right-handed nucleic acids.

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RNA DNA Vaccine Virus 105

PLOS: DNA Science

OCTOBER 24, 2024

In those early days, politicians and government officials who’d never heard terms like “cytokine storm” and “RNA virus” were suddenly charged with explaining what was happening. But much of it was in the unfamiliar language of virology and immunology, public health and epidemiology.

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Science Research Vaccine Government 52

Codon

FEBRUARY 19, 2025

ESM is a protein language model that captures certain aspects of protein structure and function, for example, but is blind to DNA or RNA-level features that drive cell behavior. Evo 2 was trained on DNA sequences but can make predictions about myriad aspects of biology, including RNA stability and protein structures.

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DNA Laboratories Engineering RNA 107

The Pharma Data

NOVEMBER 18, 2020

Lab tests that look for the coronavirus’s genetic material using a technique called polymerase chain reaction (PCR) are still considered the gold standard for detecting the virus. That fragment sets off alarms in the immune system and stimulates it to attack if the real virus shows up. “I am hopeful that it works well.”

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FDA Approval FDA Vaccine Virus 52

The Pharma Data

NOVEMBER 17, 2020

After getting the virus under control, California Gov. Until now, Reynolds had ignored infectious disease experts who say masks are one of the most effective tools to control the spread of the virus, the Post reported. That fragment sets off alarms in the immune system and stimulates it to attack if the real virus shows up.

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Vaccine Virus RNA Hospitals 52

BioPharma Drive: Drug Pricing

JULY 10, 2025

Messenger RNA-based shots are especially in the spotlight, but even Novavax’s Nuvaxovid , a vaccine made with older technology, encountered delays. Recommended Reading Medical groups, pregnant doctor sue RFK Jr. The Centers for Disease Control and Prevention currently recommends shared clinical decision-making for healthy children.

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Vaccine FDA Therapies Licensing 226

Codon

JANUARY 26, 2025

The influenza virus was not isolated until 1933, when an epidemic in London enabled British researchers Wilson Smith, Christopher Andrewes, and Patrick Laidlaw to collect human influenza virus from patients’ throat washings. The inoculated eggs were incubated, allowing the virus to multiply. Subscribe to Asimov Press!

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Vaccine Virus Immune Response Clinical Trials 114

PLOS: DNA Science

FEBRUARY 20, 2025

Influenza incidence and severity are increasing , against a backdrop of novel drifts (small genetic changes) and shifts (larger changes) to the virus, all against a backdrop of novel infection pathways, such as birds to cows to people. The mRNA in COVID vaccines tells cells to produce the virus’s spike protein.

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Vaccine Science RNA Disease 91

Broad Institute

NOVEMBER 6, 2024

Doctors currently don’t have effective targeted treatments, so they often have to stop the anti-tumor therapy or give large amounts of steroids, which have their own undesired side effects such as lowering the efficacy of the ICI anti-tumor treatment. Tags: Cancer RNA sequencing Paper Cited Blum S, Zlotoff D, et al.

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Immune Response Medical Schools Clinical Trials Treatment 125

Codon

MAY 5, 2025

Educated in Vienna as a doctor of mechanical engineering and physics, Zippe’s passion was aeronautical engineering. This allowed for the isolation, purification, and study of minute amounts of DNA, RNA, proteins, and cells — tasks ill-suited to the larger centrifuges. But greater speed presented its own challenges.

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DNA Engineering Science Laboratories 58

NIH Director's Blog: Drug Development

JANUARY 5, 2016

This gene-editing system consists of a short segment of RNA that is attached to an enzyme. The RNA is preprogrammed to find a distinct short sequence of DNA and deliver the enzyme, which acts like a scalpel to slice the sequence out of the genome. 3] A Recombinant Vesicular Stomatitis Virus Ebola Vaccine — Preliminary Report.

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Vaccine Science Disease Engineering 52

The Pharma Data

DECEMBER 23, 2020

One person familiar with the list said it included the lipids that encase the RNA material in both the Moderna and Pfizer vaccines, the Times reported. Instead, it may have been identified there first because the British government has a strong monitoring system that has tracked tens of thousands of genomic sequences of virus samples.

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Vaccine Government Virus Medical Schools 52

The Pharma Data

NOVEMBER 9, 2020

With more people being exposed to the virus now, testing the vaccine becomes a speedier affair. The vaccine uses a technology never before used: Each injection contains lipid nanoparticles — fat bubbles — that surround a strip of genetic material called messenger RNA, the Post reported.

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Vaccine Virus RNA Trials 52

The Pharma Data

NOVEMBER 10, 2020

Eli Lilly has said it expects to have enough to treat 1 million people by the end of the year, not nearly enough to curb a virus that is now infecting an average of over 111,000 Americans a day, the Times reported. With more people being exposed to the virus now, testing the vaccine becomes a speedier affair.

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Treatment Vaccine Hospitals RNA 52

Codon

FEBRUARY 23, 2025

.” In 1974, Wolfram Ostertag , a German geneticist at the Max Planck Institute, explored whether zidovudine could block retroviruses , which carry RNA, and use a reverse transcriptase enzyme to convert it into DNA before integrating into the host genome. Researchers have instead focused on using antiretrovirals as preventives.

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Clinical Trials Virus Vaccine DNA 80