Thu.Oct 03, 2024

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Innovative Trials CEO named top Woman in Pharma at the Pharma Industry Awards UK

Drug Discovery Today

Kate Shaw, founder and CEO of Innovative Trials, a global clinical trial patient recruitment and retention company, has been crowned a top ‘Woman in Pharma’ at the Pharma Industry Awards UK. She was given the award at a ceremony in Birmingham on Wednesday 18th September.

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Wastewater bacteria can breakdown plastic for food

Science Daily: Pharmacology News

Comamonadacae is a family of bacteria often found growing on plastics in water. New study finds a bacterium in this family can break down the plastic for food. Researchers also identified the enzyme the bacterium use to degrade plastic. The discovery opens new possibilities for developing bacteria-based engineering solutions to help clean up difficult-to-remove plastic waste.

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Largest-ever genetic study of epilepsy finds possible therapeutic targets

Broad Institute

Largest-ever genetic study of epilepsy finds possible therapeutic targets By Ari Navetta October 3, 2024 Breadcrumb Home Largest-ever genetic study of epilepsy finds possible therapeutic targets Scientists have uncovered new genetic links to different types of epilepsy, which could lead to more tailored treatments. By Ari Navetta October 3, 2024 Credit: Ricardo Job-Reese, Broad Communications Related people Benjamin Neale Related programs Stanley Center for Psychiatric Research Related news DNA

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2-billion-year-old rock home to living microbes

Science Daily: Pharmacology News

Pockets of microbes have been found living within a sealed fracture in 2-billion-year-old rock. The rock was excavated from the Bushveld Igneous Complex in South Africa, an area known for its rich ore deposits. This is the oldest example of living microbes being found within ancient rock so far discovered. The team involved in the study built on its previous work to perfect a technique involving three types of imaging -- infrared spectroscopy, electron microscopy and fluorescent microscopy -- to

Research 133
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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New Viral Vectors - Fall 2024

addgene Blog

If the fall colors are inspiring you to paint your cells in equally vivid colors, you'll want to check out the 34 new preps available in the Addgene viral vector repository! This includes the first Addgene prep packaged in the AAV9-X1.1 serotype.

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The true global impact of species-loss caused by humans is far greater than expected

Science Daily: Pharmacology News

The extinction of hundreds of bird species caused by humans over the last 130,000 years has led to substantial reductions in avian functional diversity -- a measure of the range of different roles and functions that birds undertake within the environment -- and resulted in the loss of approximately 3 billion years of unique evolutionary history, according to a new study.

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Ant agriculture began 66 million years ago in the aftermath of the asteroid that doomed the dinosaurs

Science Daily: Pharmacology News

According to a new study, colonies of ants began farming fungi when an asteroid struck Earth 66 million years ago. This asteroid impact caused a global mass extinction but also created ideal conditions for fungi to thrive. Innovative ants began cultivating the fungi, creating an evolutionary partnership that became even more tightly intertwined 27 million years ago and continues to this day.

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FDA makes end of Zepbound, Mounjaro shortage official

BioPharma Drive: Drug Pricing

Removal of Lilly’s in-demand drugs from the FDA’s shortage list ramps up pressure on the companies selling compounded versions.

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Green subsidies may have hidden costs, experts warn

Science Daily: Pharmacology News

Government subsidies for business practices and processes should be approached with caution, even when they seem to be environmentally friendly, writes a group of scientists and economists. They argue that subsidies can alter market pressures, leading to unintended consequences that not only perpetuate harmful subsidies over time but also diminish the overall effectiveness of those intended to promote environmental sustainability.

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Record Rate of U.S. Kindergartners Failed to Get Recommended Vaccines

Drugs.com

THURSDAY, Oct. 3, 2024 -- In yet another sign that childhood vaccinations can't be taken for granted, new government data shows that a record number of kindergartners were exempted from the required shots during the last school year. That leaves.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Toddlers get nearly half their calories from ultra-processed foods

Science Daily: Pharmacology News

Toddlers in the UK obtain nearly half (47%) of their calories from ultra-processed foods (UPFs), and this rises to 59% by the age of seven, according to a new study. The most common UPFs consumed by the toddlers -- who were 21 months when their parents recorded their diets -- were flavored yogurts and wholegrain breakfast cereals, products typically seen as healthy.

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Stem Cell Therapy Might Repair Vision-Robbing Holes in Retinas

Drugs.com

THURSDAY, Oct. 3, 2024 -- Japanese researchers have successfully used a transplant of human stem cells to close a hole in a key part of a monkey's retina. They say the achievement could pave the way for better treatment of small gaps that form in.

Therapies 105
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Widespread ice deposits on the moon

Science Daily: Pharmacology News

Deposits of ice in lunar dust and rock (regolith) are more extensive than previously thought, according to a new analysis of data from NASA's LRO (Lunar Reconnaissance Orbiter) mission. Ice would be a valuable resource for future lunar expeditions. Water could be used for radiation protection and supporting human explorers, or broken into its hydrogen and oxygen components to make rocket fuel, energy, and breathable air.

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CDC Warns of Fake Drug Dangers From Online Pharmacies

Drugs.com

THURSDAY, Oct. 3, 2024 -- Americans who turn to online pharmacies to find cheaper versions of expensive prescription medications, especially opioids, may instead be buying themselves dangerous drugs that could trigger an overdose, U.S. health.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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In odd galaxy, NASA's Webb finds potential missing link to first stars

Science Daily: Pharmacology News

Looking deep into the early universe with NASA's James Webb Space Telescope, astronomers have found something unprecedented: a galaxy with an odd light signature, which they attribute to its gas outshining its stars. Found approximately one billion years after the big bang, galaxy GS-NDG-9422 (9422) may be a missing-link phase of galactic evolution between the universe's first stars and familiar, well-established galaxies.

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Reading to Your 1- and 2-Year Old Boosts Their Vocabulary, Study Finds

Drugs.com

THURSDAY, Oct. 3, 2024 -- Sharing a book with your baby will build her vocabulary fast, but time with screens likely won't, Norwegian researchers report. Their new study on shared reading and vocabulary size dovetails with a new policy statement.

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Stem cell transplants close macular holes in monkeys

Science Daily: Pharmacology News

Human stem cell transplants successfully repaired macular holes in a monkey model, researchers report. After transplantation, the macular holes were closed by continuous filling of the space with retinal tissue.

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Most Americans Struggle With Poor Sleep, Daytime Drowsiness: Survey

Drugs.com

THURSDAY, Oct. 3, 2024 -- Nearly 8 in 10 Americans go through the day in a fog that interferes with their jobs, their moods and their relationships. Chalk it up to sleepiness: A new survey shows that 54% of Americans think they just don't get.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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The Top 10 Longest-Running Drug Patents

Drug Patent Watch

Humira, used to treat various autoimmune diseases, has become the world’s best-selling drug. AbbVie has fiercely protected its patent through a strategy known as “patent thickets,” filing over 100 additional patents related to the drug’s manufacturing process, formulation, and methods of treatment[1].

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Sitting Less Helps Prevent Back Pain From Getting Worse

Drugs.com

THURSDAY, Oct. 3, 2024 -- Avoiding couches and chairs might be a good way of keeping your back pain from getting worse, new research suggests. Finnish researchers found that when people with back pain sat even a little less each day, their pain was.

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Turning brain cells on using the power of light

Science Daily: Pharmacology News

Researchers have developed a noninvasive way of using bioluminescent optogenetics to activate parts of the brain.

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Could Lithium Supplements Ease the Brain Fog of Long COVID?

Drugs.com

THURSDAY, Oct. 3, 22024 -- A small dose of the nutritional supplement lithium asparate may not ease the fatigue and brain fog of Long COVID, a small, new trial involving 52 patients has found. Still, it's possible that a larger dose of the.

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Recap of 2024 CDD European Life Science Community Meeting

Collaborative Drug

Celebrating 20 Years of Pioneering Drug Discovery and Collaboration: CDD User Group Meeting.

Science 110
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Science Finds Link Between Excessive Sweating, Sensitive Skin

Drugs.com

THURSDAY, Oct. 3, 2024 -- If you sweat excessively, you're likely to have sensitive skin as well, with new research confirming the two go hand-in-hand. A team led by Adam Friedman of George Washington University and Linqing Zhang of Virginia Tech.

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The Power of Human Tissue Models in Preclinical Research

Reprocell

This blog is the second in a series exploring the critical role of safety pharmacology in drug discovery. In our previous post, we discussed the importance of human tissue studies in ensuring drug safety. Today, we’ll dive into real-world case studies that highlight our innovative approaches and successes in utilizing human tissue models for safety assessment, demonstrating how these models have impacted drug development outcomes.

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Air Pollution Could Be Changing Children's Brains

Drugs.com

THURSDAY, Oct. 3, 2024 -- Even air pollution levels considered safe by U.S. standards appear to cause differences in the brains of growing children, a new review suggests. "We're seeing differences in brain outcomes between children with higher.

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Webinar Recap: Mastering Research Data Management for Startups

Collaborative Drug

Explore the impact of research data management on biotech R&D.

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Genome-Wide Association Studies (GWAS): A Refreshed Perspective

Broad Institute

Genome-Wide Association Studies (GWAS): A Refreshed Perspective By Rose Circeo October 3, 2024 Breadcrumb Home Genome-Wide Association Studies (GWAS): A Refreshed Perspective The Primer on Medical and Population Genetics is a series of weekly lectures on genetics topics related to human populations and disease. Experts from across the Medical and Population Genetics community at the Broad Institute give in-depth introductions to research in human genetics through overviews of core concepts and p

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September Monthly Momentum

KIF1A

September was packed with informational meetings, grant submissions, global connections with scientists, impact reports, awards, and outstanding community fundraising achievements! Keep reading to discover these amazing milestones and learn how you can get involved to make an IMPACT too! UPCOMING MEETINGS *Times are Eastern Time Zone. Oct 16 KIF1A.ORG Dylan Verden Office Hours These office hours provide an opportunity for you to bring any questions and discuss them in an open, informal setting.

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Enhance Self-Service Experience with ServiceNow Virtual Agent

Perficient: Drug Development

In today’s world, automation and self-service is all around us. From self-order tablets at restaurants to self-checkout lanes at grocery stores and self-check in kiosks at airports, the ability to complete tasks without requiring additional human assistance is incredibly valuable, saving both time and resources. For organizations utilizing ServiceNow as their IT Service Management (ITSM) platform, the ServiceNow Virtual Agent offers a powerful solution to streamline support and enhance the self-

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Good Friendships Crucial to Young Adults' Happiness, Study Finds

Drugs.com

THURSDAY, Oct. 3, 2024 -- If you're a 20-something who is unattached, having good friends is a key to happiness, new research shows. "The quality of your friendships is a key factor for your well-being, especially if you're single," a team led by.

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Q3 2024 Newsletter – Metabolism of degraders, gut metabolites, qNMR and more

Metabolite Tales Blog

Hypha’s Q3 2024 Newsletter – Metabolism of degraders, gut metabolites, qNMR and more Focus topics for this edition: Metabolism of targeted protein degraders drugs such as PROTACs. Novel fecal metabolites of inavolisib (GDC-0077). The role of NMR spectroscopy in drug metabolism studies. In the article we briefly discuss: ADME applications of NMR Use of 19 F-NMR and mass spec as an alternative to traditional ADME studies Cryoprobe technology Quantitative NMR Sign up at the bottom of t

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Antibodies in Mom's Breast Milk Are Protecting Babies

Drugs.com

THURSDAY, Oct. 3, 2024 (HeathDay News) -- Moms-to-be have long known about breast milk's multiple benefits. Now, a global study confirms that antibodies passed from to baby in breast milk can indeed shield against disease. Immune system antibodies.

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