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Elacestrant (6 R )-6-[2-[ethyl-[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydronaphthalen-2-ol (6R)-6-{2-[ethyl({4-[2-(ethylamino)ethyl]phenyl}methyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol FDA 1/27/2023, Orserdu WeightAverage: 458.646 Monoisotopic: 458.293328472 Chemical FormulaC 30 H 38 N 2 O 2 To treat estrogen receptor-positive, human epidermal growth factor receptor 2-negative, ESR1-mutated, advanced or metastatic breast cancer with disease
Some providers may need to reduce services, lay off staff or close their doors if Congress enacts major cuts to the safety-net insurance program, experts say.
Geographic Atrophy-Like Induced Model in Nanopigs iianiro Fri, 05/09/2025 - 13:00 Publication Poster_Altasciences_ARVO_2025Geographic Atrophy-Like Induced Model in Nanopigs.
New research shows that the gum disease bacterium P. gingivalis can slip into the bloodstream and infiltrate the heart. There, it quietly drives scar tissue buildup -- distorting the heart's architecture, disrupting electrical signals, and raising the risk of atrial fibrillation.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Evaluation in Canines of a Novel Device for Suprachoroidal Drug Delivery iianiro Fri, 05/09/2025 - 13:00 Publication Poster_Altasciences_ARVO_2025Evaluation in Canines of a Novel Device for Suprachoroidal Drug Delivery_1.
Millions of kilometers of rivers around the world are carrying antibiotic pollution at levels high enough to promote drug resistance and harm aquatic life, a new study warns. The study estimated the scale of global river contamination from human antibiotics use. Researchers calculated that about 8,500 tons of antibiotics -- nearly one-third of what people consume annually -- end up in river systems around the world each year even after in many cases passing through wastewater systems.
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Millions of kilometers of rivers around the world are carrying antibiotic pollution at levels high enough to promote drug resistance and harm aquatic life, a new study warns. The study estimated the scale of global river contamination from human antibiotics use. Researchers calculated that about 8,500 tons of antibiotics -- nearly one-third of what people consume annually -- end up in river systems around the world each year even after in many cases passing through wastewater systems.
Geographic Atrophy-Like Induced Model in Nanopigs iianiro Fri, 05/09/2025 - 13:00 Publication Poster_Altasciences_ARVO_2025Geographic Atrophy-Like Induced Model in Nanopigs_0.
New research from a team of cognitive scientists and evolutionary biologists finds that chimpanzees drum rhythmically, using regular spacing between drum hits. Their results show that eastern and western chimpanzees -- two distinct subspecies -- drum with distinguishable rhythms. The researchers say these findings suggest that the building blocks of human musicality arose in a common ancestor of chimpanzees and humans.
FRIDAY, May 9, 2025 The U.S. Food and Drug Administration (FDA) is warning consumers and tattoo artists that two tattoo inks have tested positive for harmful bacteria and could lead to serious infections.The affected products are:Sacred Tattoo I.
Wild chimpanzees alter the meaning of single calls when embedding them into diverse call combinations, mirroring linguistic operations in human language. Human language, however, allows an infinite generation of meaning by combining phonemes into words and words into sentences. This contrasts with the very few meaningful combinations reported in animals, leaving the mystery of human language evolution unresolved.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
FRIDAY, May 9, 2025 Childhood obesity nearly triples a persons risk for experiencing discrimination or stigma based on their weight, a new study says.Severe obesity before age 18 increased a persons odds of experiencing weight stigma by 2.8 time.
Researchers have developed two unique energy-efficient and cost-effective systems that use urea found in urine and wastewater to generate hydrogen. The unique systems reveal new pathways to economically generate 'green' hydrogen, a sustainable and renewable energy source, and the potential to remediate nitrogenous waste in aquatic environments.
FRIDAY, May 9, 2025 More talk and fewer pills are being employed to help Americans maintain their mental health, a new study says.Psychotherapy is assuming a larger role in mental health care, while medications prescribed without accompanying t.
An international team has pioneered a nano-3D printing method to create superconducting nanostructures, leading to groundbreaking technological advancements.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
FRIDAY, May 9, 2025 More young adults in the U.S. are being diagnosed with cancer, and researchers are trying to figure out why.A new government report shows that rates of several types of cancer are going up in people under age 50, especially a.
The big pharma will spend up to $250 million over the next eight years of the collaboration. Elsewhere, CRISPR Therapeutics unveiled new data and Vivo Capital raised funds.
FRIDAY, May 9, 2025 Blood tests could catch as many as half of cancers at an earlier, more treatable stage, a new study says.If conducted every year or every other year, the multi-cancer early detection (MCED) blood test could help more people s.
Gene therapy offers a one-off treatment that tackles the underlying mutation causing an illness or medical condition. By using adeno-associated virus (AAV) vectors to deliver a functional copy of the faulty gene to liver cells, patients begin producing their own clotting factoreither factor VIII for hemophilia A or factor IX for hemophilia B. Human gene therapy clinical trials show promising results of durable factor expression s and far fewer bleeds within these patient groups.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
FRIDAY, May 9, 2025 -- Smoking can't explain why women are more at risk for COPD, a new study says.Women are about 50% more likely than men to develop COPD even though they are less likely to smoke, researchers reported May 8 in the journal BMJ.
Clofutriben Cas 1204178-50-6 HCL 1203941-88-1 ASP 3662 4-(5-(2-(4-Chloro-2,6-difluorophenoxy)propan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl)-3-fluorobenzamide 4-{5-[2-(4-Chloro-2,6-difluorophenoxy)propan-2-yl]-4-methyl-4H-1,2,4-triazol-3-yl}-3-fluorobenzamide 4-[5-[2-(4-chloro-2,6-difluorophenoxy)propan-2-yl]-4-methyl-1,2,4-triazol-3-yl]-3-fluorobenzamide 4L1TY1U5VC Molecular Weight 424.80 Formula C 19 H 16 ClF 3 N 4 O 2 Clofutriben (ASP3662) is a 11-hydroxysteroid dehydrogenase type 1 inhibitor.
In times of geopolitical tension, especially between nations like India and Pakistan, the possibility of conflicthowever unlikelycan spark fear and confusion. While we all hope for peace, it’s wise to prepare for emergencies with a calm, practical mindset. Whether you are a parent, a professional, or both, readiness can offer a sense of control and security during uncertain times.
In the ever-evolving pharmaceutical landscape, biotech and biopharma organizations continue to embrace the critical importance of functional service provider (FSP) outsourcing. The PPD clinical research business of Thermo Fisher Scientific conducted its third annual Pulse Report a survey of 150 leaders from biotech and pharmaceutical organizations worldwide.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
With a month to go before Contact Center Week, the largest CCW event to date in Las Vegas, we took a moment to sit down with Colleen Eager, a senior solutions architect to learn how to navigate this conference. She’s here to help you stay focused on what matters most, and understands that its easy to get overwhelmed by the volume of information, resources, technologies and vendors that will be present at the show.
Accurate and accessible medical information is a cornerstone of patient safety, satisfaction and better health outcomes. Empowering patients to access information in their preferred way whether through automation, live interactions or other methods improves the effectiveness of medical communications. As technology advances, patients naturally expect faster, more accurate and personalized service.
The bone marrow niche is a dynamic microenvironment essential for maintaining hematopoietic stem and progenitor cells (HSPCs). Understanding the molecular and cellular mechanisms in the bone marrow niche provides valuable insights for therapeutic interventions. The interplay between stromal cells, extracellular matrix components, and signaling pathways within the niche not only affects normal hematopoiesis but also contributes to tumor progression, drug resistance, and metastasis in hematologica
Asking questions about data has been part of Oracle Analytics through the homepage search bar for several years now. It did that with Natural Language Processing (NLP) to respond to questions with various automatically generated visualizations. What has been introduced since late 2024 is the capability to leverage Large Language Models (LLM) to respond to user questions and commands from within a Workbook.
AuthoritativeregulationsshapingHerbalClinicalTrialsinIndia,detailingAYUSHprotocols,CDSCOmandates,andGCPstandardstoupholdscientificrigorandregulatoryexcellence. India, the cradle of Ayurveda and centuries-old herbal traditions, is rapidly emerging as a global leader in evidence-based herbal medicine. With the increasing demand for natural therapies backed by […] The post Follow These Regulations for Herbal Clinical Trials in India appeared first on ProRelix Research.
FRIDAY, May 9, 2025 Women with common autoimmune inflammatory diseases are more likely than men to die from heart disease, a new study says.Women with rheumatoid arthritis, lupus or systemic sclerosis have a 50% higher heart disease-related death.
FRIDAY, May 9, 2025 Removal of the ovaries and fallopian tubes appears to dramatically reduce the risk of death among breast cancer survivors who are genetically prone to cancer, a new study says.Breast cancer survivors carrying BRCA1 and BRCA2 g.
FRIDAY, May 9, 2025 President Donald Trump has chosen Dr. Casey Means, a wellness influencer and health tech entrepreneur, to be his nominee for U.S. surgeon general.The decision comes after Trump withdrew his previous nominee, Dr. Janette N.
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