Sun.Apr 07, 2024

article thumbnail

New patent expiration for Salix Pharms drug RELISTOR

Drug Patent Watch

Annual Drug Patent Expirations for RELISTOR Relistor is a drug marketed by Salix Pharms and Salix and is included in two NDAs. It is available from one supplier.

Drugs 98
article thumbnail

Fitting of kinact and KI Values from Endpoint Pre-incubation IC50 Data

Covalent Modifiers

Lavleen K. Mader and Jeffrey W. Keillor ACS Medicinal Chemistry Letters 2024 DOI: 10.1021/acsmedchemlett.4c00054 Experiments comprising a “pre-incubation” phase, where enzyme is incubated with inhibitor prior to the addition of assay substrate, are commonly used to evaluate covalent inhibitors, often via discontinuous or “endpoint” IC50 assays. However, due to the lack of mathematical tools to describe its biphasic time-dependent nature, this experiment has thus far been unable to provide kinact

66
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

New patent expiration for Insmed Inc drug ARIKAYCE KIT

Drug Patent Watch

Annual Drug Patent Expirations for ARIKAYCE+KIT Arikayce Kit is a drug marketed by Insmed Inc and is included in one NDA. It is available from one supplier.

Drugs 52
article thumbnail

Which pharmaceutical companies have the most drug patents in Japan?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in Japan.

article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.