Mon.Jun 16, 2025

article thumbnail

Single psilocybin trip delivers two years of depression relief for cancer patients

Science Daily: Pharmacology News

Psilocybin, the active ingredient in magic mushrooms, might just revolutionize how depression and anxiety are treated in cancer patients. In a groundbreaking trial, a single dose combined with therapy significantly reduced emotional suffering, and these effects often lasted over two years. As follow-up studies expand the research to multiple doses and larger samples, scientists are eyeing a possible new standard of care that merges psychedelics with psychological support.

Therapies 256
article thumbnail

Texas Invests $50M in Psychedelic Drug Research into Ibogaine to Treat Addiction

Drugs.com

MONDAY, June 16, 2025 — Texas has moved to fund research into ibogaine, a psychedelic drug that may help treat addiction, depression, and brain injuries. Gov. Greg Abbott signed a bill last week approving $50 million in state funds for.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction

Covalent Modifiers

Dhirendra K. Simanshu, Rui Xu, James P. Stice, Daniel J. Czyzyk, Siyu Feng, John-Paul Denson, Erin Riegler, Yue Yang, Cathy Zhang, Sofia Donovan, Brian P. Smith, Maria Abreu-Blanco, Ming Chen, Cindy Feng, Lijuan Fu, Dana Rabara, Lucy C Young, Marcin Dyba, Wupeng Yan, Ken Lin, Samar Ghorbanpoorvalukolaie, Erik K. Larsen, Wafa Malik, Allison Champagne, Katie Parker, Jin Hyun Ju, Stevan Jeknic, Dominic Esposito, David M.

Science 130
article thumbnail

COVID Vaccine Protects Against Kidney Damage During Infection

Drugs.com

MONDAY, June 16, 2025 — Kidney damage is common during a severe case of COVID-19, but vaccination appears to protect people against this life-threatening side effect, a new study says. Unvaccinated COVID patients with kidney damage severe enough to.

Vaccine 248
article thumbnail

Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

article thumbnail

CDD Vault Curves vs. GraphPad Prism: Which Tool is Best for Early-Stage Drug Discovery Data Analysis?

Collaborative Drug

Compare CDD Vault Curves vs GraphPad Prism for drug discovery data analysis. See which tool best fits your workflow for curve fitting and collaboration.

Drugs 147
article thumbnail

Your brain has a hidden beat — and smarter minds sync to it

Science Daily: Pharmacology News

When we focus, switch tasks, or face tough mental challenges, the brain starts to sync its internal rhythms, especially in the midfrontal region. A new study has found that smarter individuals show more precise and flexible coordination of slow theta waves during key decision-making moments. Using EEG recordings and cognitive testing, researchers discovered that it s not constant brainwave synchronization that matters most, but the brain s ability to dynamically adapt its rhythms like a well-tun

More Trending

article thumbnail

These beetles can see a color most insects can’t

Science Daily: Pharmacology News

Beetles that can see the color red? That s exactly what scientists discovered in two Mediterranean species that defy the norm of insect vision. While most insects are blind to red, these beetles use specialized photoreceptors to detect it and even show a strong preference for red flowers like poppies and anemones. This breakthrough challenges long-standing assumptions about how flower colors evolved and opens a new path for studying how pollinators influence plant traits over time.

194
194
article thumbnail

Why We Committed to Amazon Web Services — And What It Means for You

Collaborative Drug

CDD Vault migrates to AWS for enhanced security, global performance, and scalable infrastructure supporting drug discovery research worldwide.

Research 147
article thumbnail

New COVID Variant, NB.1.8.1, May Now Make Up 1 in 3 U.S. Cases

Drugs.com

MONDAY, June 16, 2025 — A new COVID-19 variant that led to a spike in hospital cases across parts of Asia may now account for more than one-third of all COVID cases in the U.S., health officials say.The variant, known as NB.1.8.1, has been s.

Hospitals 247
article thumbnail

Monster salamander with powerful jaws unearthed in Tennessee fossil find

Science Daily: Pharmacology News

A massive, extinct salamander with jaws like a vice once roamed ancient Tennessee and its fossil has just rewritten what we thought we knew about Appalachian amphibians. Named Dynamognathus robertsoni, this powerful predator wasn t just a curiosity; it may have sparked an evolutionary chain reaction, shaping the region s remarkably diverse salamander population.

209
209
article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

ADHD Stimulants Can Be Safely Prescribed Via Telehealth, Study Argues

Drugs.com

MONDAY, June 16, 2025 — People with ADHD might be prescribed their meds remotely without increasing their risk of addiction, a new study says.Experts have worried that prescribing stimulants like Adderall through telehealth visits might increase s.

168
168
article thumbnail

Cluck once, and the river shakes: Inside the Amazon’s giant snake saga

Science Daily: Pharmacology News

A lifelong fascination with nature and fieldwork led this researcher to the world of ethnobiology a field where ecology, culture, and community come together. Investigating how local people relate to species like the anaconda, their work blends traditional knowledge with scientific methods for better conservation. The tale of the mythic Great Snake morphs into economic concerns over vanishing chickens, revealing how cultural beliefs and practical needs coexist.

Research 175
article thumbnail

Rheumatoid Arthritis On The Rise Worldwide, AI-Powered Study Estimates

Drugs.com

MONDAY, June 16, 2025 — Rheumatoid arthritis (RA) has steadily increased around the world during the past three decades, a new AI-powered study reports.The autoimmune disease affected 17.9 million people worldwide in 2021, a 13% increase from 1990.

Disease 180
article thumbnail

MIT uncovers the hidden playbook your brain uses to outsmart complicated problems

Science Daily: Pharmacology News

When faced with a tricky maze task involving hidden information, humans instinctively toggle between two clever mental strategies: simplifying in steps or mentally rewinding. MIT researchers showed that people shift methods based on how reliable their memory is echoed by AI models mimicking the same constraints.

Research 169
article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Innovative Once-Weekly Capsule Helps Quell Schizophrenia Symptoms

Drugs.com

MONDAY, June 16, 2025 — A new breakthrough can help people with schizophrenia keep up with their psychiatric meds, researchers said.A pill taken just once a week, gradually releasing medicine from within the stomach, can greatly simplify the drug s.

Research 154
article thumbnail

Forever chemicals' toxic cousin: MCCPs detected in U. S. air for first time

Science Daily: Pharmacology News

In a surprising twist during an air quality study in Oklahoma, researchers detected MCCPs an industrial pollutant never before measured in the Western Hemisphere's atmosphere. The team suspects these toxic compounds are entering the air through biosolid fertilizers derived from sewage sludge. While these pollutants are not yet regulated like their SCCP cousins, their similarity to dangerous "forever chemicals" and unexpected presence raise red flags about how chemical substitutions and waste dis

article thumbnail

Generic Drug Entry Timeline: Predicting Market Dynamics After Patent Loss

Drug Patent Watch

"The Patent Cliff: A Looming Tsunami for Big Pharma As the pharmaceutical industry stands at the precipice of a seismic shift, one question looms large: what happens when the patents expire? A new analysis from Drug Patent Watch reveals the hidden timeline behind generic drug entry, and the market dynamics that will be reshaped in its wake.

article thumbnail

600-million-year-old body blueprint found in sea anemones

Science Daily: Pharmacology News

Sea anemones may hold the key to the ancient origins of body symmetry. A study from the University of Vienna shows they use a molecular mechanism known as BMP shuttling, once thought unique to bilaterally symmetrical animals like humans, insects, and worms. This surprising discovery implies that the blueprint for forming a back-to-belly body axis could date back over 600 million years, to a common ancestor of cnidarians and bilaterians.

160
160
article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

How GPCR-targeting therapies are advancing the fight against inflammatory disease

Drug Target Review

G protein-coupled receptors (GPCRs) are a highly validated drug target family – accounting for 30-35 percent of all approved drugs. Despite this, the therapeutic potential of targeting most GPCRs remains untapped, as only 10 percent of GPCRs have been drugged. In this article, Stephan Schann, Chief Scientific Officer at Domain Therapeutics , explains why this class of drug target is so useful despite the challenges they present.

Disease 59
article thumbnail

Saving energy: New method guides magnetism without magnets

Science Daily: Pharmacology News

In a leap toward greener tech, researchers at the Paul Scherrer Institute have discovered a way to control magnetic textures using electric fields no bulky magnets needed. Their star material? A strange crystal called copper oxyselenide, where magnetic patterns like helices and cones swirl at low temperatures. By zapping it with different electric fields, they could bend, twist, and even flip these patterns a first in the world of magnetoelectrics.

Research 114
article thumbnail

A spatial approach to understanding drug dynamics using mass spectrometry imaging

Drug Target Review

Mass spectrometry imaging (MSI) enables the direct detection and quantitation of active pharmaceutical ingredients (APIs) and metabolites within tissue sections, making it widely regarded as a promising technique in the field of pharmacology and toxicology. Unlike traditional pharmacokinetic (PK) studies that rely on plasma measurements alone, MSI, when combined with traditional histology, enables spatial mapping of drug distribution, metabolism and target engagement.

Drugs 52
article thumbnail

Clever worms form superorganism towers to hitch rides on insects

Science Daily: Pharmacology News

Nematodes tiny yet mighty form wriggling towers to survive and travel as a team. Long thought to exist only in labs, scientists have now spotted these towers naturally forming in rotting orchard fruit. Remarkably, the worms aren t just piling up they build responsive, coordinated structures that hitch rides on insects to escape harsh conditions.

131
131
article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

Children With MS Age Faster, Study Says

Drugs.com

MONDAY, June 16, 2025 — Kids with multiple sclerosis (MS) age at an accelerated rate as the disease causes advanced wear and tear on their bodies, a new study says.This accelerated aging extends into their teenage years, increasing their odds that M.

Disease 130
article thumbnail

Rainbow reefs revealed: The secret 112-million-year saga of glowing fish

Science Daily: Pharmacology News

Scientists have uncovered that fish biofluorescence a captivating ability to glow in vivid colors has ancient roots stretching back over 100 million years. This trait evolved independently in reef fish more than 100 times, likely influenced by post-dinosaur-extinction reef expansion. The glowing spectacle is more diverse than previously imagined, spanning multiple colors across hundreds of species.

131
131
article thumbnail

How EDC-Based SAE Reporting Reduces Time to Detection and Response in Clinical Trials

Crucial Data Solutions

Serious adverse events (SAEs) are among the most critical data points collected during a clinical trial. The timeliness and accuracy. The post How EDC-Based SAE Reporting Reduces Time to Detection and Response in Clinical Trials appeared first on Crucial Data Solutions.

article thumbnail

Cozmic’s Milky Way clones are cracking the universe’s dark code

Science Daily: Pharmacology News

Scientists have built detailed Milky Way simulations under strange new physical laws to probe dark matter, revealing how different versions of the universe might behave and helping us get closer to the real one.

119
119
article thumbnail

Agenda

Broad Institute

Agenda By Rose Circeo June 16, 2025 Breadcrumb Home Agenda Day 1, November 6, 2025 12:00 - 5:00 pm Workshop Day 2, November 7, 2025 8:00 - 6:00 pm Symposium Symposium 8:00 - 9:00 am Registration and Breakfast Opening Session 9:00 - 9:10 am Welcome Sumaiya Iqbal Broad Institute 9:10 - 9:25 am Opening Remarks and Keynote Introduction Stacey Gabriel Broad Institute Keynote 9:30 - 10:30 am Keynote Thomas Miller Iambic Therapeutics Morning Session Chair: Sumaiya Iqbal 10:30 - 11:10 am AI for Patient

article thumbnail

Heavy particles, big secrets: What happened right after the Big Bang

Science Daily: Pharmacology News

Smashing atomic nuclei together at mind-bending speeds recreates the fiery conditions of the early universe and scientists are finally getting a better handle on what happens next. A sweeping new study dives deep into how ultra-heavy particles behave after these high-energy collisions, revealing they don t just vanish after the initial impact but continue interacting like silent messengers from the dawn of time.

119
119
article thumbnail

Teva and Fosun Partner to Develop Novel Anti-PD1-IL2 Immunotherapy

The Pharma Data

Teva and Fosun Pharma Forge Strategic Partnership to Develop and Commercialize Innovative Anti-PD1-IL2 Therapy (TEV-56278) in Immuno-Oncology Teva Pharmaceutical Industries Ltd. and Shanghai Fosun Pharmaceutical (Group) Co., Ltd. today announced a significant strategic partnership for the development and eventual commercial delivery of TEV-56278 , a novel investigational anti-PD1-IL2 ATTENUKINE therapy with the potential to transform the way many forms of cancer are treated.

article thumbnail

#WhyIScienceQ&A: A neuroscientist advocates for stepping outside your comfort zone in research

Broad Institute

#WhyIScienceQ&A: A neuroscientist advocates for stepping outside your comfort zone in research By Allessandra DiCorato June 16, 2025 Breadcrumb Home #WhyIScienceQ&A: A neuroscientist advocates for stepping outside your comfort zone in research Giulia Monti reflects on how studying Alzheimer’s disease alongside researchers focused on kidney disease has helped her grow as a scientist.

article thumbnail

BMS Presents Transcend FL Data: Breyanzi Shows Durable Responses in Marginal Zone Lymphoma

The Pharma Data

Bristol Myers Squibb Presents Positive Transcend FL Data Highlighting Durable Responses with Breyanzi in Relapsed or Refractory Marginal Zone Lymphoma Bristol Myers Squibb today announced the first disclosure of the primary analysis results from the marginal zone lymphoma (MZL) cohort of its TRANSCEND FL trial — a Phase 2, open-label, global, multicenter, single-arm study evaluating Breyanzi (lisocabtagene maraleucel; liso-cel) in patients with relapsed or refractory MZL.

article thumbnail

How Inclusive Design Leading and Creating Solutions for Universal Design

Perficient: Drug Development

In the world of design, the relationship between Inclusive Design and Universal Design is often misunderstood. While they share the goal of creating usable and accessible experiences , Inclusive Design focuses on offering multiple solutions for diverse needs , while Universal Design refines those solutions into seamless experiences that work for everyone.