Covalent Modifiers

JUNE 16, 2025

Dhirendra K. Simanshu, Rui Xu, James P. Stice, Daniel J. Czyzyk, Siyu Feng, John-Paul Denson, Erin Riegler, Yue Yang, Cathy Zhang, Sofia Donovan, Brian P. Smith, Maria Abreu-Blanco, Ming Chen, Cindy Feng, Lijuan Fu, Dana Rabara, Lucy C Young, Marcin Dyba, Wupeng Yan, Ken Lin, Samar Ghorbanpoorvalukolaie, Erik K. Larsen, Wafa Malik, Allison Champagne, Katie Parker, Jin Hyun Ju, Stevan Jeknic, Dominic Esposito, David M.

Science

The Pharma Data

JUNE 16, 2025

Teva and Fosun Pharma Forge Strategic Partnership to Develop and Commercialize Innovative Anti-PD1-IL2 Therapy (TEV-56278) in Immuno-Oncology Teva Pharmaceutical Industries Ltd. and Shanghai Fosun Pharmaceutical (Group) Co., Ltd. today announced a significant strategic partnership for the development and eventual commercial delivery of TEV-56278 , a novel investigational anti-PD1-IL2 ATTENUKINE therapy with the potential to transform the way many forms of cancer are treated.

Therapies

Drug Target Review

JUNE 16, 2025

Mass spectrometry imaging (MSI) enables the direct detection and quantitation of active pharmaceutical ingredients (APIs) and metabolites within tissue sections, making it widely regarded as a promising technique in the field of pharmacology and toxicology. Unlike traditional pharmacokinetic (PK) studies that rely on plasma measurements alone, MSI, when combined with traditional histology, enables spatial mapping of drug distribution, metabolism and target engagement.

Drugs

Science Daily: Pharmacology News

JUNE 16, 2025

Psilocybin, the active ingredient in magic mushrooms, might just revolutionize how depression and anxiety are treated in cancer patients. In a groundbreaking trial, a single dose combined with therapy significantly reduced emotional suffering, and these effects often lasted over two years. As follow-up studies expand the research to multiple doses and larger samples, scientists are eyeing a possible new standard of care that merges psychedelics with psychological support.

Therapies

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

Clinical Trials

Drug Target Review

JUNE 16, 2025

G protein-coupled receptors (GPCRs) are a highly validated drug target family – accounting for 30-35 percent of all approved drugs. Despite this, the therapeutic potential of targeting most GPCRs remains untapped, as only 10 percent of GPCRs have been drugged. In this article, Stephan Schann, Chief Scientific Officer at Domain Therapeutics , explains why this class of drug target is so useful despite the challenges they present.

Disease

The Pharma Data

JUNE 16, 2025

Bristol Myers Squibb Presents Positive Transcend FL Data Highlighting Durable Responses with Breyanzi in Relapsed or Refractory Marginal Zone Lymphoma Bristol Myers Squibb today announced the first disclosure of the primary analysis results from the marginal zone lymphoma (MZL) cohort of its TRANSCEND FL trial — a Phase 2, open-label, global, multicenter, single-arm study evaluating Breyanzi (lisocabtagene maraleucel; liso-cel) in patients with relapsed or refractory MZL.

Therapies

The Pharma Data

JUNE 16, 2025

WuXi AppTec Recognized Among Top 10 “Most Honored Companies” in Extel 2025 Asia Executive Team Rankings, Continuing its Global Leadership in Innovation and Drug Discovery Services WuXi AppTec , a leading global company that provides a broad portfolio of research and manufacturing services designed to enable companies in the pharmaceutical and life sciences sectors, has been recognized among the Top 10 “Most Honored Companies” in the new Extel 2025 Asia Executive Team Rankings.

Government

Drug Patent Watch

JUNE 16, 2025

"The Patent Cliff: A Looming Tsunami for Big Pharma As the pharmaceutical industry stands at the precipice of a seismic shift, one question looms large: what happens when the patents expire? A new analysis from Drug Patent Watch reveals the hidden timeline behind generic drug entry, and the market dynamics that will be reshaped in its wake.

Marketing

The Pharma Data

JUNE 16, 2025

Roche Advances Prasinezumab into Phase III Development for Early-Stage Parkinson’s Disease Roche today announced its decision to move forward with Phase III clinical development of prasinezumab — its investigational, humanized monoclonal antibody designed to target and reduce the accumulation of alpha-synuclein — in people living with early-stage Parkinson’s disease.

Disease

Broad Institute

JUNE 16, 2025

Agenda By Rose Circeo June 16, 2025 Breadcrumb Home Agenda Day 1, November 6, 2025 12:00 - 5:00 pm Workshop Day 2, November 7, 2025 8:00 - 6:00 pm Symposium Symposium 8:00 - 9:00 am Registration and Breakfast Opening Session 9:00 - 9:10 am Welcome Sumaiya Iqbal Broad Institute 9:10 - 9:25 am Opening Remarks and Keynote Introduction Stacey Gabriel Broad Institute Keynote 9:30 - 10:30 am Keynote Thomas Miller Iambic Therapeutics Morning Session Chair: Sumaiya Iqbal 10:30 - 11:10 am AI for Patient

Medical Schools

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

The Pharma Data

JUNE 16, 2025

FDA Approves ANDEMBRY (garadacimab-gxii) The First Once-Monthly Prophylactic HAE Therapy Targeting Factor XIIa CSL a leading biotechnology company with a strong track record of developing innovative medicines for patients with rare and serious disorders, today announced that the U.S. Food and Drug Administration (FDA) has approved ANDEMBRY® (garadacimab-gxii) for prophylactic use in the prevention of attacks in patients with hereditary angioedema (HAE) who are 12 years of age or older.

FDA Approval

Crucial Data Solutions

JUNE 16, 2025

Serious adverse events (SAEs) are among the most critical data points collected during a clinical trial. The timeliness and accuracy. The post How EDC-Based SAE Reporting Reduces Time to Detection and Response in Clinical Trials appeared first on Crucial Data Solutions.

Clinical Trials

ProRelix Research

JUNE 16, 2025

The world continues to feel the ripple effects of the COVID-19 pandemic, even into 2025. While vaccines, therapeutics, and preventive measures have significantly reduced the global burden of the disease, […] The post COVID-19 in 2025: Are Decentralized Clinical Trials the New Standard? appeared first on ProRelix Research.

Clinical Trials

Pharma Manufacturing

JUNE 16, 2025

U.S. Pharmacopeia CEO Ronald Piervincenzi told lawmakers that advanced manufacturing technologies will better enable production of pharmaceuticals and pharma ingredients.

Pharmaceuticals

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Collaborative Drug

JUNE 16, 2025

CDD Vault migrates to AWS for enhanced security, global performance, and scalable infrastructure supporting drug discovery research worldwide.

Research

The Pharma Data

JUNE 16, 2025

Lilly to Expand Access to Zepbound: All Approved Doses Now Available in Vials Through LillyDirect’s Self-Pay Pharmacy Solutions Eli Lilly and Company today made a significant announcement aimed at improving patient access to its obesity treatment Zepbound (tirzepatide). The company revealed that the highest approved Zepbound dosages — 12.5 mg and 15 mg — will soon be made available in convenient single-dose vials through LillyDirect’s Self-Pay Pharmacy Solutions.

Pharmacy

Perficient: Drug Development

JUNE 16, 2025

In the world of design, the relationship between Inclusive Design and Universal Design is often misunderstood. While they share the goal of creating usable and accessible experiences , Inclusive Design focuses on offering multiple solutions for diverse needs , while Universal Design refines those solutions into seamless experiences that work for everyone.

Production

Science Daily: Pharmacology News

JUNE 16, 2025

In a leap toward greener tech, researchers at the Paul Scherrer Institute have discovered a way to control magnetic textures using electric fields no bulky magnets needed. Their star material? A strange crystal called copper oxyselenide, where magnetic patterns like helices and cones swirl at low temperatures. By zapping it with different electric fields, they could bend, twist, and even flip these patterns a first in the world of magnetoelectrics.

Research

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Broad Institute

JUNE 16, 2025

#WhyIScienceQ&A: A neuroscientist advocates for stepping outside your comfort zone in research By Allessandra DiCorato June 16, 2025 Breadcrumb Home #WhyIScienceQ&A: A neuroscientist advocates for stepping outside your comfort zone in research Giulia Monti reflects on how studying Alzheimer’s disease alongside researchers focused on kidney disease has helped her grow as a scientist.

Research

Drugs.com

JUNE 16, 2025

MONDAY, June 16, 2025 — Texas has moved to fund research into ibogaine, a psychedelic drug that may help treat addiction, depression, and brain injuries. Gov. Greg Abbott signed a bill last week approving $50 million in state funds for.

Drug Research

Science Daily: Pharmacology News

JUNE 16, 2025

Beetles that can see the color red? That s exactly what scientists discovered in two Mediterranean species that defy the norm of insect vision. While most insects are blind to red, these beetles use specialized photoreceptors to detect it and even show a strong preference for red flowers like poppies and anemones. This breakthrough challenges long-standing assumptions about how flower colors evolved and opens a new path for studying how pollinators influence plant traits over time.

Drugs.com

JUNE 16, 2025

MONDAY, June 16, 2025 — Kidney damage is common during a severe case of COVID-19, but vaccination appears to protect people against this life-threatening side effect, a new study says. Unvaccinated COVID patients with kidney damage severe enough to.

Vaccine

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Science Daily: Pharmacology News

JUNE 16, 2025

A lifelong fascination with nature and fieldwork led this researcher to the world of ethnobiology a field where ecology, culture, and community come together. Investigating how local people relate to species like the anaconda, their work blends traditional knowledge with scientific methods for better conservation. The tale of the mythic Great Snake morphs into economic concerns over vanishing chickens, revealing how cultural beliefs and practical needs coexist.

Research

Drugs.com

JUNE 16, 2025

MONDAY, June 16, 2025 — A new breakthrough can help people with schizophrenia keep up with their psychiatric meds, researchers said.A pill taken just once a week, gradually releasing medicine from within the stomach, can greatly simplify the drug s.

Research

Science Daily: Pharmacology News

JUNE 16, 2025

When faced with a tricky maze task involving hidden information, humans instinctively toggle between two clever mental strategies: simplifying in steps or mentally rewinding. MIT researchers showed that people shift methods based on how reliable their memory is echoed by AI models mimicking the same constraints.

Research

Drugs.com

JUNE 16, 2025

MONDAY, June 16, 2025 — People with ADHD might be prescribed their meds remotely without increasing their risk of addiction, a new study says.Experts have worried that prescribing stimulants like Adderall through telehealth visits might increase s.

Drug Channels

JUNE 16, 2025

This week, I’m rerunning some popular posts while I prepare for Friday’s live video webinar: What’s Next for Retail Pharmacy: Data, Debate, and Disruption. I’ll be joined by special guest Antonio Ciaccia, CEO of 46brooklyn Research, and President of 3 Axis Advisors. Click here to see the original post from March 2025. Next week, Drug Channels Institute (DCI) will release our 2025 Economic Report on U.S.

Specialty Pharmacies

Drugs.com

JUNE 16, 2025

MONDAY, June 16, 2025 — A new breakthrough can help people with schizophrenia keep up with their psychiatric meds, researchers said. A pill taken just once a week, gradually releasing medicine from within the stomach, can greatly simplify the.

Research

Science Daily: Pharmacology News

JUNE 16, 2025

When we focus, switch tasks, or face tough mental challenges, the brain starts to sync its internal rhythms, especially in the midfrontal region. A new study has found that smarter individuals show more precise and flexible coordination of slow theta waves during key decision-making moments. Using EEG recordings and cognitive testing, researchers discovered that it s not constant brainwave synchronization that matters most, but the brain s ability to dynamically adapt its rhythms like a well-tun

Engineering

Drugs.com

JUNE 16, 2025

MONDAY, June 16, 2025 — The turning point in America’s drug overdose (OD) crisis came in August 2023, a new study says.That’s the month when the national drug OD death rate began to decline, researchers reported June 12 in JAMA Network Open.OD death.

Research

Science Daily: Pharmacology News

JUNE 16, 2025

Scientists have built detailed Milky Way simulations under strange new physical laws to probe dark matter, revealing how different versions of the universe might behave and helping us get closer to the real one.

Drugs.com

JUNE 16, 2025

MONDAY, June 16, 2025 — Rheumatoid arthritis (RA) has steadily increased around the world during the past three decades, a new AI-powered study reports.The autoimmune disease affected 17.9 million people worldwide in 2021, a 13% increase from 1990.

Disease