Drug Target Review

JUNE 6, 2025

As antibody-drug conjugates (ADCs) gain traction across oncology and begin to expand into other therapeutic areas, a persistent challenge remains: the design and optimisation of payloads. Across Sygnature Discovery , multidisciplinary teams in Canada and the UK are actively working to address these challenges. With an extensive background in small molecule chemistry, bioconjugation and protein science, these expert teams are leading efforts to place payload development at the centre of ADC innov

Small Molecule

Drugs.com

JUNE 6, 2025

FRIDAY, June 6, 2025 — A new injection to prevent HIV is expected to be approved by the U.S. Food and Drug Administration (FDA) later this month. If approved, the shot — lenacapavir — would be given twice a year and could be a big.

FDA

Alta Sciences

JUNE 6, 2025

Case Study: Two Examples of Successful Automation Integration at Altasciences for Pharmacokinetic Studies pmjackson Fri, 06/06/2025 - 09:01 By Martin Rougée, Optimization Scientist, Bioanalytical Operations Automation offers several advantages to any industry. For a contract research organization (CRO), it can play an integral role in increasing the quality and speed of drug development while reducing costs, repetitive manual tasks, and human error.

Pharmacokinetics

Metabolite Tales Blog

JUNE 6, 2025

Biocatalytic paths to the synthesis of selected metabolites of Iptacopan In a recent paper published in celebration of the 20th birthday of the Swiss Industrial Biocatalysis Consortium, various applications of industrial biocatalysis were described [1]. One example from Novartis highlighted the production of analytical reference standards to access metabolites of Iptacopan (Fabhalta®) to support human ADME studies.

Treatment

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

Clinical Trials

Drug Target Review

JUNE 6, 2025

In recent years, the field of nuclear medicine has undergone a quiet revolution, particularly in its application to oncology. At the forefront of this transformation is Dr Ebrahim Delpassand, a nuclear medicine physician and the driving force behind RadioMedix (RMX), a radiopharmaceutical company focused on developing targeted diagnostics and therapies.

Therapies

The Pharma Data

JUNE 6, 2025

Vertex Showcases Robust Clinical Data Supporting ALYFTREK® and the Critical Role of Sweat Chloride Reduction at 2025 European Cystic Fibrosis Conference New findings reinforce the value of CFTR modulation and the potential of ALYFTREK to enhance health outcomes and quality of life in cystic fibrosis patients Vertex Pharmaceuticals Incorporated, a global biotechnology leader in cystic fibrosis (CF) research and treatment innovation, presented a comprehensive body of new data at the 48th European

Therapies

The Pharma Data

JUNE 6, 2025

Otsuka Unveils Promising Phase 3 Results for Sibeprenlimab in IgA Nephropathy, Marking Significant Proteinuria Reduction and Advancing a Novel APRIL-Targeted Therapy Otsuka Pharmaceutical Development & Commercialization, Inc., in collaboration with Otsuka Pharmaceutical Co., Ltd., has announced encouraging interim findings from the pivotal Phase 3 VISIONARY trial evaluating sibeprenlimab in adults with Immunoglobulin A nephropathy (IgAN), a rare and progressive autoimmune kidney disorder.

Trials

BioPharma Drive: Drug Pricing

JUNE 6, 2025

Gene therapy experts and advocates warning of the sector’s many challenges found a receptive audience in FDA leadership at a regulatory forum Thursday.

Therapies

The Pharma Data

JUNE 6, 2025

Sanofi Highlights Robust Pipeline of Innovations in Rare Blood Disorders at ISTH 2025 Sanofi is poised to take center stage at the 33rd Congress of the International Society on Thrombosis and Haemostasis (ISTH), set to be held in Washington, D.C., from June 21 to 25, 2025. At this premier global meeting focused on thrombosis, hemostasis, and bleeding disorders, Sanofi will present compelling data across 18 scientific abstracts, including five oral presentations.

Disease

Pharma Manufacturing

JUNE 6, 2025

The company is expanding the site’s sterile fill-finish capabilities while sunsetting traditional batch, solid dose production and adopting continuous manufacturing.

Production

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

The Pharma Data

JUNE 6, 2025

AstraZeneca’s Fixed-Duration Calquence Regimen Gains EU Approval for First-Line Treatment of Chronic Lymphocytic Leukaemia AstraZeneca has received European Union (EU) approval for a fixed-duration combination therapy using its Bruton’s tyrosine kinase (BTK) inhibitor Calquence (acalabrutinib) for the treatment of adult patients with previously untreated chronic lymphocytic leukaemia (CLL).

Treatment

BioPharma Drive: Drug Pricing

JUNE 6, 2025

Late-stage results Otsuka presented in IgA nephropathy triggered a sell-off in Vera shares. Elsewhere, investors scrutinized Regenxbio’s Duchenne data and a brain drug study failed.

Drugs

The Pharma Data

JUNE 6, 2025

JCR Pharmaceuticals Celebrates 50 Years of Innovation with Global Website Launch That Reflects Its Expanding Reach and Human-Centric Mission As JCR Pharmaceuticals commemorates its 50th anniversary, the global specialty biopharmaceutical company is marking this major milestone with the launch of a newly designed global website. More than just a digital upgrade, the website represents the company’s transformation from a pioneering Japanese biotech startup into a global force in the field of

Pharmaceuticals

Drugs.com

JUNE 6, 2025

FRIDAY, June 6, 2025 — Immunotherapy combined with chemo can give people a fighting chance against stomach and esophageal cancers, a new clinical trial says.People treated with durvalumab and chemotherapy were much more likely to go into remission.

Clinical Trials

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

thought leadership

JUNE 6, 2025

The journey from compound discovery to market-ready pharmaceutical product is long, complex, and resource-intensive. Only about 1 in 5,000 drug candidates make it to patients 1 , underscoring the need for robust strategies at every stage of development. Medical Information (MI) services are instrumental Product Lifecycle Management (PLM) —ensuring safety, efficacy, and compliance while driving value and maintaining a patient-centric focus.

Compliance

Science Daily: Pharmacology News

JUNE 6, 2025

Scientists have discovered that a molecule known for defending animal immune systems called itaconate also plays a powerful role in plants. Researchers showed that itaconate not only exists in plant cells but actively stimulates growth, such as making corn seedlings grow taller. This surprising crossover between plant and animal biology may unlock new, natural ways to boost agriculture and even improve human health.

Research

The Pharma Data

JUNE 6, 2025

Global Pharmaceutical Contract Sales Outsourcing Market to Reach $24.8 Billion by 2030: Strategic Insights, Regional Trends, and Technological Shifts Reshaping the Landscape The global pharmaceutical contract sales outsourcing (CSO) market is entering a transformative phase, with its value expected to grow from $17.3 billion in 2024 to $24.8 billion by 2030 , reflecting a compound annual growth rate (CAGR) of 6.2%.

Pharmaceutical Companies

Drugs.com

JUNE 6, 2025

FRIDAY, June 6, 2025 — A repurposed diabetes drug can be an effective tool against fatty liver disease, a new clinical trial has found.Dapagliflozin helped people reduce fat levels in their liver and avoid liver scarring that comes with the c.

Disease

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

The Pharma Data

JUNE 6, 2025

WHO Advances Global Chemical Hazard Preparedness with New Comprehensive Online Training Series In a recent address to the Seventy-eighth World Health Assembly , Dr. Tedros Adhanom Ghebreyesus, Director-General of the World Health Organization (WHO), brought critical attention to an often-overlooked public health threat: environmental factors, particularly chemicals, waste, and pollution.

Hospitals

Drugs.com

JUNE 6, 2025

FRIDAY, June 6, 2025 -- The U.S. Food and Drug Administration has granted de novo authorization to CLAIRITY BREAST, a first-in-class, image-based platform that can help predict a woman's risk for breast cancer. CLAIRITY BREAST is designed as a.

FDA

Science Daily: Pharmacology News

JUNE 6, 2025

Scientists have uncovered over 200 new giant viruses lurking in ocean waters that not only help shape marine ecosystems but also manipulate photosynthesis in algae. These massive viruses once nearly invisible to science are now being exposed using powerful supercomputing and a new tool called BEREN. By studying these viruses, researchers hope to predict harmful algal blooms and even explore biotech applications from the novel enzymes found in these viral genomes.

Virus

Drugs.com

JUNE 6, 2025

FRIDAY, June 6, 2025 — There’s a better option than daily aspirin to protect heart patients with a stent against dangerous blood clots, a new study found.A class of drugs called P2Y12 inhibitors that includes ticagrelor and clopidogrel could be mor.

Research

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Science Daily: Pharmacology News

JUNE 6, 2025

An international team of scientists has unveiled the largest and most detailed map of the universe ever created using the James Webb Space Telescope, revealing nearly 800,000 galaxies stretching back to almost the beginning of time. The COSMOS-Web project not only challenges long-held beliefs about galaxy formation in the early universe but also unexpectedly revealed 10 times more galaxies than anticipated along with supermassive black holes Hubble couldn t see.

International

Drugs.com

JUNE 6, 2025

FRIDAY, June 6, 2025 — Attorneys general from four states are asking the U.S. Food and Drug Administration (FDA) to lift restrictions on mifepristone, a pill used in medication abortions. The request came Thursday from top officials in.

FDA

Perficient: Drug Development

JUNE 6, 2025

How Salesforce Turns from Catalyst to Constraint At a time when agility and efficiency are the new currency of business, your Salesforce org should be your most powerful asset—not a tangled web of technical debt, short-term workarounds, and outdated architecture. Yet many companies are feeling the strain. Customizations are built in silos New functionality gets bolted on without long-term planning Reporting becomes a nightmare Instead of accelerating business, Salesforce becomes something te

Packaging

Drugs.com

JUNE 6, 2025

FRIDAY, June 6, 2025 — Freshwater game fish like bluegill, largemouth bass and black crappie in the U.S. commonly carry parasitic flatworms that can infect humans, a new study warns.More than 90% of popular game fish tested in Southern California c.

RAND: Drug Policy and Trends

JUNE 6, 2025

The decline in human intelligence capabilities likely necessitates a shift in intelligence collection sources. Probabilistic crowdsourced forecasting could offer a way to mitigate collection gaps and complement traditional methods by combining human expertise and judgments with data-driven insights.

Drugs.com

JUNE 6, 2025

FRIDAY, June 6, 2025 — Teenagers who are night owls appear to be more self-destructively impulsive, a new study says.Teens who prefer to sleep and wake later are more impulsive than “early bird” teenagers, researchers are scheduled to report at the.

Research

RAND: Drug Policy and Trends

JUNE 6, 2025

Quantum computers pose significant risks to encrypted information, including national security data. The United States plans to pursue post-quantum cryptography, but allied nations should clarify their strategies to ensure secure communication interoperability against quantum threats.

Perficient: Drug Development

JUNE 6, 2025

Artificial Intelligence (AI) is rapidly transforming the landscape of User Experience (UX) in digital design. From automating interface elements to delivering personalized content, AI has become a reliable tool for improving the efficiency, adaptability, and relevance of digital experiences. Despite these advancements, the role of human designers remains vital—especially where creativity, empathy, and ethical decision-making are concerned.

Production

RAND: Drug Policy and Trends

JUNE 6, 2025

Housing is increasingly being viewed as an important contributor to health outcomes. As a result, more health care systems and managed health care plans are getting into the housing business. Will this pay off for their bottom lines?

Perficient: Drug Development

JUNE 6, 2025

In this post, we’ll dive into orchestrating data pipelines with the Databricks Jobs API, empowering you to automate, monitor, and scale workflows seamlessly within the Databricks platform. Why Orchestrate with Databricks Jobs API? When data pipelines become complex involving multiple steps—like running notebooks, updating Delta tables, or training machine learning models—you need a reliable way to automate and manage them with ease.

Engineering