Thu.Mar 06, 2025

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Paralyzed man moves robotic arm with his thoughts

Science Daily: Pharmacology News

Researchers have enabled a man who is paralyzed to control a robotic arm through a device that relays signals from his brain to a computer. He was able to grasp, move and drop objects just by imagining himself performing the actions.

Research 343
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GLP-1 Drugs Improve Outlook For Kidney Transplants

Drugs.com

THURSDAY, March 6, 2025 -- GLP-1 drugs like Ozempic can help kidney transplant patients avoid organ failure and live longer, a new study suggests.The drugs help manage patients type 2 diabetes and promote weight loss, both of which improve the c.

Drugs 297
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Study raises the possibility of a country without butterflies

Science Daily: Pharmacology News

A sweeping study for the first time tallies butterfly data from more than 76,000 surveys across the continental United States. The results: Butterflies -- all of them -- are disappearing.

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Florida Seeks Patient Prescription Data

Drugs.com

THURSDAY, March 6, 2025 -- Florida’s insurance regulator is demanding detailed prescription data on millions of patients, raising alarms over patient privacy. In January, the Florida Office of Insurance Regulation asked pharmacy benefit.

Pharmacy 288
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Memory is impaired in aged rats after 3 days of high-fat eating

Science Daily: Pharmacology News

Just a few days of eating a diet high in saturated fat could be enough to cause memory problems and related brain inflammation in older adults, a new study in rats suggests.

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More Trending

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Possible foundations of human intelligence observed for the first time

Science Daily: Pharmacology News

A study has demonstrated how neurons in the human brain generate memories and establish narratives. Contrary to previous beliefs, individual neurons represent the concepts we learn, regardless of the context in which we encounter them. This allows humans, unlike other animals, to establish higher and more abstract relationships, which lays the foundation of human intelligence.

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Identification of Potent Leucine‐Rich Repeat Kinase 2 Inhibitors by Virtual Screening and Biological Evaluation

Chemical Biology and Drug Design

We reported a virtual screening workflow combining docking and MD simulations to achieve eight compounds for further enzymatic assay and ADMET profile prediction. The results indicated a candidate 2 with IC 50 values of 2.396 and 5.996M against LRRK2 and LRRK2 G2019S, respectively, implying the reliability of this approach. ABSTRACT Parkinson's disease (PD) is the second most common neurodegenerative disease but has limited medications.

Treatment 100
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World's oldest impact crater found, rewriting Earth's ancient history

Science Daily: Pharmacology News

Researchers have discovered the world's oldest known meteorite impact crater, which could significantly redefine our understanding of the origins of life and how our planet was shaped. The team found evidence of a major meteorite impact 3.5 billion years ago.

Research 302
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Fused and Substituted Piperazines as Anticancer Agents: A Review

Chemical Biology and Drug Design

Synthesis, structureactivity relationship, targets, and anticancer activity of fused and substituted piperazines. ABSTRACT Cancer is an abnormal and uncontrolled proliferation of normal cells. The availability of safer anticancer drugs with exceptional selectivity for healthy cells and great efficacy against various cancer forms continues to be a significant obstacle.

DNA 100
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Touchless tech: Control fabrics with a wave of your finger

Science Daily: Pharmacology News

Researchers have created washable and durable magnetic field sensing electronic textiles -- thought to be the first of their kind -- which they say paves the way to transform use in clothing. This technology will allow users to interact with everyday textiles or specialized clothing by simply pointing their finger above a sensor.

Research 287
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Difficult Menopause Could Be Warning Sign For Future Dementia

Drugs.com

THURSDAY, March 6, 2025 -- Hot flashes, night sweats and other symptoms of a difficult menopause could be early warning flags for dementia, a new study suggests.Women who exhibit more menopause symptoms are more likely to develop early signs of.

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Scientists identify genes that make humans and Labradors more likely to become obese

Science Daily: Pharmacology News

Researchers have discovered genes linked to obesity in both Labradors and humans. They say the effects can be over-ridden with a strict diet and exercise regime.

Research 282
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Vertex’s new pain drug gets first coverage nod from major insurer

BioPharma Drive: Drug Pricing

Optum, the pharmacy benefit manager owned by UnitedHealth Group, placed Journavx on some of its commercial formularies in an interim decision while a formal review continues.

Pharmacy 223
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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How footballers' fingers and height can predict their exercise performance

Science Daily: Pharmacology News

New research is studying female professional footballers to find out if if it is possible to predict just how much lactate a person will produce during exercise based on the physical attributes of finger length and height.

Research 281
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Brain Changes May Help Explain Postpartum Depression

Drugs.com

THURSDAY, March 6, 2025 -- Subtle changes in the brain during pregnancy may help explain why some women develop postpartum depression. A study published March 5 in Science Advances found that women with signs of depression after childbirth had.

Science 208
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Plants struggled for millions of years after the world's worst climate catastrophe

Science Daily: Pharmacology News

Scientists have uncovered how plants responded to catastrophic climate changes 250 million years ago. Their findings reveal the long, drawn-out process of ecosystem recovery following one of the most extreme periods of warming in Earth's history: the 'End-Permian Event'.

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Tattoos Might Increase Risk of Lymphoma, Skin Cancer

Drugs.com

THURSDAY, March 6, 2025 -- People put a lot of thought into getting a tattoo the design they desire, the location they prefer and the message their body art will send to others.Most dont think about the impact their tattoo might have on their lon.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Adaptability of some coral reef fish to rising temperatures

Science Daily: Pharmacology News

Researchers have found that reef fish from the Arabian Gulf, the world's hottest sea, exhibit a higher tolerance to temperature fluctuations compared to those from more thermally stable coral reefs. However, the Arabian Gulf hosts fewer fish species overall, indicating that only certain fishes can withstand rising global temperatures.

Research 220
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Tris to ask for approval of dual-acting pain drug

BioPharma Drive: Drug Pricing

Positive data from a pair of acute pain studies convinced the company that its drug, which works differently than existing medications, has a good shot at reaching market.

Drugs 154
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Tropical forests in the Americas are struggling to keep pace with climate change

Science Daily: Pharmacology News

Tropical rainforests play a vital role in global climate regulation and biodiversity conservation. However, a major new study reveals that forests across the Americas are not adapting quickly enough to keep pace with climate change, raising concerns about their long-term resilience.

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Chronic Stress Boosts Stroke Risk In Young Women

Drugs.com

THURSDAY, March 6, 2025 -- Chronic stress can increase young womens risk of stroke, a new study says.Moderate stress increases risk of stroke by 78% in women but not in men, researchers reported in the journal Neurology.More research is needed to.

Research 147
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Tracking polar bears during their most secretive stage of life

Science Daily: Pharmacology News

Researchers have combined satellite collar data with specialized cameras to shed light on one of the most mysterious and important stages in polar bears' lives -- maternal denning, when bears give birth then emerge with their cubs.

Research 171
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Amgen readies pivotal MariTide trials; Novo offers discounted Wegovy

BioPharma Drive: Drug Pricing

Phase 3 studies for Amgen’s closely watched obesity drug were posted on a federal database. Elsewhere, Novo started up an online pharmacy and the FDA cleared testing of a base editing therapy for Duchenne.

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Cancer Screening Rates Rebound Post-Pandemic

Drugs.com

THURSDAY, March 6, 2025 -- Preventive screenings for cancer declined during the pandemic, with lockdowns, social distancing and COVID-19 surges keeping many from needed mammograms and colonoscopies.But breast and colon cancer screening numbers have.

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Synthesis and Antitumor Evaluation of a Novel Class of Chalcone Mannich Base Derivatives

Chemical Biology and Drug Design

A series of novel chalcone Mannich base derivatives were successfully synthesized. Among them, most of the target compounds exhibited strong activities against five different tumor cells. Furthermore, compound I 4 , which has the most potential activity, could induce apoptosis in A549 and A549/DDP cells. ABSTRACT A novel class of chalcone Mannich base derivatives I 1-9 and II 1-11 was synthesized, which exhibited significant antiproliferation activities in five different cancer cells.

Drugs 100
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Breastfeeding Improves Heart Health In Children

Drugs.com

THURSDAY, March 6, 2025 -- Breastfeeding can promote lower blood pressure among children, a new study says.Longer-term breastfeeding appears to populate a babys gut with diverse bacteria that could help lower blood pressure, researchers f.

Research 130
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Advancing and Safeguarding Clinical Research for a Better Tomorrow

Advarra

Institutional review boards (IRBs) play a crucial role in the ever-evolving field of clinical research. For more than 35 years, Advarra has been committed to protecting the rights and welfare of clinical trial participants while helping to improve healthcare outcomes, advancing medical knowledge, and bringing innovative, life-extending treatments to market that benefit millions of patients worldwide.

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Curious About Clinical Studies? Here’s What You Can Expect as a Participant

Antidote

If youve ever wondered what a clinical study is, or what it would be like to participate in one, youre not alone. You probably have a lot of questions about what the process involves and what to expect.

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Finding Patients, Closing Treatment Gaps, and Building Better Messaging through AI and Real-World Data

Fierce BioTech

Finding Patients, Closing Treatment Gaps, and Building Better Messaging through AI and Real-World Data pesurya Thu, 03/06/2025 - 15:09 Tue, 04/08/2025 - 13:00 Resource Type Webinar Joseph Zabinski, PhD, MEM Kathryn Starzyk, ScM Promotion Start Fri, 03/07/2025 - 09:45 Promotion End Sun, 09/07/2025 - 09:45 Traditional commercial strategies focus on known patient populations but what about patients who arent on the radar?