Drugs.com
JANUARY 22, 2025
WEDNESDAY, Jan. 22, 2025 -- Medicare will soon negotiate prices for 15 more drugs as part of an effort to reduce costs for seniors and people with disabilities, federal health officials announced in a news release. The negotiations, made possible.
Science Daily: Pharmacology News
JANUARY 22, 2025
Researchers have developed a way of bioprinting tissues that change shape as a result of cell-generated forces, in the same way that it happens in biological tissues during organ development. The breakthrough science focused on replicating heart tissues, bringing research closer to generating functional, bioprinted organs, which would have broad applications in disease modelling, drug screening and regenerative medicine.
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Chemical Biology and Drug Design
JANUARY 20, 2025
Peptidedrug conjugates (PDCs) were produced by combining a cancer selective cell-penetrating peptide (PDIP) with camptothecin (CPT). The PDCs crossed membranes and cleavable PDCs killed melanoma cells with nanomolar potency. ABSTRACT Drug targeting strategies, such as peptidedrug conjugates (PDCs), have arisen to combat the issue of off-target toxicity that is commonly associated with chemotherapeutic small molecule drugs.
BioPharma Drive: Drug Pricing
JANUARY 23, 2025
In an interview, the CEO discussed trying to gain support from investors hyper-focused on M&A, and competing with Pfizer and Alnylam in a closely watched commercial battle.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Drugs.com
JANUARY 24, 2025
FRIDAY, Jan. 24, 2025 -- People can reverse their type 2 diabetes through a combination of calorie cutting and medication, a small clinical trial says.Overweight and obese adults caused their diabetes to go into remission by following a.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Chemical Biology and Drug Design
JANUARY 22, 2025
The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates. The rising incidence of these infections, coupled with increasing antifungal resistance, underscores the urgent need for novel therapeutic strategies.
BioPharma Drive: Drug Pricing
JANUARY 24, 2025
Brenner, who has worked in the FDA’s Center for Devices and Radiological Health, will lead the agency until a permanent commissioner is confirmed.
Drugs.com
JANUARY 22, 2025
WEDNESDAY, Jan. 22, 2025 -- The U.S. Food and Drug Administration has approved Spravato (esketamine) CIII nasal spray for adults living with major depressive disorder who have had an inadequate response to at least two oral antidepressants.
Science Daily: Pharmacology News
JANUARY 21, 2025
Antibiotics, antivirals, vaccinations and anti-inflammatory medication are associated with reduced risk of dementia, according to new research that looked at health data from over 130 million individuals.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Chemical Biology and Drug Design
JANUARY 20, 2025
A depression database was first constructed, and simvastatin was used as an input to predict potential targets using machine/deep learning methods. Interestingly, the P2X7/NLRP3 pathway was predicted as a potential target for simvastatin. Subsequent Animal experiment's results confirmed this predict. ABSTRACT Depression is a mental health disorder and is the fourth most prevalent disease.
BioPharma Drive: Drug Pricing
JANUARY 22, 2025
The pharma expects a modest financial headwind this year from changes to Medicare prescription drug benefits under the Inflation Reduction Act.
Drugs.com
JANUARY 21, 2025
TUESDAY, Jan. 21, 2025 -- Medicare Advantage isn’t that great an advantage for seniors compared with traditional Medicare, researchers say. The privatized form of Medicare offers more supplemental benefits than traditional Medicare, including.
Science Daily: Pharmacology News
JANUARY 24, 2025
We're nearly one month into 2025, but if you're struggling to hold onto your New Year's resolution, stay strong, as new research shows that forming a healthy habit can take longer than you expect. Researchers found that new habits can begin forming within about two months (median of 59-66 days) but can take up to 335 days to establish.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Chemical Biology and Drug Design
JANUARY 21, 2025
Among prepared 2-phenyl- N -(pyridin-2-yl)acetamides, we identified compounds with promising invitro antimycobacterial activity (notably compound 12 ). In comparison with the previous series, the methylene-extended linker improved antimycobacterial activity. Compound 26 was identified as a promising antiproliferative hit. ABSTRACT Infectious diseases, including bacterial, fungal, and viral, have once again gained urgency in the drug development pipeline after the recent COVID-19 pandemic.
BioPharma Drive: Drug Pricing
JANUARY 22, 2025
CEO Joaquin Duato said the company is positioned for sustained growth in coming years even as competition batters Stelara, one of its top-sellers.
Drugs.com
JANUARY 20, 2025
MONDAY, Jan. 20, 2025 -- Many more Americans are turning to ketamine for kicks, a new study reports.Recreational use of the anesthetic drug among U.S. adults increased 40% between 2021 and 2022, researchers say.That follows a nearly 82% increase in.
Science Daily: Pharmacology News
JANUARY 21, 2025
Astronomers have discovered extremely powerful winds pummeling the equator of WASP-127b, a giant exoplanet. Reaching speeds up to 33,000 km/h, the winds make up the fastest jet-stream of its kind ever measured on a planet. The discovery provides unique insights into the weather patterns of a distant world.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drug Patent Watch
JANUARY 21, 2025
Breaking Down Barriers to Affordable Healthcare: The Power of Biosimilars As we navigate the complex landscape of modern healthcare, one thing is clear: the cost of prescription medications is a significant burden for many patients. The rising cost of brand-name medications has left millions of people struggling to afford the treatments they need to manage their conditions.
Conversations in Drug Development Trends
JANUARY 21, 2025
Jayaprakash Kotha, MBBS, PhD, ASCP (SH), Vice President, Bioanalytical Laboratory Satish Kumar, MBB, Head of Process Improvement Continuous Innovation is a Cornerstone of Bioanalysis Approximately 80% of drugs that begin the research process fail to reach approval. What is one contributing factor that sets the 20% that do apart from the rest? Rigorous procedures to ensure that drugs are effective and safe.
Drugs.com
JANUARY 24, 2025
FRIDAY, Jan. 24, 2025 -- The last duck farm on New York's Long Island is facing an uncertain future after a bird flu outbreak forced the culling of nearly 100,000 ducks. The highly contagious H5N1 avian flu, otherwise known as bird flu, was.
Science Daily: Pharmacology News
JANUARY 23, 2025
Researchers have found that a newly developed diet inspired by the eating habits of non-industrialized societies can significantly reduce the risk of a number of chronic diseases -- and are to share recipes with the public.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
BioPharma Drive: Drug Pricing
JANUARY 24, 2025
An experimental drug called amycretin showed signs it could be more potent than Eli Lilly’s rival Zepbound, though analysts cautioned certain aspects of the study may have inflated its performance.
Drug Patent Watch
JANUARY 21, 2025
Mastering the Art of Drug Patent Portfolio Management As a pharmaceutical professional, you know how crucial it is to navigate the complex landscape of drug patents. With billions of dollars on the line, effective patent portfolio management can make all the difference between success and failure. But what does it take to excel in this field? In our latest blog post, we dive into the best practices for drug patent portfolio management.
Drugs.com
JANUARY 21, 2025
TUESDAY, Jan. 21, 2025 -- Popular GLP-1 medications for weight loss and diabetes may have unexpected benefits for reducing risks for conditions such as substance abuse, psychosis, infections and even dementia. But these drugs also come with risks.
Science Daily: Pharmacology News
JANUARY 20, 2025
A new study has described a phenomenon researchers refer to as 'contagious urinations.' The study in 20 captive chimpanzees living at the Kumamoto Sanctuary in Japan shows that, when one chimp pees, others are more likely to follow.
BioPharma Drive: Drug Pricing
JANUARY 23, 2025
The China-based cancer drug developer’s offering will fund testing of medicines for several blood malignancies — one of which is part of an alliance with Takeda.
addgene Blog
JANUARY 21, 2025
One of the most pivotal decisions many PhDs face when transitioning from academia to industry is whether to stay hands-on in the lab or pivot to a managerial role. For those contemplating the leap into management, the journey can be as exciting as it is challenging.
Drugs.com
JANUARY 21, 2025
TUESDAY, Jan. 21, 2025 (HealthDay New) -- A landmark U.S. Supreme Court decision barring job discrimination significantly eased the minds of LGBTQ+ workers, a new study says.The court extended employment protections to nearly 3.6 million LGBTQ+.
Science Daily: Pharmacology News
JANUARY 23, 2025
The fossilized neck bone of a flying reptile unearthed in Canada shows tell-tale signs of being bitten by a crocodile-like creature 76 million years ago, according to a new study.
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